PGLYRP4 (peptidoglycan recognition protein 4)

2014-11-01  

Identity

HGNC
PGLYRP4
LOCATION
1q21.3
LOCUSID
57115
ALIAS
PGLYRPIbeta,PGRP-Ibeta,PGRPIB,SBBI67

Other Information

Locus ID:

NCBI: 57115
MIM: 608198
HGNC: 30015
Ensembl: ENSG00000163218

Variants:

dbSNP: 57115
ClinVar: 57115
TCGA: ENSG00000163218
COSMIC: PGLYRP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163218ENST00000359650Q96LB8
ENSG00000163218ENST00000368739Q96LB8

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Antimicrobial peptidesREACTOMER-HSA-6803157

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164713366Tumor necrosis factor alpha (TNF-alpha) inhibitorsChemicalClinicalAnnotationassociatedPD27670765
PA445451PsoriasisDiseaseClinicalAnnotationassociatedPD27670765

References

Pubmed IDYearTitleCitations
163546522006Peptidoglycan recognition proteins are a new class of human bactericidal proteins.66
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
163628252006Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21.13
248381822014Peptidoglycan recognition protein genes and risk of Parkinson's disease.10
260390762015A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins.7

Citation

Dessen P

PGLYRP4 (peptidoglycan recognition protein 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71866/pglyrp4