Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PGRMC1 (progesterone receptor membrane component 1)

Identity

Alias (NCBI)Dap1
HPR6.6
IZA
MPR
HGNC (Hugo) PGRMC1
HGNC Alias symbHPR6.6
LocusID (NCBI) 10857
Atlas_Id 45676
Location Xq24  [Link to chromosome band Xq24]
Location_base_pair Starts at 119236285 and ends at 119244466 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PGRMC1 (Xq24) / PGRMC1 (Xq24)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)PGRMC1   16090
Cards
Entrez_Gene (NCBI)PGRMC1  10857  progesterone receptor membrane component 1
AliasesDap1; HPR6.6; IZA; MPR
GeneCards (Weizmann)PGRMC1
Ensembl hg19 (Hinxton)ENSG00000101856 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101856 [Gene_View]  ENSG00000101856 [Sequence]  chrX:119236285-119244466 [Contig_View]  PGRMC1 [Vega]
ICGC DataPortalENSG00000101856
TCGA cBioPortalPGRMC1
AceView (NCBI)PGRMC1
Genatlas (Paris)PGRMC1
WikiGenes10857
SOURCE (Princeton)PGRMC1
Genetics Home Reference (NIH)PGRMC1
Genomic and cartography
GoldenPath hg38 (UCSC)PGRMC1  -     chrX:119236285-119244466 +  Xq24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PGRMC1  -     Xq24   [Description]    (hg19-Feb_2009)
GoldenPathPGRMC1 - Xq24 [CytoView hg19]  PGRMC1 - Xq24 [CytoView hg38]
ImmunoBaseENSG00000101856
genome Data Viewer NCBIPGRMC1 [Mapview hg19]  
OMIM300435   
Gene and transcription
Genbank (Entrez)AK293618 AK313956 BC034238 CR456993 CX762728
RefSeq transcript (Entrez)NM_001282621 NM_006667
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PGRMC1
Alternative Splicing GalleryENSG00000101856
Gene ExpressionPGRMC1 [ NCBI-GEO ]   PGRMC1 [ EBI - ARRAY_EXPRESS ]   PGRMC1 [ SEEK ]   PGRMC1 [ MEM ]
Gene Expression Viewer (FireBrowse)PGRMC1 [ Firebrowse - Broad ]
GenevisibleExpression of PGRMC1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10857
GTEX Portal (Tissue expression)PGRMC1
Human Protein AtlasENSG00000101856-PGRMC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00264   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00264  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00264
Splice isoforms : SwissVarO00264
PhosPhoSitePlusO00264
Domains : Interpro (EBI)Cyt_B5-like_heme/steroid-bd    Cyt_B5-like_heme/steroid_sf   
Domain families : Pfam (Sanger)Cyt-b5 (PF00173)   
Domain families : Pfam (NCBI)pfam00173   
Domain families : Smart (EMBL)Cyt-b5 (SM01117)  
Conserved Domain (NCBI)PGRMC1
DMDM Disease mutations10857
Blocks (Seattle)PGRMC1
PDB (RSDB)4X8Y   
PDB Europe4X8Y   
PDB (PDBSum)4X8Y   
PDB (IMB)4X8Y   
Structural Biology KnowledgeBase4X8Y   
SCOP (Structural Classification of Proteins)4X8Y   
CATH (Classification of proteins structures)4X8Y   
SuperfamilyO00264
Human Protein Atlas [tissue]ENSG00000101856-PGRMC1 [tissue]
Peptide AtlasO00264
HPRD02338
IPIIPI00220739   IPI00922847   
Protein Interaction databases
DIP (DOE-UCLA)O00264
IntAct (EBI)O00264
FunCoupENSG00000101856
BioGRIDPGRMC1
STRING (EMBL)PGRMC1
ZODIACPGRMC1
Ontologies - Pathways
QuickGOO00264
Ontology : AmiGOamyloid-beta binding  steroid binding  protein binding  mitochondrial outer membrane  endoplasmic reticulum  plasma membrane  integral component of plasma membrane  heme biosynthetic process  endomembrane system  membrane  membrane  heme binding  smooth endoplasmic reticulum membrane  specific granule membrane  protein homodimerization activity  neuron projection  neuronal cell body  neutrophil degranulation  cell body  synapse  metal ion binding  
Ontology : EGO-EBIamyloid-beta binding  steroid binding  protein binding  mitochondrial outer membrane  endoplasmic reticulum  plasma membrane  integral component of plasma membrane  heme biosynthetic process  endomembrane system  membrane  membrane  heme binding  smooth endoplasmic reticulum membrane  specific granule membrane  protein homodimerization activity  neuron projection  neuronal cell body  neutrophil degranulation  cell body  synapse  metal ion binding  
NDEx NetworkPGRMC1
Atlas of Cancer Signalling NetworkPGRMC1
Wikipedia pathwaysPGRMC1
Orthology - Evolution
OrthoDB10857
GeneTree (enSembl)ENSG00000101856
Phylogenetic Trees/Animal Genes : TreeFamPGRMC1
HOGENOMO00264
Homologs : HomoloGenePGRMC1
Homology/Alignments : Family Browser (UCSC)PGRMC1
Gene fusions - Rearrangements
Fusion : QuiverPGRMC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPGRMC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PGRMC1
dbVarPGRMC1
ClinVarPGRMC1
MonarchPGRMC1
1000_GenomesPGRMC1 
Exome Variant ServerPGRMC1
GNOMAD BrowserENSG00000101856
Varsome BrowserPGRMC1
Genetic variants : HAPMAP10857
Genomic Variants (DGV)PGRMC1 [DGVbeta]
DECIPHERPGRMC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPGRMC1 
Mutations
ICGC Data PortalPGRMC1 
TCGA Data PortalPGRMC1 
Broad Tumor PortalPGRMC1
OASIS PortalPGRMC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPGRMC1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPGRMC1
Mutations and Diseases : HGMDPGRMC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch PGRMC1
DgiDB (Drug Gene Interaction Database)PGRMC1
DoCM (Curated mutations)PGRMC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PGRMC1 (select a term)
intoGenPGRMC1
Cancer3DPGRMC1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300435   
Orphanet
DisGeNETPGRMC1
MedgenPGRMC1
Genetic Testing Registry PGRMC1
NextProtO00264 [Medical]
TSGene10857
GENETestsPGRMC1
Target ValidationPGRMC1
Huge Navigator PGRMC1 [HugePedia]
snp3D : Map Gene to Disease10857
BioCentury BCIQPGRMC1
ClinGenPGRMC1
Clinical trials, drugs, therapy
Protein Interactions : CTD10857
Pharm GKB GenePA33248
Clinical trialPGRMC1
Miscellaneous
canSAR (ICR)PGRMC1 (select the gene name)
HarmonizomePGRMC1
DataMed IndexPGRMC1
Probes
Litterature
PubMed134 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePGRMC1
EVEXPGRMC1
GoPubMedPGRMC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:26:31 CEST 2020

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