Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PGRMC2 (progesterone receptor membrane component 2)

Identity

Alias_symbol (synonym)PMBP
DG6
Other alias
HGNC (Hugo) PGRMC2
LocusID (NCBI) 10424
Atlas_Id 53736
Location 4q28.2  [Link to chromosome band 4q28]
Location_base_pair Starts at 128269237 and ends at 128288829 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PGRMC2 (4q28.2) / IRF2BP2 (1q42.3)PRRX1 (1q24.2) / PGRMC2 (4q28.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PGRMC2   16089
Cards
Entrez_Gene (NCBI)PGRMC2  10424  progesterone receptor membrane component 2
AliasesDG6; PMBP
GeneCards (Weizmann)PGRMC2
Ensembl hg19 (Hinxton)ENSG00000164040 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164040 [Gene_View]  chr4:128269237-128288829 [Contig_View]  PGRMC2 [Vega]
ICGC DataPortalENSG00000164040
TCGA cBioPortalPGRMC2
AceView (NCBI)PGRMC2
Genatlas (Paris)PGRMC2
WikiGenes10424
SOURCE (Princeton)PGRMC2
Genetics Home Reference (NIH)PGRMC2
Genomic and cartography
GoldenPath hg38 (UCSC)PGRMC2  -     chr4:128269237-128288829 -  4q28.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PGRMC2  -     4q28.2   [Description]    (hg19-Feb_2009)
EnsemblPGRMC2 - 4q28.2 [CytoView hg19]  PGRMC2 - 4q28.2 [CytoView hg38]
Mapping of homologs : NCBIPGRMC2 [Mapview hg19]  PGRMC2 [Mapview hg38]
OMIM607735   
Gene and transcription
Genbank (Entrez)AJ002030 AK091741 AK094949 AK131272 BC016692
RefSeq transcript (Entrez)NM_006320
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PGRMC2
Cluster EST : UnigeneHs.507910 [ NCBI ]
CGAP (NCI)Hs.507910
Alternative Splicing GalleryENSG00000164040
Gene ExpressionPGRMC2 [ NCBI-GEO ]   PGRMC2 [ EBI - ARRAY_EXPRESS ]   PGRMC2 [ SEEK ]   PGRMC2 [ MEM ]
Gene Expression Viewer (FireBrowse)PGRMC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10424
GTEX Portal (Tissue expression)PGRMC2
Human Protein AtlasENSG00000164040-PGRMC2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15173   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15173  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15173
Splice isoforms : SwissVarO15173
PhosPhoSitePlusO15173
Domains : Interpro (EBI)Cyt_B5-like_heme/steroid-bd   
Domain families : Pfam (Sanger)Cyt-b5 (PF00173)   
Domain families : Pfam (NCBI)pfam00173   
Domain families : Smart (EMBL)Cyt-b5 (SM01117)  
Conserved Domain (NCBI)PGRMC2
DMDM Disease mutations10424
Blocks (Seattle)PGRMC2
SuperfamilyO15173
Human Protein Atlas [tissue]ENSG00000164040-PGRMC2 [tissue]
Peptide AtlasO15173
HPRD09665
IPIIPI01015100   IPI00477862   IPI00005202   
Protein Interaction databases
DIP (DOE-UCLA)O15173
IntAct (EBI)O15173
FunCoupENSG00000164040
BioGRIDPGRMC2
STRING (EMBL)PGRMC2
ZODIACPGRMC2
Ontologies - Pathways
QuickGOO15173
Ontology : AmiGOsteroid hormone receptor activity  steroid binding  protein binding  nuclear envelope  membrane  membrane  integral component of membrane  heme binding  steroid hormone mediated signaling pathway  
Ontology : EGO-EBIsteroid hormone receptor activity  steroid binding  protein binding  nuclear envelope  membrane  membrane  integral component of membrane  heme binding  steroid hormone mediated signaling pathway  
NDEx NetworkPGRMC2
Atlas of Cancer Signalling NetworkPGRMC2
Wikipedia pathwaysPGRMC2
Orthology - Evolution
OrthoDB10424
GeneTree (enSembl)ENSG00000164040
Phylogenetic Trees/Animal Genes : TreeFamPGRMC2
HOVERGENO15173
HOGENOMO15173
Homologs : HomoloGenePGRMC2
Homology/Alignments : Family Browser (UCSC)PGRMC2
Gene fusions - Rearrangements
Tumor Fusion PortalPGRMC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPGRMC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PGRMC2
dbVarPGRMC2
ClinVarPGRMC2
1000_GenomesPGRMC2 
Exome Variant ServerPGRMC2
ExAC (Exome Aggregation Consortium)ENSG00000164040
GNOMAD BrowserENSG00000164040
Genetic variants : HAPMAP10424
Genomic Variants (DGV)PGRMC2 [DGVbeta]
DECIPHERPGRMC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPGRMC2 
Mutations
ICGC Data PortalPGRMC2 
TCGA Data PortalPGRMC2 
Broad Tumor PortalPGRMC2
OASIS PortalPGRMC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPGRMC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPGRMC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PGRMC2
DgiDB (Drug Gene Interaction Database)PGRMC2
DoCM (Curated mutations)PGRMC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PGRMC2 (select a term)
intoGenPGRMC2
Cancer3DPGRMC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607735   
Orphanet
DisGeNETPGRMC2
MedgenPGRMC2
Genetic Testing Registry PGRMC2
NextProtO15173 [Medical]
TSGene10424
GENETestsPGRMC2
Target ValidationPGRMC2
Huge Navigator PGRMC2 [HugePedia]
snp3D : Map Gene to Disease10424
BioCentury BCIQPGRMC2
ClinGenPGRMC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10424
Chemical/Pharm GKB GenePA33249
Clinical trialPGRMC2
Miscellaneous
canSAR (ICR)PGRMC2 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePGRMC2
EVEXPGRMC2
GoPubMedPGRMC2
iHOPPGRMC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:28:32 CET 2017

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