PHACTR3 (phosphatase and actin regulator 3)

2010-04-01  

Identity

HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
C20orf101,H17739,PPP1R123,SCAPIN1,SCAPININ
FUSION GENES

Other Information

Locus ID:

NCBI: 116154
MIM: 608725
HGNC: 15833
Ensembl: ENSG00000087495

Variants:

dbSNP: 116154
ClinVar: 116154
TCGA: ENSG00000087495
COSMIC: PHACTR3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000087495ENST00000355648Q96KR7
ENSG00000087495ENST00000359926Q96KR7
ENSG00000087495ENST00000361300Q96KR7
ENSG00000087495ENST00000371015Q96KR7
ENSG00000087495ENST00000395636Q96KR7
ENSG00000087495ENST00000434923F6RP66
ENSG00000087495ENST00000541461Q96KR7

Expression (GTEx)

0
10
20
30
40
50
60

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
194737192010Identification of genes associated with non-small-cell lung cancer promotion and progression.40
129255322003Scapinin, a putative protein phosphatase-1 regulatory subunit associated with the nuclear nonchromatin structure.17
191589532009Scapinin, the protein phosphatase 1 binding protein, enhances cell spreading and motility by interacting with the actin cytoskeleton.15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
221350452012DNA methylation of phosphatase and actin regulator 3 detects colorectal cancer in stool and complements FIT.10
214870132011Scapinin-induced inhibition of axon elongation is attenuated by phosphorylation and translocation to the cytoplasm.8
169740802006Genomic organization and expression pattern of scapinin (PHACTR3) in mouse and human.2

Citation

Dessen P

PHACTR3 (phosphatase and actin regulator 3)

Atlas Genet Cytogenet Oncol Haematol. 2010-04-01

Online version: http://atlasgeneticsoncology.org/gene/51442/phactr3