PHF13 (PHD finger protein 13)

2014-11-01  

Identity

HGNC
PHF13
LOCATION
1p36.31
LOCUSID
148479
ALIAS
PHF5,SPOC1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 148479
HGNC: 22983
Ensembl: ENSG00000116273

Variants:

dbSNP: 148479
ClinVar: 148479
TCGA: ENSG00000116273
COSMIC: PHF13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116273ENST00000377648Q86YI8
ENSG00000116273ENST00000377648A0A158RFV6

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
242780212013SPOC1-mediated antiviral host cell response is antagonized early in human adenovirus type 5 infection.28
196384092009SPOC1: a novel PHD-containing protein modulating chromatin structure and mitotic chromosome condensation.13
297433582018Chromatin-Remodeling Factor SPOC1 Acts as a Cellular Restriction Factor against Human Cytomegalovirus by Repressing the Major Immediate Early Promoter.7
272233242016PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3.6
290212152017Dual role of the chromatin-binding factor PHF13 in the pre- and post-integration phases of HIV-1 replication.5

Citation

Dessen P

PHF13 (PHD finger protein 13)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71882/phf13