PHOSPHO1 (phosphoethanolamine/phosphocholine phosphatase 1)

2014-11-01 Affiliation

Identity

HGNC

PHOSPHO1

LOCATION

17q21.32

LOCUSID

162466

ALIAS

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 162466
HGNC: 16815
Ensembl: ENSG00000173868

Variants:

dbSNP: 162466
ClinVar: 162466
TCGA: ENSG00000173868
COSMIC: PHOSPHO1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000173868	ENST00000310544	Q8TCT1
ENSG00000173868	ENST00000413580	Q8TCT1
ENSG00000173868	ENST00000503902	D6RB58
ENSG00000173868	ENST00000511066	D6RHH9
ENSG00000173868	ENST00000512250	D6RIT6
ENSG00000173868	ENST00000514112	Q8TCT1
ENSG00000173868	ENST00000574638	I3L4N1

Expression (GTEx)

100

150

200

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Glycerophospholipid metabolism	KEGG	ko00564
Glycerophospholipid metabolism	KEGG	hsa00564
Metabolic pathways	KEGG	hsa01100
Metabolism	REACTOME	R-HSA-1430728
Metabolism of lipids and lipoproteins	REACTOME	R-HSA-556833
Phospholipid metabolism	REACTOME	R-HSA-1483257
Glycerophospholipid biosynthesis	REACTOME	R-HSA-1483206
Synthesis of PE	REACTOME	R-HSA-1483213
Synthesis of PC	REACTOME	R-HSA-1483191

References

Pubmed ID	Year	Title	Citations
27148772	2016	DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk.	39
28173150	2016	Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study.	21
19453261	2009	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	20
16054448	2005	Probing the substrate specificities of human PHOSPHO1 and PHOSPHO2.	13
24533943	2014	Role of bone-type tissue-nonspecific alkaline phosphatase and PHOSPO1 in vascular calcification.	8
18471996	2008	Identification of a novel splice variant of the haloacid dehalogenase: PHOSPHO1.	1

Citation

Dessen P

PHOSPHO1 (phosphoethanolamine/phosphocholine phosphatase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71891/phospho1