Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PHOSPHO1 (phosphoethanolamine/phosphocholine phosphatase)

Identity

Alias_namesphosphatase, orphan 1
Other alias-
HGNC (Hugo) PHOSPHO1
LocusID (NCBI) 162466
Atlas_Id 71891
Location 17q21.32  [Link to chromosome band 17q21]
Location_base_pair Starts at 49223370 and ends at 49230766 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EIF4A1 (17p13.1) / PHOSPHO1 (17q21.32)MED1 (17q12) / PHOSPHO1 (17q21.32)PHOSPHO1 (17q21.32) / KRT23 (17q21.2)
MED1 PHOSPHO1EIF4A1 PHOSPHO1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PHOSPHO1   16815
Cards
Entrez_Gene (NCBI)PHOSPHO1  162466  phosphoethanolamine/phosphocholine phosphatase
Aliases
GeneCards (Weizmann)PHOSPHO1
Ensembl hg19 (Hinxton)ENSG00000173868 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173868 [Gene_View]  chr17:49223370-49230766 [Contig_View]  PHOSPHO1 [Vega]
ICGC DataPortalENSG00000173868
TCGA cBioPortalPHOSPHO1
AceView (NCBI)PHOSPHO1
Genatlas (Paris)PHOSPHO1
WikiGenes162466
SOURCE (Princeton)PHOSPHO1
Genetics Home Reference (NIH)PHOSPHO1
Genomic and cartography
GoldenPath hg38 (UCSC)PHOSPHO1  -     chr17:49223370-49230766 -  17q21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PHOSPHO1  -     17q21.32   [Description]    (hg19-Feb_2009)
EnsemblPHOSPHO1 - 17q21.32 [CytoView hg19]  PHOSPHO1 - 17q21.32 [CytoView hg38]
Mapping of homologs : NCBIPHOSPHO1 [Mapview hg19]  PHOSPHO1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AJ457189 BC029931 BC117187 BC143884
RefSeq transcript (Entrez)NM_001143804 NM_178500
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PHOSPHO1
Cluster EST : UnigeneHs.405607 [ NCBI ]
CGAP (NCI)Hs.405607
Alternative Splicing GalleryENSG00000173868
Gene ExpressionPHOSPHO1 [ NCBI-GEO ]   PHOSPHO1 [ EBI - ARRAY_EXPRESS ]   PHOSPHO1 [ SEEK ]   PHOSPHO1 [ MEM ]
Gene Expression Viewer (FireBrowse)PHOSPHO1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)162466
GTEX Portal (Tissue expression)PHOSPHO1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TCT1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TCT1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TCT1
Splice isoforms : SwissVarQ8TCT1
PhosPhoSitePlusQ8TCT1
Domains : Interpro (EBI)HAD-like_dom    Pase_PHOSPHO-typ    PyrdxlP_Pase-rel   
Domain families : Pfam (Sanger)Put_Phosphatase (PF06888)   
Domain families : Pfam (NCBI)pfam06888   
Conserved Domain (NCBI)PHOSPHO1
DMDM Disease mutations162466
Blocks (Seattle)PHOSPHO1
SuperfamilyQ8TCT1
Human Protein AtlasENSG00000173868
Peptide AtlasQ8TCT1
HPRD17847
IPIIPI00152434   IPI00916923   IPI00967273   IPI00964719   IPI00964430   
Protein Interaction databases
DIP (DOE-UCLA)Q8TCT1
IntAct (EBI)Q8TCT1
FunCoupENSG00000173868
BioGRIDPHOSPHO1
STRING (EMBL)PHOSPHO1
ZODIACPHOSPHO1
Ontologies - Pathways
QuickGOQ8TCT1
Ontology : AmiGOendochondral ossification  proteinaceous extracellular matrix  cytosol  phosphatidylethanolamine biosynthetic process  phosphatidylcholine biosynthetic process  dephosphorylation  pyrophosphatase activity  phosphatase activity  regulation of bone mineralization  bone mineralization involved in bone maturation  metal ion binding  phosphocholine phosphatase activity  phosphoethanolamine phosphatase activity  extracellular membrane-bounded organelle  
Ontology : EGO-EBIendochondral ossification  proteinaceous extracellular matrix  cytosol  phosphatidylethanolamine biosynthetic process  phosphatidylcholine biosynthetic process  dephosphorylation  pyrophosphatase activity  phosphatase activity  regulation of bone mineralization  bone mineralization involved in bone maturation  metal ion binding  phosphocholine phosphatase activity  phosphoethanolamine phosphatase activity  extracellular membrane-bounded organelle  
Pathways : KEGGGlycerophospholipid metabolism   
NDEx NetworkPHOSPHO1
Atlas of Cancer Signalling NetworkPHOSPHO1
Wikipedia pathwaysPHOSPHO1
Orthology - Evolution
OrthoDB162466
GeneTree (enSembl)ENSG00000173868
Phylogenetic Trees/Animal Genes : TreeFamPHOSPHO1
HOVERGENQ8TCT1
HOGENOMQ8TCT1
Homologs : HomoloGenePHOSPHO1
Homology/Alignments : Family Browser (UCSC)PHOSPHO1
Gene fusions - Rearrangements
Fusion: TCGAMED1 PHOSPHO1
Fusion: TCGAEIF4A1 PHOSPHO1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPHOSPHO1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PHOSPHO1
dbVarPHOSPHO1
ClinVarPHOSPHO1
1000_GenomesPHOSPHO1 
Exome Variant ServerPHOSPHO1
ExAC (Exome Aggregation Consortium)PHOSPHO1 (select the gene name)
Genetic variants : HAPMAP162466
Genomic Variants (DGV)PHOSPHO1 [DGVbeta]
DECIPHERPHOSPHO1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPHOSPHO1 
Mutations
ICGC Data PortalPHOSPHO1 
TCGA Data PortalPHOSPHO1 
Broad Tumor PortalPHOSPHO1
OASIS PortalPHOSPHO1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPHOSPHO1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPHOSPHO1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PHOSPHO1
DgiDB (Drug Gene Interaction Database)PHOSPHO1
DoCM (Curated mutations)PHOSPHO1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PHOSPHO1 (select a term)
intoGenPHOSPHO1
Cancer3DPHOSPHO1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPHOSPHO1
Genetic Testing Registry PHOSPHO1
NextProtQ8TCT1 [Medical]
TSGene162466
GENETestsPHOSPHO1
Target ValidationPHOSPHO1
Huge Navigator PHOSPHO1 [HugePedia]
snp3D : Map Gene to Disease162466
BioCentury BCIQPHOSPHO1
ClinGenPHOSPHO1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD162466
Chemical/Pharm GKB GenePA33276
Clinical trialPHOSPHO1
Miscellaneous
canSAR (ICR)PHOSPHO1 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePHOSPHO1
EVEXPHOSPHO1
GoPubMedPHOSPHO1
iHOPPHOSPHO1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 16:35:51 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.