Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PHRF1 (PHD and ring finger domains 1)

Identity

Alias_namesRNF221
Alias_symbol (synonym)KIAA1542
PPP1R125
Other alias
HGNC (Hugo) PHRF1
LocusID (NCBI) 57661
Atlas_Id 53938
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 576446 and ends at 612222 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PHRF1 (11p15.5) / C3 (19p13.3)PHRF1 (11p15.5) / EPCAM (2p21)PHRF1 (11p15.5) / HCFC1R1 (16p13.3)
PHRF1 (11p15.5) / LRRC56 (11p15.5)TSPAN1 (1p34.1) / PHRF1 (11p15.5)PHRF1 11p15.5 / LRRC56 11p15.5

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PHRF1   24351
Cards
Entrez_Gene (NCBI)PHRF1  57661  PHD and ring finger domains 1
AliasesPPP1R125; RNF221
GeneCards (Weizmann)PHRF1
Ensembl hg19 (Hinxton)ENSG00000070047 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000070047 [Gene_View]  chr11:576446-612222 [Contig_View]  PHRF1 [Vega]
ICGC DataPortalENSG00000070047
TCGA cBioPortalPHRF1
AceView (NCBI)PHRF1
Genatlas (Paris)PHRF1
WikiGenes57661
SOURCE (Princeton)PHRF1
Genetics Home Reference (NIH)PHRF1
Genomic and cartography
GoldenPath hg38 (UCSC)PHRF1  -     chr11:576446-612222 +  11p15.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PHRF1  -     11p15.5   [Description]    (hg19-Feb_2009)
EnsemblPHRF1 - 11p15.5 [CytoView hg19]  PHRF1 - 11p15.5 [CytoView hg38]
Mapping of homologs : NCBIPHRF1 [Mapview hg19]  PHRF1 [Mapview hg38]
OMIM611780   
Gene and transcription
Genbank (Entrez)AB040975 BC004950 BC013381 BC029651 BC041631
RefSeq transcript (Entrez)NM_001286581 NM_001286582 NM_001286583 NM_020901
RefSeq genomic (Entrez)NC_000011 NC_018922 NT_187586
Consensus coding sequences : CCDS (NCBI)PHRF1
Cluster EST : UnigeneHs.325838 [ NCBI ]
CGAP (NCI)Hs.325838
Alternative Splicing GalleryENSG00000070047
Gene ExpressionPHRF1 [ NCBI-GEO ]   PHRF1 [ EBI - ARRAY_EXPRESS ]   PHRF1 [ SEEK ]   PHRF1 [ MEM ]
Gene Expression Viewer (FireBrowse)PHRF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57661
GTEX Portal (Tissue expression)PHRF1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P1Y6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P1Y6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P1Y6
Splice isoforms : SwissVarQ9P1Y6
PhosPhoSitePlusQ9P1Y6
Domaine pattern : Prosite (Expaxy)ZF_PHD_1 (PS01359)    ZF_PHD_2 (PS50016)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_FYVE_PHD    Znf_PHD    Znf_PHD-finger    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)PHD (PF00628)    zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam00628    pfam13639   
Domain families : Smart (EMBL)PHD (SM00249)  RING (SM00184)  
Conserved Domain (NCBI)PHRF1
DMDM Disease mutations57661
Blocks (Seattle)PHRF1
SuperfamilyQ9P1Y6
Human Protein AtlasENSG00000070047
Peptide AtlasQ9P1Y6
HPRD13870
IPIIPI00001813   IPI00827706   IPI00942878   IPI00978364   IPI01013297   
Protein Interaction databases
DIP (DOE-UCLA)Q9P1Y6
IntAct (EBI)Q9P1Y6
FunCoupENSG00000070047
BioGRIDPHRF1
STRING (EMBL)PHRF1
ZODIACPHRF1
Ontologies - Pathways
QuickGOQ9P1Y6
Ontology : AmiGOtranscription from RNA polymerase II promoter  mRNA processing  zinc ion binding  membrane  protein domain specific binding  RNA polymerase binding  
Ontology : EGO-EBItranscription from RNA polymerase II promoter  mRNA processing  zinc ion binding  membrane  protein domain specific binding  RNA polymerase binding  
NDEx NetworkPHRF1
Atlas of Cancer Signalling NetworkPHRF1
Wikipedia pathwaysPHRF1
Orthology - Evolution
OrthoDB57661
GeneTree (enSembl)ENSG00000070047
Phylogenetic Trees/Animal Genes : TreeFamPHRF1
HOVERGENQ9P1Y6
HOGENOMQ9P1Y6
Homologs : HomoloGenePHRF1
Homology/Alignments : Family Browser (UCSC)PHRF1
Gene fusions - Rearrangements
Fusion : MitelmanPHRF1/LRRC56 [11p15.5/11p15.5]  
Fusion : MitelmanTSPAN1/PHRF1 [1p34.1/11p15.5]  [t(1;11)(p34;p15)]  
Fusion: TCGAPHRF1 11p15.5 LRRC56 11p15.5 BRCA LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPHRF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PHRF1
dbVarPHRF1
ClinVarPHRF1
1000_GenomesPHRF1 
Exome Variant ServerPHRF1
ExAC (Exome Aggregation Consortium)PHRF1 (select the gene name)
Genetic variants : HAPMAP57661
Genomic Variants (DGV)PHRF1 [DGVbeta]
DECIPHERPHRF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPHRF1 
Mutations
ICGC Data PortalPHRF1 
TCGA Data PortalPHRF1 
Broad Tumor PortalPHRF1
OASIS PortalPHRF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPHRF1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPHRF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PHRF1
DgiDB (Drug Gene Interaction Database)PHRF1
DoCM (Curated mutations)PHRF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PHRF1 (select a term)
intoGenPHRF1
Cancer3DPHRF1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611780   
Orphanet
MedgenPHRF1
Genetic Testing Registry PHRF1
NextProtQ9P1Y6 [Medical]
TSGene57661
GENETestsPHRF1
Target ValidationPHRF1
Huge Navigator PHRF1 [HugePedia]
snp3D : Map Gene to Disease57661
BioCentury BCIQPHRF1
ClinGenPHRF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57661
Chemical/Pharm GKB GenePA164724459
Clinical trialPHRF1
Miscellaneous
canSAR (ICR)PHRF1 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePHRF1
EVEXPHRF1
GoPubMedPHRF1
iHOPPHRF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:03:15 CEST 2017

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