Atlas of Genetics and Cytogenetics in Oncology and Haematology

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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

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PI16 (peptidase inhibitor 16)


Other namesCRISP9
HGNC (Hugo) PI16
LocusID (NCBI) 221476
Location 6p21.2
Location_base_pair Starts at 36916039 and ends at 36932613 bp from pter ( according to hg19-Feb_2009)

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

HGNC (Hugo)PI16   21245
Entrez_Gene (NCBI)PI16  221476  peptidase inhibitor 16
GeneCards (Weizmann)PI16
Ensembl hg19 (Hinxton)ENSG00000164530 [Gene_View]  chr6:36916039-36932613 [Contig_View]  PI16 [Vega]
Ensembl hg38 (Hinxton)ENSG00000164530 [Gene_View]  chr6:36916039-36932613 [Contig_View]  PI16 [Vega]
ICGC DataPortalENSG00000164530
AceView (NCBI)PI16
Genatlas (Paris)PI16
SOURCE (Princeton)PI16
Genomic and cartography
GoldenPath hg19 (UCSC)PI16  -     chr6:36916039-36932613 +  6p21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PI16  -     6p21.2   [Description]    (hg38-Dec_2013)
EnsemblPI16 - 6p21.2 [CytoView hg19]  PI16 - 6p21.2 [CytoView hg38]
Mapping of homologs : NCBIPI16 [Mapview hg19]  PI16 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK075470 AK124589 AK302193 AK303928 AK312785
RefSeq transcript (Entrez)NM_001199159 NM_153370
RefSeq genomic (Entrez)NC_000006 NC_018917 NT_007592 NW_004929326
Consensus coding sequences : CCDS (NCBI)PI16
Cluster EST : UnigeneHs.25391 [ NCBI ]
CGAP (NCI)Hs.25391
Alternative Splicing : Fast-db (Paris)GSHG0025690
Alternative Splicing GalleryENSG00000164530
Gene ExpressionPI16 [ NCBI-GEO ]     PI16 [ SEEK ]   PI16 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UXB8 (Uniprot)
NextProtQ6UXB8  [Medical]
With graphics : InterProQ6UXB8
Splice isoforms : SwissVarQ6UXB8 (Swissvar)
Domaine pattern : Prosite (Expaxy)CRISP_1 (PS01009)    CRISP_2 (PS01010)   
Domains : Interpro (EBI)Allrgn_V5/Tpx1    Allrgn_V5/Tpx1_CS    CAP_domain   
Related proteins : CluSTrQ6UXB8
Domain families : Pfam (Sanger)CAP (PF00188)   
Domain families : Pfam (NCBI)pfam00188   
Domain families : Smart (EMBL)SCP (SM00198)  
DMDM Disease mutations221476
Blocks (Seattle)Q6UXB8
Human Protein AtlasENSG00000164530
Peptide AtlasQ6UXB8
IPIIPI00301143   IPI00845506   IPI01015788   
Protein Interaction databases
IntAct (EBI)Q6UXB8
Ontologies - Pathways
Ontology : AmiGOextracellular space  negative regulation of peptidase activity  integral component of membrane  peptidase inhibitor activity  negative regulation of cell growth involved in cardiac muscle cell development  extracellular exosome  
Ontology : EGO-EBIextracellular space  negative regulation of peptidase activity  integral component of membrane  peptidase inhibitor activity  negative regulation of cell growth involved in cardiac muscle cell development  extracellular exosome  
Protein Interaction DatabasePI16
DoCM (Curated mutations)PI16
Wikipedia pathwaysPI16
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerPI16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PI16
Exome Variant ServerPI16
SNP (GeneSNP Utah)PI16
SNP : HGBasePI16
Genetic variants : HAPMAPPI16
Genomic Variants (DGV)PI16 [DGVbeta]
ICGC Data PortalENSG00000164530 
Somatic Mutations in Cancer : COSMICPI16 
CONAN: Copy Number AnalysisPI16 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
DECIPHER (Syndromes)6:36916039-36932613
Mutations and Diseases : HGMDPI16
NextProtQ6UXB8 [Medical]
Disease Genetic AssociationPI16
Huge Navigator PI16 [HugePedia]  PI16 [HugeCancerGEM]
snp3D : Map Gene to Disease221476
DGIdb (Drug Gene Interaction db)PI16
General knowledge
Homologs : HomoloGenePI16
Homology/Alignments : Family Browser (UCSC)PI16
Phylogenetic Trees/Animal Genes : TreeFamPI16
Chemical/Protein Interactions : CTD221476
Chemical/Pharm GKB GenePA134867616
Clinical trialPI16
Cancer Resource (Charite)ENSG00000164530
Other databases
PubMed10 Pubmed reference(s) in Entrez
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI


Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 16:54:44 CET 2015

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