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PIDD1 (p53-induced death domain protein 1)

Identity

Alias_namesLRDD
PIDD
leucine-rich repeats and death domain containing
p53-induced death domain protein
Alias_symbol (synonym)MGC16925
DKFZp434D229
Other alias
HGNC (Hugo) PIDD1
LocusID (NCBI) 55367
Atlas_Id 52253
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 799179 and ends at 805250 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PIDD1   16491
Cards
Entrez_Gene (NCBI)PIDD1  55367  p53-induced death domain protein 1
AliasesLRDD; PIDD
GeneCards (Weizmann)PIDD1
Ensembl hg19 (Hinxton)ENSG00000177595 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000177595 [Gene_View]  chr11:799179-805250 [Contig_View]  PIDD1 [Vega]
ICGC DataPortalENSG00000177595
TCGA cBioPortalPIDD1
AceView (NCBI)PIDD1
Genatlas (Paris)PIDD1
WikiGenes55367
SOURCE (Princeton)PIDD1
Genetics Home Reference (NIH)PIDD1
Genomic and cartography
GoldenPath hg38 (UCSC)PIDD1  -     chr11:799179-805250 -  11p15.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PIDD1  -     11p15.5   [Description]    (hg19-Feb_2009)
EnsemblPIDD1 - 11p15.5 [CytoView hg19]  PIDD1 - 11p15.5 [CytoView hg38]
Mapping of homologs : NCBIPIDD1 [Mapview hg19]  PIDD1 [Mapview hg38]
OMIM605247   
Gene and transcription
Genbank (Entrez)AB208832 AB208949 AB209529 AF229178 AF274972
RefSeq transcript (Entrez)NM_018494 NM_145886 NM_145887
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PIDD1
Cluster EST : UnigeneHs.592290 [ NCBI ]
CGAP (NCI)Hs.592290
Alternative Splicing GalleryENSG00000177595
Gene ExpressionPIDD1 [ NCBI-GEO ]   PIDD1 [ EBI - ARRAY_EXPRESS ]   PIDD1 [ SEEK ]   PIDD1 [ MEM ]
Gene Expression Viewer (FireBrowse)PIDD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55367
GTEX Portal (Tissue expression)PIDD1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HB75   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HB75  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HB75
Splice isoforms : SwissVarQ9HB75
PhosPhoSitePlusQ9HB75
Domaine pattern : Prosite (Expaxy)DEATH_DOMAIN (PS50017)    LRR (PS51450)    ZU5 (PS51145)   
Domains : Interpro (EBI)DEATH-like_dom    Death_domain    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    Peptidase_S68_pidd    ZU5_dom   
Domain families : Pfam (Sanger)Death (PF00531)    LRR_8 (PF13855)    Peptidase_S68 (PF10461)    ZU5 (PF00791)   
Domain families : Pfam (NCBI)pfam00531    pfam13855    pfam10461    pfam00791   
Domain families : Smart (EMBL)DEATH (SM00005)  LRR_TYP (SM00369)  
Conserved Domain (NCBI)PIDD1
DMDM Disease mutations55367
Blocks (Seattle)PIDD1
PDB (SRS)2OF5   
PDB (PDBSum)2OF5   
PDB (IMB)2OF5   
PDB (RSDB)2OF5   
Structural Biology KnowledgeBase2OF5   
SCOP (Structural Classification of Proteins)2OF5   
CATH (Classification of proteins structures)2OF5   
SuperfamilyQ9HB75
Human Protein AtlasENSG00000177595
Peptide AtlasQ9HB75
HPRD11284
IPIIPI00396438   IPI00171737   IPI00749289   IPI00760720   IPI00760854   IPI00555732   IPI00761169   IPI00975544   
Protein Interaction databases
DIP (DOE-UCLA)Q9HB75
IntAct (EBI)Q9HB75
FunCoupENSG00000177595
BioGRIDPIDD1
STRING (EMBL)PIDD1
ZODIACPIDD1
Ontologies - Pathways
QuickGOQ9HB75
Ontology : AmiGOdeath receptor binding  protein binding  nucleus  nucleoplasm  cytoplasm  Golgi apparatus  cytosol  cytosol  apoptotic process  activation of cysteine-type endopeptidase activity involved in apoptotic process  cellular response to DNA damage stimulus  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  signal transduction  regulation of apoptotic process  positive regulation of apoptotic process  negative regulation of apoptotic process  positive regulation of NF-kappaB transcription factor activity  positive regulation of extrinsic apoptotic signaling pathway via death domain receptors  
Ontology : EGO-EBIdeath receptor binding  protein binding  nucleus  nucleoplasm  cytoplasm  Golgi apparatus  cytosol  cytosol  apoptotic process  activation of cysteine-type endopeptidase activity involved in apoptotic process  cellular response to DNA damage stimulus  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  signal transduction  regulation of apoptotic process  positive regulation of apoptotic process  negative regulation of apoptotic process  positive regulation of NF-kappaB transcription factor activity  positive regulation of extrinsic apoptotic signaling pathway via death domain receptors  
NDEx NetworkPIDD1
Atlas of Cancer Signalling NetworkPIDD1
Wikipedia pathwaysPIDD1
Orthology - Evolution
OrthoDB55367
GeneTree (enSembl)ENSG00000177595
Phylogenetic Trees/Animal Genes : TreeFamPIDD1
HOVERGENQ9HB75
HOGENOMQ9HB75
Homologs : HomoloGenePIDD1
Homology/Alignments : Family Browser (UCSC)PIDD1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPIDD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIDD1
dbVarPIDD1
ClinVarPIDD1
1000_GenomesPIDD1 
Exome Variant ServerPIDD1
ExAC (Exome Aggregation Consortium)PIDD1 (select the gene name)
Genetic variants : HAPMAP55367
Genomic Variants (DGV)PIDD1 [DGVbeta]
DECIPHERPIDD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPIDD1 
Mutations
ICGC Data PortalPIDD1 
TCGA Data PortalPIDD1 
Broad Tumor PortalPIDD1
OASIS PortalPIDD1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPIDD1
BioMutasearch PIDD1
DgiDB (Drug Gene Interaction Database)PIDD1
DoCM (Curated mutations)PIDD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PIDD1 (select a term)
intoGenPIDD1
Cancer3DPIDD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605247   
Orphanet
MedgenPIDD1
Genetic Testing Registry PIDD1
NextProtQ9HB75 [Medical]
TSGene55367
GENETestsPIDD1
Target ValidationPIDD1
Huge Navigator PIDD1 [HugePedia]
snp3D : Map Gene to Disease55367
BioCentury BCIQPIDD1
ClinGenPIDD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55367
Chemical/Pharm GKB GenePA30445
Clinical trialPIDD1
Miscellaneous
canSAR (ICR)PIDD1 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePIDD1
EVEXPIDD1
GoPubMedPIDD1
iHOPPIDD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:10:38 CEST 2017

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