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PIF1 (PIF1 5'-to-3' DNA helicase)

Identity

Alias_namesC15orf20
chromosome 15 open reading frame 20
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
Alias_symbol (synonym)FLJ22692
Other aliasPIF
HGNC (Hugo) PIF1
LocusID (NCBI) 80119
Atlas_Id 52460
Location 15q22.31  [Link to chromosome band 15q22]
Location_base_pair Starts at 64815630 and ends at 64825668 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PIF1   26220
Cards
Entrez_Gene (NCBI)PIF1  80119  PIF1 5'-to-3' DNA helicase
AliasesC15orf20; PIF
GeneCards (Weizmann)PIF1
Ensembl hg19 (Hinxton)ENSG00000140451 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140451 [Gene_View]  chr15:64815630-64825668 [Contig_View]  PIF1 [Vega]
ICGC DataPortalENSG00000140451
TCGA cBioPortalPIF1
AceView (NCBI)PIF1
Genatlas (Paris)PIF1
WikiGenes80119
SOURCE (Princeton)PIF1
Genetics Home Reference (NIH)PIF1
Genomic and cartography
GoldenPath hg38 (UCSC)PIF1  -     chr15:64815630-64825668 -  15q22.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PIF1  -     15q22.31   [Description]    (hg19-Feb_2009)
EnsemblPIF1 - 15q22.31 [CytoView hg19]  PIF1 - 15q22.31 [CytoView hg38]
Mapping of homologs : NCBIPIF1 [Mapview hg19]  PIF1 [Mapview hg38]
OMIM610953   
Gene and transcription
Genbank (Entrez)AB185926 AB185927 AF108138 AK026345 AW170361
RefSeq transcript (Entrez)NM_001286496 NM_001286497 NM_001286499 NM_025049
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PIF1
Cluster EST : UnigeneHs.112160 [ NCBI ]
CGAP (NCI)Hs.112160
Alternative Splicing GalleryENSG00000140451
Gene ExpressionPIF1 [ NCBI-GEO ]   PIF1 [ EBI - ARRAY_EXPRESS ]   PIF1 [ SEEK ]   PIF1 [ MEM ]
Gene Expression Viewer (FireBrowse)PIF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80119
GTEX Portal (Tissue expression)PIF1
Human Protein AtlasENSG00000140451-PIF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H611   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H611  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H611
Splice isoforms : SwissVarQ9H611
PhosPhoSitePlusQ9H611
Domains : Interpro (EBI)DNA_helicase    DNA_helicase_pif1-like    P-loop_NTPase   
Domain families : Pfam (Sanger)Herpes_Helicase (PF02689)    PIF1 (PF05970)   
Domain families : Pfam (NCBI)pfam02689    pfam05970   
Conserved Domain (NCBI)PIF1
DMDM Disease mutations80119
Blocks (Seattle)PIF1
PDB (SRS)5FHH   
PDB (PDBSum)5FHH   
PDB (IMB)5FHH   
PDB (RSDB)5FHH   
Structural Biology KnowledgeBase5FHH   
SCOP (Structural Classification of Proteins)5FHH   
CATH (Classification of proteins structures)5FHH   
SuperfamilyQ9H611
Human Protein Atlas [tissue]ENSG00000140451-PIF1 [tissue]
Peptide AtlasQ9H611
HPRD10715
IPIIPI00793711   IPI00746514   IPI00017925   
Protein Interaction databases
DIP (DOE-UCLA)Q9H611
IntAct (EBI)Q9H611
FunCoupENSG00000140451
BioGRIDPIF1
STRING (EMBL)PIF1
ZODIACPIF1
Ontologies - Pathways
QuickGOQ9H611
Ontology : AmiGOmitochondrial genome maintenance  magnesium ion binding  telomere maintenance  nuclear chromosome, telomeric region  ATP binding  replication fork  mitochondrion  DNA replication  DNA repair  DNA recombination  telomerase inhibitor activity  single-stranded DNA-dependent ATP-dependent DNA helicase activity  regulation of telomere maintenance  negative regulation of telomere maintenance via telomerase  negative regulation of telomere maintenance via telomerase  DNA duplex unwinding  ATP-dependent 5'-3' DNA/RNA helicase activity  telomeric DNA binding  ATP-dependent 5'-3' DNA helicase activity  G-quadruplex DNA unwinding  negative regulation of telomerase activity  
Ontology : EGO-EBImitochondrial genome maintenance  magnesium ion binding  telomere maintenance  nuclear chromosome, telomeric region  ATP binding  replication fork  mitochondrion  DNA replication  DNA repair  DNA recombination  telomerase inhibitor activity  single-stranded DNA-dependent ATP-dependent DNA helicase activity  regulation of telomere maintenance  negative regulation of telomere maintenance via telomerase  negative regulation of telomere maintenance via telomerase  DNA duplex unwinding  ATP-dependent 5'-3' DNA/RNA helicase activity  telomeric DNA binding  ATP-dependent 5'-3' DNA helicase activity  G-quadruplex DNA unwinding  negative regulation of telomerase activity  
NDEx NetworkPIF1
Atlas of Cancer Signalling NetworkPIF1
Wikipedia pathwaysPIF1
Orthology - Evolution
OrthoDB80119
GeneTree (enSembl)ENSG00000140451
Phylogenetic Trees/Animal Genes : TreeFamPIF1
HOVERGENQ9H611
HOGENOMQ9H611
Homologs : HomoloGenePIF1
Homology/Alignments : Family Browser (UCSC)PIF1
Gene fusions - Rearrangements
Tumor Fusion PortalPIF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPIF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIF1
dbVarPIF1
ClinVarPIF1
1000_GenomesPIF1 
Exome Variant ServerPIF1
ExAC (Exome Aggregation Consortium)ENSG00000140451
GNOMAD BrowserENSG00000140451
Genetic variants : HAPMAP80119
Genomic Variants (DGV)PIF1 [DGVbeta]
DECIPHERPIF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPIF1 
Mutations
ICGC Data PortalPIF1 
TCGA Data PortalPIF1 
Broad Tumor PortalPIF1
OASIS PortalPIF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPIF1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPIF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PIF1
DgiDB (Drug Gene Interaction Database)PIF1
DoCM (Curated mutations)PIF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PIF1 (select a term)
intoGenPIF1
Cancer3DPIF1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610953   
Orphanet
DisGeNETPIF1
MedgenPIF1
Genetic Testing Registry PIF1
NextProtQ9H611 [Medical]
TSGene80119
GENETestsPIF1
Target ValidationPIF1
Huge Navigator PIF1 [HugePedia]
snp3D : Map Gene to Disease80119
BioCentury BCIQPIF1
ClinGenPIF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80119
Chemical/Pharm GKB GenePA162399475
Clinical trialPIF1
Miscellaneous
canSAR (ICR)PIF1 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePIF1
EVEXPIF1
GoPubMedPIF1
iHOPPIF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:28:43 CET 2017

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