Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PIGA (phosphatidylinositol glycan anchor biosynthesis, class A)

Identity

Other namesGPI3
MCAHS2
PIG-A
PNH1
HGNC (Hugo) PIGA
LocusID (NCBI) 5277
Location Xp22.2
Location_base_pair Starts at 15337573 and ends at 15353676 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PIGA   8957
Cards
Entrez_Gene (NCBI)PIGA  5277  phosphatidylinositol glycan anchor biosynthesis, class A
GeneCards (Weizmann)PIGA
Ensembl (Hinxton)ENSG00000165195 [Gene_View]  chrX:15337573-15353676 [Contig_View]  PIGA [Vega]
ICGC DataPortalENSG00000165195
cBioPortalPIGA
AceView (NCBI)PIGA
Genatlas (Paris)PIGA
WikiGenes5277
SOURCE (Princeton)NM_002641 NM_020472 NM_020473
Genomic and cartography
GoldenPath (UCSC)PIGA  -  Xp22.2   chrX:15337573-15353676 -  Xp22.2   [Description]    (hg19-Feb_2009)
EnsemblPIGA - Xp22.2 [CytoView]
Mapping of homologs : NCBIPIGA [Mapview]
OMIM300818   300868   311770   
Gene and transcription
Genbank (Entrez)AK098047 AK290497 AK303538 AK304144 AK315063
RefSeq transcript (Entrez)NM_002641 NM_020472 NM_020473
RefSeq genomic (Entrez)AC_000155 NC_000023 NC_018934 NG_009786 NT_167197 NW_001842360 NW_004929438
Consensus coding sequences : CCDS (NCBI)PIGA
Cluster EST : UnigeneHs.137154 [ NCBI ]
CGAP (NCI)Hs.137154
Alternative Splicing : Fast-db (Paris)GSHG0031985
Alternative Splicing GalleryENSG00000165195
Gene ExpressionPIGA [ NCBI-GEO ]     PIGA [ SEEK ]   PIGA [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP37287 (Uniprot)
NextProtP37287  [Medical]
With graphics : InterProP37287
Splice isoforms : SwissVarP37287 (Swissvar)
Catalytic activity : Enzyme2.4.1.198 [ Enzyme-Expasy ]   2.4.1.1982.4.1.198 [ IntEnz-EBI ]   2.4.1.198 [ BRENDA ]   2.4.1.198 [ KEGG ]   
Domains : Interpro (EBI)Glyco_trans_1 [organisation]   PIGA_GPI_anchor_biosynthesis [organisation]  
Related proteins : CluSTrP37287
Domain families : Pfam (Sanger)Glycos_transf_1 (PF00534)    PIGA (PF08288)   
Domain families : Pfam (NCBI)pfam00534    pfam08288   
DMDM Disease mutations5277
Blocks (Seattle)P37287
Human Protein AtlasENSG00000165195 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP37287
HPRD02410
IPIIPI00020966   IPI00220404   IPI01011556   IPI00942148   
Protein Interaction databases
DIP (DOE-UCLA)P37287
IntAct (EBI)P37287
FunCoupENSG00000165195
BioGRIDPIGA
InParanoidP37287
Interologous Interaction database P37287
IntegromeDBPIGA
STRING (EMBL)PIGA
Ontologies - Pathways
Ontology : AmiGOglycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex  protein binding  endoplasmic reticulum membrane  endoplasmic reticulum membrane  C-terminal protein lipidation  GPI anchor biosynthetic process  UDP-glycosyltransferase activity  positive regulation of metabolic process  membrane  integral component of membrane  preassembly of GPI anchor in ER membrane  phosphatidylinositol N-acetylglucosaminyltransferase activity  post-translational protein modification  cellular protein metabolic process  
Ontology : EGO-EBIglycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex  protein binding  endoplasmic reticulum membrane  endoplasmic reticulum membrane  C-terminal protein lipidation  GPI anchor biosynthetic process  UDP-glycosyltransferase activity  positive regulation of metabolic process  membrane  integral component of membrane  preassembly of GPI anchor in ER membrane  phosphatidylinositol N-acetylglucosaminyltransferase activity  post-translational protein modification  cellular protein metabolic process  
Pathways : KEGGGlycosylphosphatidylinositol(GPI)-anchor biosynthesis   
Protein Interaction DatabasePIGA
Wikipedia pathwaysPIGA
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PIGA
snp3D : Map Gene to Disease5277
SNP (GeneSNP Utah)PIGA
SNP : HGBasePIGA
Genetic variants : HAPMAPPIGA
Exome VariantPIGA
1000_GenomesPIGA 
ICGC programENSG00000165195 
Somatic Mutations in Cancer : COSMICPIGA 
CONAN: Copy Number AnalysisPIGA 
Mutations and Diseases : HGMDPIGA
Genomic VariantsPIGA  PIGA [DGVbeta]
dbVarPIGA
ClinVarPIGA
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM300818    300868    311770   
MedgenPIGA
GENETestsPIGA
Disease Genetic AssociationPIGA
Huge Navigator PIGA [HugePedia]  PIGA [HugeCancerGEM]
General knowledge
Homologs : HomoloGenePIGA
Homology/Alignments : Family Browser (UCSC)PIGA
Phylogenetic Trees/Animal Genes : TreeFamPIGA
Chemical/Protein Interactions : CTD5277
Chemical/Pharm GKB GenePA33288
Clinical trialPIGA
Cancer Resource (Charite)ENSG00000165195
Other databases
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
CoreMinePIGA
iHOPPIGA
OncoSearchPIGA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 14:09:46 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.