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PIGB (phosphatidylinositol glycan anchor biosynthesis class B)

Identity

Alias_namesphosphatidylinositol glycan
Other aliasGPI-MT-III
PIG-B
HGNC (Hugo) PIGB
LocusID (NCBI) 9488
Atlas_Id 47194
Location 15q21.3  [Link to chromosome band 15q21]
Location_base_pair Starts at 55318935 and ends at 55355648 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LARS (5q32) / PIGB (15q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PIGB   8959
Cards
Entrez_Gene (NCBI)PIGB  9488  phosphatidylinositol glycan anchor biosynthesis class B
AliasesGPI-MT-III; PIG-B
GeneCards (Weizmann)PIGB
Ensembl hg19 (Hinxton)ENSG00000069943 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000069943 [Gene_View]  chr15:55318935-55355648 [Contig_View]  PIGB [Vega]
ICGC DataPortalENSG00000069943
TCGA cBioPortalPIGB
AceView (NCBI)PIGB
Genatlas (Paris)PIGB
WikiGenes9488
SOURCE (Princeton)PIGB
Genetics Home Reference (NIH)PIGB
Genomic and cartography
GoldenPath hg38 (UCSC)PIGB  -     chr15:55318935-55355648 +  15q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PIGB  -     15q21.3   [Description]    (hg19-Feb_2009)
EnsemblPIGB - 15q21.3 [CytoView hg19]  PIGB - 15q21.3 [CytoView hg38]
Mapping of homologs : NCBIPIGB [Mapview hg19]  PIGB [Mapview hg38]
OMIM604122   
Gene and transcription
Genbank (Entrez)AK093138 AK223330 AK293666 AK314706 BC017711
RefSeq transcript (Entrez)NM_004855
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PIGB
Cluster EST : UnigeneHs.612814 [ NCBI ]
CGAP (NCI)Hs.612814
Alternative Splicing GalleryENSG00000069943
Gene ExpressionPIGB [ NCBI-GEO ]   PIGB [ EBI - ARRAY_EXPRESS ]   PIGB [ SEEK ]   PIGB [ MEM ]
Gene Expression Viewer (FireBrowse)PIGB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9488
GTEX Portal (Tissue expression)PIGB
Human Protein AtlasENSG00000069943-PIGB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92521   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92521  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92521
Splice isoforms : SwissVarQ92521
Catalytic activity : Enzyme2.4.1.- [ Enzyme-Expasy ]   2.4.1.-2.4.1.- [ IntEnz-EBI ]   2.4.1.- [ BRENDA ]   2.4.1.- [ KEGG ]   
PhosPhoSitePlusQ92521
Domains : Interpro (EBI)GPI_mannosylTrfase   
Domain families : Pfam (Sanger)Glyco_transf_22 (PF03901)   
Domain families : Pfam (NCBI)pfam03901   
Conserved Domain (NCBI)PIGB
DMDM Disease mutations9488
Blocks (Seattle)PIGB
SuperfamilyQ92521
Human Protein Atlas [tissue]ENSG00000069943-PIGB [tissue]
Peptide AtlasQ92521
HPRD04988
IPIIPI00145121   IPI01011779   
Protein Interaction databases
DIP (DOE-UCLA)Q92521
IntAct (EBI)Q92521
FunCoupENSG00000069943
BioGRIDPIGB
STRING (EMBL)PIGB
ZODIACPIGB
Ontologies - Pathways
QuickGOQ92521
Ontology : AmiGOmannosyltransferase activity  glycolipid mannosyltransferase activity  endoplasmic reticulum membrane  endoplasmic reticulum membrane  GPI anchor biosynthetic process  integral component of membrane  preassembly of GPI anchor in ER membrane  mannosylation  
Ontology : EGO-EBImannosyltransferase activity  glycolipid mannosyltransferase activity  endoplasmic reticulum membrane  endoplasmic reticulum membrane  GPI anchor biosynthetic process  integral component of membrane  preassembly of GPI anchor in ER membrane  mannosylation  
Pathways : KEGGGlycosylphosphatidylinositol(GPI)-anchor biosynthesis   
NDEx NetworkPIGB
Atlas of Cancer Signalling NetworkPIGB
Wikipedia pathwaysPIGB
Orthology - Evolution
OrthoDB9488
GeneTree (enSembl)ENSG00000069943
Phylogenetic Trees/Animal Genes : TreeFamPIGB
HOVERGENQ92521
HOGENOMQ92521
Homologs : HomoloGenePIGB
Homology/Alignments : Family Browser (UCSC)PIGB
Gene fusions - Rearrangements
Tumor Fusion PortalPIGB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPIGB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIGB
dbVarPIGB
ClinVarPIGB
1000_GenomesPIGB 
Exome Variant ServerPIGB
ExAC (Exome Aggregation Consortium)ENSG00000069943
GNOMAD BrowserENSG00000069943
Genetic variants : HAPMAP9488
Genomic Variants (DGV)PIGB [DGVbeta]
DECIPHERPIGB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPIGB 
Mutations
ICGC Data PortalPIGB 
TCGA Data PortalPIGB 
Broad Tumor PortalPIGB
OASIS PortalPIGB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPIGB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPIGB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PIGB
DgiDB (Drug Gene Interaction Database)PIGB
DoCM (Curated mutations)PIGB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PIGB (select a term)
intoGenPIGB
Cancer3DPIGB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604122   
Orphanet
DisGeNETPIGB
MedgenPIGB
Genetic Testing Registry PIGB
NextProtQ92521 [Medical]
TSGene9488
GENETestsPIGB
Target ValidationPIGB
Huge Navigator PIGB [HugePedia]
snp3D : Map Gene to Disease9488
BioCentury BCIQPIGB
ClinGenPIGB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9488
Chemical/Pharm GKB GenePA33290
Clinical trialPIGB
Miscellaneous
canSAR (ICR)PIGB (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePIGB
EVEXPIGB
GoPubMedPIGB
iHOPPIGB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:28:43 CET 2017

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