Atlas of Genetics and Cytogenetics in Oncology and Haematology

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PIGC (phosphatidylinositol glycan anchor biosynthesis class C)

Identity

Alias_namesphosphatidylinositol glycan
Other aliasGPI2
GPIBD16
MRT62
HGNC (Hugo) PIGC
LocusID (NCBI) 5279
Atlas_Id 47350
Location 1q24.3  [Link to chromosome band 1q24]
Location_base_pair Starts at 172441457 and ends at 172444090 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GGT7 (20q11.22) / PIGC (1q24.3)PIGC (1q24.3) / MTHFD1 (14q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PIGC   8960
Cards
Entrez_Gene (NCBI)PIGC  5279  phosphatidylinositol glycan anchor biosynthesis class C
AliasesGPI2; GPIBD16; MRT62
GeneCards (Weizmann)PIGC
Ensembl hg19 (Hinxton)ENSG00000135845 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135845 [Gene_View]ENSG00000135845 [Sequence]  chr1:172441457-172444090 [Contig_View]  PIGC [Vega]
ICGC DataPortalENSG00000135845
TCGA cBioPortalPIGC
AceView (NCBI)PIGC
Genatlas (Paris)PIGC
WikiGenes5279
SOURCE (Princeton)PIGC
Genetics Home Reference (NIH)PIGC
Genomic and cartography
GoldenPath hg38 (UCSC)PIGC  -     chr1:172441457-172444090 -  1q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PIGC  -     1q24.3   [Description]    (hg19-Feb_2009)
EnsemblPIGC - 1q24.3 [CytoView hg19]  PIGC - 1q24.3 [CytoView hg38]
Mapping of homologs : NCBIPIGC [Mapview hg19]  PIGC [Mapview hg38]
OMIM601730   617816   
Gene and transcription
Genbank (Entrez)AA372370 AK308201 BC006539 BC063473 BG106700
RefSeq transcript (Entrez)NM_002642 NM_153747
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PIGC
Cluster EST : UnigeneHs.188456 [ NCBI ]
CGAP (NCI)Hs.188456
Alternative Splicing GalleryENSG00000135845
Gene ExpressionPIGC [ NCBI-GEO ]   PIGC [ EBI - ARRAY_EXPRESS ]   PIGC [ SEEK ]   PIGC [ MEM ]
Gene Expression Viewer (FireBrowse)PIGC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5279
GTEX Portal (Tissue expression)PIGC
Human Protein AtlasENSG00000135845-PIGC [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92535   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92535  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92535
Splice isoforms : SwissVarQ92535
Catalytic activity : Enzyme2.4.1.198 [ Enzyme-Expasy ]   2.4.1.1982.4.1.198 [ IntEnz-EBI ]   2.4.1.198 [ BRENDA ]   2.4.1.198 [ KEGG ]   
PhosPhoSitePlusQ92535
Domains : Interpro (EBI)Plno_GlcNAc_GPI2   
Domain families : Pfam (Sanger)GPI2 (PF06432)   
Domain families : Pfam (NCBI)pfam06432   
Conserved Domain (NCBI)PIGC
DMDM Disease mutations5279
Blocks (Seattle)PIGC
SuperfamilyQ92535
Human Protein Atlas [tissue]ENSG00000135845-PIGC [tissue]
Peptide AtlasQ92535
HPRD03433
IPIIPI00021948   IPI00023652   
Protein Interaction databases
DIP (DOE-UCLA)Q92535
IntAct (EBI)Q92535
FunCoupENSG00000135845
BioGRIDPIGC
STRING (EMBL)PIGC
ZODIACPIGC
Ontologies - Pathways
QuickGOQ92535
Ontology : AmiGOglycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex  catalytic activity  endoplasmic reticulum membrane  GPI anchor biosynthetic process  integral component of membrane  preassembly of GPI anchor in ER membrane  phosphatidylinositol N-acetylglucosaminyltransferase activity  
Ontology : EGO-EBIglycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex  catalytic activity  endoplasmic reticulum membrane  GPI anchor biosynthetic process  integral component of membrane  preassembly of GPI anchor in ER membrane  phosphatidylinositol N-acetylglucosaminyltransferase activity  
Pathways : KEGGGlycosylphosphatidylinositol(GPI)-anchor biosynthesis    Glycan structures - biosynthesis 2   
NDEx NetworkPIGC
Atlas of Cancer Signalling NetworkPIGC
Wikipedia pathwaysPIGC
Orthology - Evolution
OrthoDB5279
GeneTree (enSembl)ENSG00000135845
Phylogenetic Trees/Animal Genes : TreeFamPIGC
HOVERGENQ92535
HOGENOMQ92535
Homologs : HomoloGenePIGC
Homology/Alignments : Family Browser (UCSC)PIGC
Gene fusions - Rearrangements
Fusion : QuiverPIGC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPIGC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIGC
dbVarPIGC
ClinVarPIGC
1000_GenomesPIGC 
Exome Variant ServerPIGC
ExAC (Exome Aggregation Consortium)ENSG00000135845
GNOMAD BrowserENSG00000135845
Genetic variants : HAPMAP5279
Genomic Variants (DGV)PIGC [DGVbeta]
DECIPHERPIGC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPIGC 
Mutations
ICGC Data PortalPIGC 
TCGA Data PortalPIGC 
Broad Tumor PortalPIGC
OASIS PortalPIGC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPIGC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPIGC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PIGC
DgiDB (Drug Gene Interaction Database)PIGC
DoCM (Curated mutations)PIGC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PIGC (select a term)
intoGenPIGC
Cancer3DPIGC(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601730    617816   
Orphanet
DisGeNETPIGC
MedgenPIGC
Genetic Testing Registry PIGC
NextProtQ92535 [Medical]
TSGene5279
GENETestsPIGC
Target ValidationPIGC
Huge Navigator PIGC [HugePedia]
snp3D : Map Gene to Disease5279
BioCentury BCIQPIGC
ClinGenPIGC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5279
Chemical/Pharm GKB GenePA33291
Clinical trialPIGC
Miscellaneous
canSAR (ICR)PIGC (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePIGC
EVEXPIGC
GoPubMedPIGC
iHOPPIGC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jun 21 17:08:06 CEST 2018
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