Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PIGK (phosphatidylinositol glycan anchor biosynthesis class K)

Identity

Alias (NCBI)GPI8
NEDHCAS
HGNC (Hugo) PIGK
HGNC Alias symbhGPI8
GPI8
HGNC Alias nameGPI transamidase subunit
HGNC Previous namephosphatidylinositol glycan, class K
LocusID (NCBI) 10026
Atlas_Id 47469
Location 1p31.1  [Link to chromosome band 1p31]
Location_base_pair Starts at 77088990 and ends at 77219430 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PIGK (1p31.1) / KIF21A (12q12)PIGK (1p31.1) / SPATA6 (1p33)PIGK (1p31.1) / ST6GALNAC3 (1p31.1)
PIGK 1p31.1 / ST6GALNAC3 1p31.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PIGK   8965
Cards
Entrez_Gene (NCBI)PIGK    phosphatidylinositol glycan anchor biosynthesis class K
AliasesGPI8; NEDHCAS
GeneCards (Weizmann)PIGK
Ensembl hg19 (Hinxton)ENSG00000142892 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142892 [Gene_View]  ENSG00000142892 [Sequence]  chr1:77088990-77219430 [Contig_View]  PIGK [Vega]
ICGC DataPortalENSG00000142892
TCGA cBioPortalPIGK
AceView (NCBI)PIGK
Genatlas (Paris)PIGK
SOURCE (Princeton)PIGK
Genetics Home Reference (NIH)PIGK
Genomic and cartography
GoldenPath hg38 (UCSC)PIGK  -     chr1:77088990-77219430 -  1p31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PIGK  -     1p31.1   [Description]    (hg19-Feb_2009)
GoldenPathPIGK - 1p31.1 [CytoView hg19]  PIGK - 1p31.1 [CytoView hg38]
ImmunoBaseENSG00000142892
Genome Data Viewer NCBIPIGK [Mapview hg19]  
OMIM605087   618879   
Gene and transcription
Genbank (Entrez)AF022913 AK055071 AK304340 AK313015 BC020737
RefSeq transcript (Entrez)NM_005482
Consensus coding sequences : CCDS (NCBI)PIGK
Gene ExpressionPIGK [ NCBI-GEO ]   PIGK [ EBI - ARRAY_EXPRESS ]   PIGK [ SEEK ]   PIGK [ MEM ]
Gene Expression Viewer (FireBrowse)PIGK [ Firebrowse - Broad ]
GenevisibleExpression of PIGK in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10026
GTEX Portal (Tissue expression)PIGK
Human Protein AtlasENSG00000142892-PIGK [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92643   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92643  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92643
Catalytic activity : Enzyme3.-.-.- [ Enzyme-Expasy ]   3.-.-.-3.-.-.- [ IntEnz-EBI ]   3.-.-.- [ BRENDA ]   3.-.-.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ92643
Domains : Interpro (EBI)GPI_transamidase    Peptidase_C13   
Domain families : Pfam (Sanger)Peptidase_C13 (PF01650)   
Domain families : Pfam (NCBI)pfam01650   
Conserved Domain (NCBI)PIGK
SuperfamilyQ92643
AlphaFold pdb e-kbQ92643   
Human Protein Atlas [tissue]ENSG00000142892-PIGK [tissue]
HPRD05474
Protein Interaction databases
DIP (DOE-UCLA)Q92643
IntAct (EBI)Q92643
BioGRIDPIGK
STRING (EMBL)PIGK
ZODIACPIGK
Ontologies - Pathways
QuickGOQ92643
Ontology : AmiGOprotein disulfide isomerase activity  GPI-anchor transamidase activity  GPI-anchor transamidase activity  protein binding  endoplasmic reticulum membrane  proteolysis  membrane  attachment of GPI anchor to protein  attachment of GPI anchor to protein  GPI anchor binding  protein localization to cell surface  GPI-anchor transamidase complex  GPI-anchor transamidase complex  GPI-anchor transamidase complex  
Ontology : EGO-EBIprotein disulfide isomerase activity  GPI-anchor transamidase activity  GPI-anchor transamidase activity  protein binding  endoplasmic reticulum membrane  proteolysis  membrane  attachment of GPI anchor to protein  attachment of GPI anchor to protein  GPI anchor binding  protein localization to cell surface  GPI-anchor transamidase complex  GPI-anchor transamidase complex  GPI-anchor transamidase complex  
Pathways : KEGGGlycosylphosphatidylinositol(GPI)-anchor biosynthesis   
NDEx NetworkPIGK
Atlas of Cancer Signalling NetworkPIGK
Wikipedia pathwaysPIGK
Orthology - Evolution
OrthoDB10026
GeneTree (enSembl)ENSG00000142892
Phylogenetic Trees/Animal Genes : TreeFamPIGK
Homologs : HomoloGenePIGK
Homology/Alignments : Family Browser (UCSC)PIGK
Gene fusions - Rearrangements
Fusion : MitelmanPIGK/SPATA6 [1p31.1/1p33]  
Fusion : MitelmanPIGK/ST6GALNAC3 [1p31.1/1p31.1]  
Fusion : QuiverPIGK
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPIGK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIGK
dbVarPIGK
ClinVarPIGK
MonarchPIGK
1000_GenomesPIGK 
Exome Variant ServerPIGK
GNOMAD BrowserENSG00000142892
Varsome BrowserPIGK
ACMGPIGK variants
VarityQ92643
Genomic Variants (DGV)PIGK [DGVbeta]
DECIPHERPIGK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPIGK 
Mutations
ICGC Data PortalPIGK 
TCGA Data PortalPIGK 
Broad Tumor PortalPIGK
OASIS PortalPIGK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPIGK  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPIGK
Mutations and Diseases : HGMDPIGK
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPIGK
DgiDB (Drug Gene Interaction Database)PIGK
DoCM (Curated mutations)PIGK
CIViC (Clinical Interpretations of Variants in Cancer)PIGK
Cancer3DPIGK
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605087    618879   
Orphanet
DisGeNETPIGK
MedgenPIGK
Genetic Testing Registry PIGK
NextProtQ92643 [Medical]
GENETestsPIGK
Target ValidationPIGK
Huge Navigator PIGK [HugePedia]
ClinGenPIGK
Clinical trials, drugs, therapy
MyCancerGenomePIGK
Protein Interactions : CTDPIGK
Pharm GKB GenePA33296
PharosQ92643
Clinical trialPIGK
Miscellaneous
canSAR (ICR)PIGK
HarmonizomePIGK
DataMed IndexPIGK
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPIGK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:25:17 CEST 2021

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