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PIGK (phosphatidylinositol glycan anchor biosynthesis class K)

Identity

Alias_namesphosphatidylinositol glycan
Alias_symbol (synonym)hGPI8
GPI8
Other alias
HGNC (Hugo) PIGK
LocusID (NCBI) 10026
Atlas_Id 47469
Location 1p31.1  [Link to chromosome band 1p31]
Location_base_pair Starts at 77088982 and ends at 77219447 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PIGK (1p31.1) / KIF21A (12q12)PIGK (1p31.1) / SPATA6 (1p33)PIGK (1p31.1) / ST6GALNAC3 (1p31.1)
PIGK 1p31.1 / ST6GALNAC3 1p31.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PIGK   8965
Cards
Entrez_Gene (NCBI)PIGK  10026  phosphatidylinositol glycan anchor biosynthesis class K
AliasesGPI8
GeneCards (Weizmann)PIGK
Ensembl hg19 (Hinxton)ENSG00000142892 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142892 [Gene_View]  chr1:77088982-77219447 [Contig_View]  PIGK [Vega]
ICGC DataPortalENSG00000142892
TCGA cBioPortalPIGK
AceView (NCBI)PIGK
Genatlas (Paris)PIGK
WikiGenes10026
SOURCE (Princeton)PIGK
Genetics Home Reference (NIH)PIGK
Genomic and cartography
GoldenPath hg38 (UCSC)PIGK  -     chr1:77088982-77219447 -  1p31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PIGK  -     1p31.1   [Description]    (hg19-Feb_2009)
EnsemblPIGK - 1p31.1 [CytoView hg19]  PIGK - 1p31.1 [CytoView hg38]
Mapping of homologs : NCBIPIGK [Mapview hg19]  PIGK [Mapview hg38]
OMIM605087   
Gene and transcription
Genbank (Entrez)AF022913 AK055071 AK304340 AK313015 BC020737
RefSeq transcript (Entrez)NM_005482
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PIGK
Cluster EST : UnigeneHs.178305 [ NCBI ]
CGAP (NCI)Hs.178305
Alternative Splicing GalleryENSG00000142892
Gene ExpressionPIGK [ NCBI-GEO ]   PIGK [ EBI - ARRAY_EXPRESS ]   PIGK [ SEEK ]   PIGK [ MEM ]
Gene Expression Viewer (FireBrowse)PIGK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10026
GTEX Portal (Tissue expression)PIGK
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92643   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92643  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92643
Splice isoforms : SwissVarQ92643
Catalytic activity : Enzyme3.-.-.- [ Enzyme-Expasy ]   3.-.-.-3.-.-.- [ IntEnz-EBI ]   3.-.-.- [ BRENDA ]   3.-.-.- [ KEGG ]   
PhosPhoSitePlusQ92643
Domains : Interpro (EBI)GPI_transamidase    Peptidase_C13   
Domain families : Pfam (Sanger)Peptidase_C13 (PF01650)   
Domain families : Pfam (NCBI)pfam01650   
Conserved Domain (NCBI)PIGK
DMDM Disease mutations10026
Blocks (Seattle)PIGK
SuperfamilyQ92643
Human Protein AtlasENSG00000142892
Peptide AtlasQ92643
HPRD05474
IPIIPI00022543   IPI00514325   IPI00943022   IPI00478201   
Protein Interaction databases
DIP (DOE-UCLA)Q92643
IntAct (EBI)Q92643
FunCoupENSG00000142892
BioGRIDPIGK
STRING (EMBL)PIGK
ZODIACPIGK
Ontologies - Pathways
QuickGOQ92643
Ontology : AmiGOprotein disulfide isomerase activity  GPI-anchor transamidase activity  GPI-anchor transamidase activity  protein binding  endoplasmic reticulum membrane  proteolysis  cysteine-type peptidase activity  membrane  attachment of GPI anchor to protein  integral component of endoplasmic reticulum membrane  GPI anchor binding  protein localization to cell surface  GPI-anchor transamidase complex  
Ontology : EGO-EBIprotein disulfide isomerase activity  GPI-anchor transamidase activity  GPI-anchor transamidase activity  protein binding  endoplasmic reticulum membrane  proteolysis  cysteine-type peptidase activity  membrane  attachment of GPI anchor to protein  integral component of endoplasmic reticulum membrane  GPI anchor binding  protein localization to cell surface  GPI-anchor transamidase complex  
Pathways : KEGGGlycosylphosphatidylinositol(GPI)-anchor biosynthesis   
NDEx NetworkPIGK
Atlas of Cancer Signalling NetworkPIGK
Wikipedia pathwaysPIGK
Orthology - Evolution
OrthoDB10026
GeneTree (enSembl)ENSG00000142892
Phylogenetic Trees/Animal Genes : TreeFamPIGK
HOVERGENQ92643
HOGENOMQ92643
Homologs : HomoloGenePIGK
Homology/Alignments : Family Browser (UCSC)PIGK
Gene fusions - Rearrangements
Fusion : MitelmanPIGK/SPATA6 [1p31.1/1p33]  
Fusion : MitelmanPIGK/ST6GALNAC3 [1p31.1/1p31.1]  [t(1;1)(p31;p31)]  
Fusion: TCGAPIGK 1p31.1 ST6GALNAC3 1p31.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPIGK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIGK
dbVarPIGK
ClinVarPIGK
1000_GenomesPIGK 
Exome Variant ServerPIGK
ExAC (Exome Aggregation Consortium)PIGK (select the gene name)
Genetic variants : HAPMAP10026
Genomic Variants (DGV)PIGK [DGVbeta]
DECIPHERPIGK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPIGK 
Mutations
ICGC Data PortalPIGK 
TCGA Data PortalPIGK 
Broad Tumor PortalPIGK
OASIS PortalPIGK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPIGK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPIGK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PIGK
DgiDB (Drug Gene Interaction Database)PIGK
DoCM (Curated mutations)PIGK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PIGK (select a term)
intoGenPIGK
Cancer3DPIGK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605087   
Orphanet
MedgenPIGK
Genetic Testing Registry PIGK
NextProtQ92643 [Medical]
TSGene10026
GENETestsPIGK
Target ValidationPIGK
Huge Navigator PIGK [HugePedia]
snp3D : Map Gene to Disease10026
BioCentury BCIQPIGK
ClinGenPIGK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10026
Chemical/Pharm GKB GenePA33296
Clinical trialPIGK
Miscellaneous
canSAR (ICR)PIGK (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePIGK
EVEXPIGK
GoPubMedPIGK
iHOPPIGK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:24:46 CEST 2017

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