Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PIK3AP1 (phosphoinositide-3-kinase adaptor protein 1)

Identity

Alias_symbol (synonym)BCAP
FLJ35564
Other alias
HGNC (Hugo) PIK3AP1
LocusID (NCBI) 118788
Atlas_Id 54535
Location 10q24.1  [Link to chromosome band 10q24]
Location_base_pair Starts at 96593312 and ends at 96720522 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BLNK (10q24.1) / PIK3AP1 (10q24.1)CRCP (7q11.21) / PIK3AP1 (10q24.1)TM9SF3 (10q24.1) / PIK3AP1 (10q24.1)
BLNK 10q24.1 / PIK3AP1 10q24.1TM9SF3 10q24.1 / PIK3AP1 10q24.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PIK3AP1   30034
Cards
Entrez_Gene (NCBI)PIK3AP1  118788  phosphoinositide-3-kinase adaptor protein 1
AliasesBCAP
GeneCards (Weizmann)PIK3AP1
Ensembl hg19 (Hinxton)ENSG00000155629 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155629 [Gene_View]  chr10:96593312-96720522 [Contig_View]  PIK3AP1 [Vega]
ICGC DataPortalENSG00000155629
TCGA cBioPortalPIK3AP1
AceView (NCBI)PIK3AP1
Genatlas (Paris)PIK3AP1
WikiGenes118788
SOURCE (Princeton)PIK3AP1
Genetics Home Reference (NIH)PIK3AP1
Genomic and cartography
GoldenPath hg38 (UCSC)PIK3AP1  -     chr10:96593312-96720522 -  10q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PIK3AP1  -     10q24.1   [Description]    (hg19-Feb_2009)
EnsemblPIK3AP1 - 10q24.1 [CytoView hg19]  PIK3AP1 - 10q24.1 [CytoView hg38]
Mapping of homologs : NCBIPIK3AP1 [Mapview hg19]  PIK3AP1 [Mapview hg38]
OMIM607942   
Gene and transcription
Genbank (Entrez)AI826732 AK092883 AK122584 AK125635 AM393069
RefSeq transcript (Entrez)NM_152309
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PIK3AP1
Cluster EST : UnigeneHs.310456 [ NCBI ]
CGAP (NCI)Hs.310456
Alternative Splicing GalleryENSG00000155629
Gene ExpressionPIK3AP1 [ NCBI-GEO ]   PIK3AP1 [ EBI - ARRAY_EXPRESS ]   PIK3AP1 [ SEEK ]   PIK3AP1 [ MEM ]
Gene Expression Viewer (FireBrowse)PIK3AP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)118788
GTEX Portal (Tissue expression)PIK3AP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZUJ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZUJ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZUJ8
Splice isoforms : SwissVarQ6ZUJ8
PhosPhoSitePlusQ6ZUJ8
Domaine pattern : Prosite (Expaxy)DBB (PS51376)   
Domains : Interpro (EBI)Ankyrin_rpt-contain_dom    DBB_domain   
Domain families : Pfam (Sanger)DBB (PF14545)   
Domain families : Pfam (NCBI)pfam14545   
Domain families : Smart (EMBL)DBB (SM01282)  
Conserved Domain (NCBI)PIK3AP1
DMDM Disease mutations118788
Blocks (Seattle)PIK3AP1
PDB (SRS)5FOR   
PDB (PDBSum)5FOR   
PDB (IMB)5FOR   
PDB (RSDB)5FOR   
Structural Biology KnowledgeBase5FOR   
SCOP (Structural Classification of Proteins)5FOR   
CATH (Classification of proteins structures)5FOR   
SuperfamilyQ6ZUJ8
Human Protein AtlasENSG00000155629
Peptide AtlasQ6ZUJ8
HPRD06401
IPIIPI00783519   IPI00643527   IPI00180939   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZUJ8
IntAct (EBI)Q6ZUJ8
FunCoupENSG00000155629
BioGRIDPIK3AP1
STRING (EMBL)PIK3AP1
ZODIACPIK3AP1
Ontologies - Pathways
QuickGOQ6ZUJ8
Ontology : AmiGOcytosol  cytosol  plasma membrane  regulation of phosphatidylinositol 3-kinase signaling  positive regulation of phosphatidylinositol 3-kinase signaling  membrane  toll-like receptor 2 signaling pathway  toll-like receptor 4 signaling pathway  toll-like receptor 7 signaling pathway  toll-like receptor 9 signaling pathway  phosphatidylinositol 3-kinase regulatory subunit binding  identical protein binding  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  phosphatidylinositol-mediated signaling  regulation of inflammatory response  
Ontology : EGO-EBIcytosol  cytosol  plasma membrane  regulation of phosphatidylinositol 3-kinase signaling  positive regulation of phosphatidylinositol 3-kinase signaling  membrane  toll-like receptor 2 signaling pathway  toll-like receptor 4 signaling pathway  toll-like receptor 7 signaling pathway  toll-like receptor 9 signaling pathway  phosphatidylinositol 3-kinase regulatory subunit binding  identical protein binding  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  phosphatidylinositol-mediated signaling  regulation of inflammatory response  
Pathways : KEGGPI3K-Akt signaling pathway    B cell receptor signaling pathway   
NDEx NetworkPIK3AP1
Atlas of Cancer Signalling NetworkPIK3AP1
Wikipedia pathwaysPIK3AP1
Orthology - Evolution
OrthoDB118788
GeneTree (enSembl)ENSG00000155629
Phylogenetic Trees/Animal Genes : TreeFamPIK3AP1
HOVERGENQ6ZUJ8
HOGENOMQ6ZUJ8
Homologs : HomoloGenePIK3AP1
Homology/Alignments : Family Browser (UCSC)PIK3AP1
Gene fusions - Rearrangements
Fusion : MitelmanBLNK/PIK3AP1 [10q24.1/10q24.1]  [t(10;10)(q24;q24)]  
Fusion : MitelmanCRCP/PIK3AP1 [7q11.21/10q24.1]  [t(7;10)(q11;q24)]  
Fusion : MitelmanTM9SF3/PIK3AP1 [10q24.1/10q24.1]  [t(10;10)(q24;q24)]  
Fusion: TCGABLNK 10q24.1 PIK3AP1 10q24.1 BRCA
Fusion: TCGATM9SF3 10q24.1 PIK3AP1 10q24.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPIK3AP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIK3AP1
dbVarPIK3AP1
ClinVarPIK3AP1
1000_GenomesPIK3AP1 
Exome Variant ServerPIK3AP1
ExAC (Exome Aggregation Consortium)PIK3AP1 (select the gene name)
Genetic variants : HAPMAP118788
Genomic Variants (DGV)PIK3AP1 [DGVbeta]
DECIPHERPIK3AP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPIK3AP1 
Mutations
ICGC Data PortalPIK3AP1 
TCGA Data PortalPIK3AP1 
Broad Tumor PortalPIK3AP1
OASIS PortalPIK3AP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPIK3AP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPIK3AP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PIK3AP1
DgiDB (Drug Gene Interaction Database)PIK3AP1
DoCM (Curated mutations)PIK3AP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PIK3AP1 (select a term)
intoGenPIK3AP1
Cancer3DPIK3AP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607942   
Orphanet
MedgenPIK3AP1
Genetic Testing Registry PIK3AP1
NextProtQ6ZUJ8 [Medical]
TSGene118788
GENETestsPIK3AP1
Huge Navigator PIK3AP1 [HugePedia]
snp3D : Map Gene to Disease118788
BioCentury BCIQPIK3AP1
ClinGenPIK3AP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD118788
Chemical/Pharm GKB GenePA134979629
Clinical trialPIK3AP1
Miscellaneous
canSAR (ICR)PIK3AP1 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePIK3AP1
EVEXPIK3AP1
GoPubMedPIK3AP1
iHOPPIK3AP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:31:14 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.