PIK3C2G (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma)

2003-06-01  

Identity

HGNC
LOCATION
12p12.3
LOCUSID
ALIAS
PI3K-C2-gamma,PI3K-C2GAMMA
FUSION GENES

Other Information

Locus ID:

NCBI: 5288
MIM: 609001
HGNC: 8973
Ensembl: ENSG00000139144

Variants:

dbSNP: 5288
ClinVar: 5288
TCGA: ENSG00000139144
COSMIC: PIK3C2G

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139144ENST00000433979O75747
ENSG00000139144ENST00000535651F5H7Y7
ENSG00000139144ENST00000536967A0A087WV31
ENSG00000139144ENST00000538779F5H369
ENSG00000139144ENST00000546003F5GWG6

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Inositol phosphate metabolismKEGGko00562
Phosphatidylinositol signaling systemKEGGko04070
Inositol phosphate metabolismKEGGhsa00562
Phosphatidylinositol signaling systemKEGGhsa04070
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
PI MetabolismREACTOMER-HSA-1483255
Synthesis of PIPs at the Golgi membraneREACTOMER-HSA-1660514
Synthesis of PIPs at the plasma membraneREACTOMER-HSA-1660499

References

Pubmed IDYearTitleCitations
178937072008An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia.44
189961022009Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.11
179914252008Association of the PIK3C2G gene polymorphisms with type 2 DM in a Japanese population.9
179914252008Association of the PIK3C2G gene polymorphisms with type 2 DM in a Japanese population.9
249836632015Development of first lead structures for phosphoinositide 3-kinase-C2γ inhibitors.7
206026152010Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?2

Citation

Dessen P

PIK3C2G (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41713/pik3c2g