PIK3C3 (phosphoinositide-3-kinase, class 3)

Identity

Other names	MGC61518
	Vps34
HGNC	PIK3C3
Location	18q12.3
Location_base_pair	Starts at 37789197 and ends at 37915444 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PIK3C3   8974
Entrez_Gene	PIK3C3  5289  phosphoinositide-3-kinase, class 3
	Cards
GeneCards	PIK3C3
Ensembl	ENSG00000078142 [Gene_View]  PIK3C3 [Vega]
Genatlas	PIK3C3
	Genomic and cartography
GoldenPath	PIK3C3  -  18q12.3   chr18:37789197-37915444 +  18q12.3   [Description]    (hg18-March_2006)
Ensembl	PIK3C3 - 18q12.3 [CytoView]
NCBI	Mapview
OMIM	602609 Disease map [OMIM]
HomoloGene	PIK3C3
	Gene and transcription
Genbank	AK022653 [ ENTREZ ]
Genbank	AK090567 [ ENTREZ ]
Genbank	AK298517 [ ENTREZ ]
Genbank	AK308364 [ ENTREZ ]
Genbank	BC010388 [ ENTREZ ]
RefSeq	NM_002647 [ SRS ]    NM_002647 [ ENTREZ ]
RefSeq	AC_000061 [ SRS ]    AC_000061 [ ENTREZ ]
RefSeq	AC_000150 [ SRS ]    AC_000150 [ ENTREZ ]
RefSeq	NC_000018 [ SRS ]    NC_000018 [ ENTREZ ]
RefSeq	NT_010966 [ SRS ]    NT_010966 [ ENTREZ ]
RefSeq	NW_001838467 [ SRS ]    NW_001838467 [ ENTREZ ]
RefSeq	NW_927095 [ SRS ]    NW_927095 [ ENTREZ ]
CCDS	PIK3C3 CCDS - NCBI
AceView	PIK3C3 AceView - NCBI
Unigene	Hs.464971 [ SRS ]    Hs.464971 [ NCBI ]
Fast-db	3903 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q8NEB9 [ SRS]    Q8NEB9 [ EXPASY ]     Q8NEB9 [ INTERPRO ]     Q8NEB9 [ UNIPROT ] Q8NEB9 [ VarSplice FASTA ]
Prosite	PS00915 PI3_4_KINASE_1 [ SRS ]    PS00915 PI3_4_KINASE_1 [ Expasy ]
Prosite	PS00916 PI3_4_KINASE_2 [ SRS ]    PS00916 PI3_4_KINASE_2 [ Expasy ]
Prosite	PS50290 PI3_4_KINASE_3 [ SRS ]    PS50290 PI3_4_KINASE_3 [ Expasy ]
Interpro	IPR000008 C2_Ca-dep [ SRS ]    IPR000008 C2_Ca-dep [ EBI ]
Interpro	IPR000403 PI3/4_kinase_cat [ SRS ]    IPR000403 PI3/4_kinase_cat [ EBI ]
Interpro	IPR002420 PI3K_C2 [ SRS ]    IPR002420 PI3K_C2 [ EBI ]
Interpro	IPR008290 PI3K_Vps34 [ SRS ]    IPR008290 PI3K_Vps34 [ EBI ]
Interpro	IPR001263 PI3Ka [ SRS ]    IPR001263 PI3Ka [ EBI ]
Interpro	IPR015433 PI_Kinase [ SRS ]    IPR015433 PI_Kinase [ EBI ]
CluSTr	Q8NEB9
Pfam	PF00454 PI3_PI4_kinase [ SRS ]    PF00454 PI3_PI4_kinase [ Sanger ]    pfam00454 [ NCBI-CDD ]
Pfam	PF00792 PI3K_C2 [ SRS ]    PF00792 PI3K_C2 [ Sanger ]    pfam00792 [ NCBI-CDD ]
Pfam	PF00613 PI3Ka [ SRS ]    PF00613 PI3Ka [ Sanger ]    pfam00613 [ NCBI-CDD ]
Smart	SM00239 C2 [EMBL]
Smart	SM00142 PI3K_C2 [EMBL]
Smart	SM00145 PI3Ka [EMBL]
Smart	SM00146 PI3Kc [EMBL]
Blocks	Q8NEB9
HPRD	04009
	Protein Interaction databases
DIP	Q8NEB9
IntAct	Q8NEB9
	Polymorphism : SNP, mutations, diseases
OMIM	602609    [ map ]
GENETests	602609
SNP	PIK3C3 [dbSNP-NCBI]
SNP	NM_002647 [SNP-NCI]
SNP	PIK3C3 [GeneSNPs - Utah]  PIK3C3] [HGBASE - SRS]
HAPMAP	PIK3C3 [HAPMAP]
COSMIC	PIK3C3 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PIK3C3
Genetic Association	PIK3C3
CDC HuGE	PIK3C3
	General knowledge
Family Browser	PIK3C3 [UCSC Family Browser]
SOURCE	NM_002647
SMD	Hs.464971
SAGE	Hs.464971
Enzyme	2.7.1.137 [ Enzyme-Expasy ]   2.7.1.137 [ Enzyme-SRS ]   2.7.1.137 [ IntEnz-EBI ]   2.7.1.137 [ BRENDA ]   2.7.1.137 [ KEGG ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	inositol or phosphatidylinositol kinase activity [Amigo]  inositol or phosphatidylinositol kinase activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	cytosol [Amigo]  cytosol
GO	phosphoinositide 3-kinase complex [Amigo]  phosphoinositide 3-kinase complex
GO	1-phosphatidylinositol-3-kinase activity [Amigo]  1-phosphatidylinositol-3-kinase activity
GO	transferase activity [Amigo]  transferase activity
GO	phosphotransferase activity, alcohol group as acceptor [Amigo]  phosphotransferase activity, alcohol group as acceptor
GO	manganese ion binding [Amigo]  manganese ion binding
GO	phosphoinositide phosphorylation [Amigo]  phosphoinositide phosphorylation
GO	phosphoinositide-mediated signaling [Amigo]  phosphoinositide-mediated signaling
KEGG	Inositol phosphate metabolism
KEGG	Phosphatidylinositol signaling system
KEGG	Regulation of autophagy
PubGene	PIK3C3
TreeFam	PIK3C3
CTD	5289 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PIK3C3 Related clones (RZPD - Berlin)
	PubMed
PubMed	37 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:03:34 2008