PIK3CD (phosphoinositide-3-kinase, catalytic, delta polypeptide)

Identity

Other names	p110D
HGNC	PIK3CD
Location	1p36.2
Location_base_pair	Starts at 9634377 and ends at 9711759 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PIK3CD   8977
Entrez_Gene	PIK3CD  5293  phosphoinositide-3-kinase, catalytic, delta polypeptide
	Cards
GeneCards	PIK3CD
Ensembl	ENSG00000171608 [Gene_View]  PIK3CD [Vega]
Genatlas	PIK3CD
	Genomic and cartography
GoldenPath	PIK3CD  -  1p36.2   chr1:9634377-9711759 +  1p36.22   [Description]    (hg18-March_2006)
Ensembl	PIK3CD - 1p36.22 [CytoView]
NCBI	Mapview
OMIM	602839 Disease map [OMIM]
HomoloGene	PIK3CD
	Gene and transcription
Genbank	AB208835 [ ENTREZ ]
Genbank	AK314191 [ ENTREZ ]
Genbank	BC030263 [ ENTREZ ]
Genbank	BC132919 [ ENTREZ ]
Genbank	BC132921 [ ENTREZ ]
RefSeq	NM_005026 [ SRS ]    NM_005026 [ ENTREZ ]
RefSeq	AC_000044 [ SRS ]    AC_000044 [ ENTREZ ]
RefSeq	AC_000133 [ SRS ]    AC_000133 [ ENTREZ ]
RefSeq	NC_000001 [ SRS ]    NC_000001 [ ENTREZ ]
RefSeq	NT_021937 [ SRS ]    NT_021937 [ ENTREZ ]
RefSeq	NW_001838523 [ SRS ]    NW_001838523 [ ENTREZ ]
RefSeq	NW_923572 [ SRS ]    NW_923572 [ ENTREZ ]
CCDS	PIK3CD CCDS - NCBI
AceView	PIK3CD AceView - NCBI
Unigene	Hs.518451 [ SRS ]    Hs.518451 [ NCBI ]
Fast-db	3946 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O00329 [ SRS]    O00329 [ EXPASY ]     O00329 [ INTERPRO ]     O00329 [ UNIPROT ] O00329 [ VarSplice FASTA ]
Prosite	PS00915 PI3_4_KINASE_1 [ SRS ]    PS00915 PI3_4_KINASE_1 [ Expasy ]
Prosite	PS00916 PI3_4_KINASE_2 [ SRS ]    PS00916 PI3_4_KINASE_2 [ Expasy ]
Prosite	PS50290 PI3_4_KINASE_3 [ SRS ]    PS50290 PI3_4_KINASE_3 [ Expasy ]
Interpro	IPR000403 PI3/4_kinase_cat [ SRS ]    IPR000403 PI3/4_kinase_cat [ EBI ]
Interpro	IPR002420 PI3K_C2 [ SRS ]    IPR002420 PI3K_C2 [ EBI ]
Interpro	IPR003113 PI3K_p85_bd [ SRS ]    IPR003113 PI3K_p85_bd [ EBI ]
Interpro	IPR000341 PI3K_ras_bd [ SRS ]    IPR000341 PI3K_ras_bd [ EBI ]
Interpro	IPR001263 PI3Ka [ SRS ]    IPR001263 PI3Ka [ EBI ]
Interpro	IPR015433 PI_Kinase [ SRS ]    IPR015433 PI_Kinase [ EBI ]
CluSTr	O00329
Pfam	PF00454 PI3_PI4_kinase [ SRS ]    PF00454 PI3_PI4_kinase [ Sanger ]    pfam00454 [ NCBI-CDD ]
Pfam	PF00792 PI3K_C2 [ SRS ]    PF00792 PI3K_C2 [ Sanger ]    pfam00792 [ NCBI-CDD ]
Pfam	PF02192 PI3K_p85B [ SRS ]    PF02192 PI3K_p85B [ Sanger ]    pfam02192 [ NCBI-CDD ]
Pfam	PF00794 PI3K_rbd [ SRS ]    PF00794 PI3K_rbd [ Sanger ]    pfam00794 [ NCBI-CDD ]
Pfam	PF00613 PI3Ka [ SRS ]    PF00613 PI3Ka [ Sanger ]    pfam00613 [ NCBI-CDD ]
Smart	SM00142 PI3K_C2 [EMBL]
Smart	SM00143 PI3K_p85B [EMBL]
Smart	SM00144 PI3K_rbd [EMBL]
Smart	SM00145 PI3Ka [EMBL]
Smart	SM00146 PI3Kc [EMBL]
Blocks	O00329
	Protein Interaction databases
DIP	O00329
IntAct	O00329
	Polymorphism : SNP, mutations, diseases
OMIM	602839    [ map ]
GENETests	602839
SNP	PIK3CD [dbSNP-NCBI]
SNP	NM_005026 [SNP-NCI]
SNP	PIK3CD [GeneSNPs - Utah]  PIK3CD] [HGBASE - SRS]
HAPMAP	PIK3CD [HAPMAP]
COSMIC	PIK3CD [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PIK3CD
Genetic Association	PIK3CD
CDC HuGE	PIK3CD
	General knowledge
Family Browser	PIK3CD [UCSC Family Browser]
SOURCE	NM_005026
SMD	Hs.518451
SAGE	Hs.518451
Enzyme	2.7.1.153 [ Enzyme-Expasy ]   2.7.1.153 [ Enzyme-SRS ]   2.7.1.153 [ IntEnz-EBI ]   2.7.1.153 [ BRENDA ]   2.7.1.153 [ KEGG ]
GO	inositol or phosphatidylinositol kinase activity [Amigo]  inositol or phosphatidylinositol kinase activity
GO	binding [Amigo]  binding
GO	phosphoinositide 3-kinase complex [Amigo]  phosphoinositide 3-kinase complex
GO	phosphoinositide 3-kinase complex [Amigo]  phosphoinositide 3-kinase complex
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	signal transduction [Amigo]  signal transduction
GO	signal transduction [Amigo]  signal transduction
GO	1-phosphatidylinositol-3-kinase activity [Amigo]  1-phosphatidylinositol-3-kinase activity
GO	1-phosphatidylinositol-3-kinase activity [Amigo]  1-phosphatidylinositol-3-kinase activity
GO	transferase activity [Amigo]  transferase activity
GO	phosphotransferase activity, alcohol group as acceptor [Amigo]  phosphotransferase activity, alcohol group as acceptor
GO	phosphoinositide phosphorylation [Amigo]  phosphoinositide phosphorylation
GO	phosphatidylinositol-4,5-bisphosphate 3-kinase activity [Amigo]  phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO	phosphoinositide-mediated signaling [Amigo]  phosphoinositide-mediated signaling
KEGG	Inositol phosphate metabolism
KEGG	Phosphatidylinositol signaling system
KEGG	mTOR signaling pathway
KEGG	Apoptosis
KEGG	VEGF signaling pathway
KEGG	Focal adhesion
KEGG	Toll-like receptor signaling pathway
KEGG	Jak-STAT signaling pathway
KEGG	Natural killer cell mediated cytotoxicity
KEGG	T cell receptor signaling pathway
KEGG	B cell receptor signaling pathway
KEGG	Fc epsilon RI signaling pathway
KEGG	Leukocyte transendothelial migration
KEGG	Regulation of actin cytoskeleton
KEGG	Insulin signaling pathway
KEGG	Type II diabetes mellitus
KEGG	Colorectal cancer
PubGene	PIK3CD
TreeFam	PIK3CD
CTD	5293 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PIK3CD Related clones (RZPD - Berlin)
	PubMed
PubMed	36 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:03:35 2008