PIK3IP1 (phosphoinositide-3-kinase interacting protein 1)

2008-09-01  

Identity

HGNC
PIK3IP1
LOCATION
22q12.2
LOCUSID
113791
ALIAS
HGFL,TrIP,hHGFL(S)
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 113791
HGNC: 24942
Ensembl: ENSG00000100100

Variants:

dbSNP: 113791
ClinVar: 113791
TCGA: ENSG00000100100
COSMIC: PIK3IP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100100ENST00000215912Q96FE7
ENSG00000100100ENST00000215912A0A024R1M3
ENSG00000100100ENST00000402249Q96FE7
ENSG00000100100ENST00000441972Q96FE7
ENSG00000100100ENST00000443175C9JMK5

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
186326112008PIK3IP1, a negative regulator of PI3K, suppresses the development of hepatocellular carcinoma.37
174752142007PI3K is negatively regulated by PIK3IP1, a novel p110 interacting protein.27
227069932012Inhibition of T-cell activation by PIK3IP1.10
285491022017Long non-coding RNA CCAT1/miR-148a axis promotes osteosarcoma proliferation and migration through regulating PIK3IP1.10
190888252008[Both PIK3IP1 and its novel found splicing isoform, PIK3IP1-v1, are located on cell membrane and induce cell apoptosis].1

Citation

Dessen P

PIK3IP1 (phosphoinositide-3-kinase interacting protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-09-01

Online version: http://atlasgeneticsoncology.org/gene/50366/pik3ip1