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PIK3R6 (phosphoinositide-3-kinase, regulatory subunit 6)

Identity

Alias_namesC17orf38
chromosome 17 open reading frame 38
phosphoinositide-3-kinase, regulatory subunit 6
Alias_symbol (synonym)FLJ34500
HsT41028
p87PIKAP
Other aliasp84 PIKAP
p87(PIKAP)
HGNC (Hugo) PIK3R6
LocusID (NCBI) 146850
Atlas_Id 71919
Location 17p13.1  [Link to chromosome band 17p13]
Location_base_pair Starts at 8706041 and ends at 8770994 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PIK3R6   27101
Cards
Entrez_Gene (NCBI)PIK3R6  146850  phosphoinositide-3-kinase, regulatory subunit 6
AliasesC17orf38; HsT41028; p84; p87(PIKAP); 
p87PIKAP
GeneCards (Weizmann)PIK3R6
Ensembl hg19 (Hinxton)ENSG00000276231 [Gene_View]  chr17:8706041-8770994 [Contig_View]  PIK3R6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000276231 [Gene_View]  chr17:8706041-8770994 [Contig_View]  PIK3R6 [Vega]
ICGC DataPortalENSG00000276231
TCGA cBioPortalPIK3R6
AceView (NCBI)PIK3R6
Genatlas (Paris)PIK3R6
WikiGenes146850
SOURCE (Princeton)PIK3R6
Genetics Home Reference (NIH)PIK3R6
Genomic and cartography
GoldenPath hg19 (UCSC)PIK3R6  -     chr17:8706041-8770994 -  17p13.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PIK3R6  -     17p13.1   [Description]    (hg38-Dec_2013)
EnsemblPIK3R6 - 17p13.1 [CytoView hg19]  PIK3R6 - 17p13.1 [CytoView hg38]
Mapping of homologs : NCBIPIK3R6 [Mapview hg19]  PIK3R6 [Mapview hg38]
OMIM611462   
Gene and transcription
Genbank (Entrez)AK091819 AL833037 AY753192 BC110301 BC125169
RefSeq transcript (Entrez)NM_001010855 NM_001290211
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_033091 NT_010718 NW_004929405
Consensus coding sequences : CCDS (NCBI)PIK3R6
Cluster EST : UnigeneHs.255809 [ NCBI ]
CGAP (NCI)Hs.255809
Alternative Splicing GalleryENSG00000276231
Gene ExpressionPIK3R6 [ NCBI-GEO ]   PIK3R6 [ EBI - ARRAY_EXPRESS ]   PIK3R6 [ SEEK ]   PIK3R6 [ MEM ]
Gene Expression Viewer (FireBrowse)PIK3R6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)146850
GTEX Portal (Tissue expression)PIK3R6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5UE93   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5UE93  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5UE93
Splice isoforms : SwissVarQ5UE93
PhosPhoSitePlusQ5UE93
Domains : Interpro (EBI)PIK3R5/6   
Domain families : Pfam (Sanger)PI3K_1B_p101 (PF10486)   
Domain families : Pfam (NCBI)pfam10486   
Conserved Domain (NCBI)PIK3R6
DMDM Disease mutations146850
Blocks (Seattle)PIK3R6
SuperfamilyQ5UE93
Human Protein AtlasENSG00000276231
Peptide AtlasQ5UE93
HPRD12682
IPIIPI00088953   
Protein Interaction databases
DIP (DOE-UCLA)Q5UE93
IntAct (EBI)Q5UE93
FunCoupENSG00000276231
BioGRIDPIK3R6
STRING (EMBL)PIK3R6
ZODIACPIK3R6
Ontologies - Pathways
QuickGOQ5UE93
Ontology : AmiGOangiogenesis  protein binding  cytosol  phosphatidylinositol 3-kinase complex, class IB  phospholipid metabolic process  phosphatidylinositol biosynthetic process  G-protein coupled receptor signaling pathway  blood coagulation  membrane  platelet activation  regulation of natural killer cell mediated cytotoxicity  positive regulation of MAP kinase activity  regulation of phosphatidylinositol 3-kinase activity  regulation of phosphatidylinositol 3-kinase activity  small molecule metabolic process  positive regulation of angiogenesis  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  1-phosphatidylinositol-3-kinase regulator activity  
Ontology : EGO-EBIangiogenesis  protein binding  cytosol  phosphatidylinositol 3-kinase complex, class IB  phospholipid metabolic process  phosphatidylinositol biosynthetic process  G-protein coupled receptor signaling pathway  blood coagulation  membrane  platelet activation  regulation of natural killer cell mediated cytotoxicity  positive regulation of MAP kinase activity  regulation of phosphatidylinositol 3-kinase activity  regulation of phosphatidylinositol 3-kinase activity  small molecule metabolic process  positive regulation of angiogenesis  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  1-phosphatidylinositol-3-kinase regulator activity  
NDEx NetworkPIK3R6
Atlas of Cancer Signalling NetworkPIK3R6
Wikipedia pathwaysPIK3R6
Orthology - Evolution
OrthoDB146850
GeneTree (enSembl)ENSG00000276231
Phylogenetic Trees/Animal Genes : TreeFamPIK3R6
HOVERGENQ5UE93
HOGENOMQ5UE93
Homologs : HomoloGenePIK3R6
Homology/Alignments : Family Browser (UCSC)PIK3R6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPIK3R6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIK3R6
dbVarPIK3R6
ClinVarPIK3R6
1000_GenomesPIK3R6 
Exome Variant ServerPIK3R6
ExAC (Exome Aggregation Consortium)PIK3R6 (select the gene name)
Genetic variants : HAPMAP146850
Genomic Variants (DGV)PIK3R6 [DGVbeta]
DECIPHER (Syndromes)17:8706041-8770994  ENSG00000276231
CONAN: Copy Number AnalysisPIK3R6 
Mutations
ICGC Data PortalPIK3R6 
TCGA Data PortalPIK3R6 
Broad Tumor PortalPIK3R6
OASIS PortalPIK3R6 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPIK3R6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PIK3R6
DgiDB (Drug Gene Interaction Database)PIK3R6
DoCM (Curated mutations)PIK3R6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PIK3R6 (select a term)
intoGenPIK3R6
Cancer3DPIK3R6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611462   
Orphanet
MedgenPIK3R6
Genetic Testing Registry PIK3R6
NextProtQ5UE93 [Medical]
TSGene146850
GENETestsPIK3R6
Huge Navigator PIK3R6 [HugePedia]
snp3D : Map Gene to Disease146850
BioCentury BCIQPIK3R6
ClinGenPIK3R6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD146850
Chemical/Pharm GKB GenePA162399570
Clinical trialPIK3R6
Miscellaneous
canSAR (ICR)PIK3R6 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePIK3R6
EVEXPIK3R6
GoPubMedPIK3R6
iHOPPIK3R6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:38:40 CET 2017

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