Identity
HGNC
LOCATION
2q34
LOCUSID
ALIAS
CFD,FAB1,HEL37,PIP5K,PIP5K3,ZFYVE29
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 200576
MIM: 609414
HGNC: 23785
Ensembl: ENSG00000115020
Variants:
dbSNP: 200576
ClinVar: 200576
TCGA: ENSG00000115020
COSMIC: PIKFYVE
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38536415 | 2024 | Stress-induced microautophagy is coordinated with lysosome biogenesis and regulated by PIKfyve. | 0 |
| 38725096 | 2024 | Coxiella burnetii effector CvpE maintains biogenesis of Coxiella-containing vacuoles by suppressing lysosome tubulation through binding PI(3)P and perturbing PIKfyve activity on lysosomes. | 0 |
| 38743625 | 2024 | Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase. | 0 |
| 38942798 | 2024 | PIKfyve, expressed by CD11c-positive cells, controls tumor immunity. | 0 |
| 38536415 | 2024 | Stress-induced microautophagy is coordinated with lysosome biogenesis and regulated by PIKfyve. | 0 |
| 38725096 | 2024 | Coxiella burnetii effector CvpE maintains biogenesis of Coxiella-containing vacuoles by suppressing lysosome tubulation through binding PI(3)P and perturbing PIKfyve activity on lysosomes. | 0 |
| 38743625 | 2024 | Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase. | 0 |
| 38942798 | 2024 | PIKfyve, expressed by CD11c-positive cells, controls tumor immunity. | 0 |
| 37453227 | 2023 | PI4KA and PIKfyve: Essential phosphoinositide signaling enzymes involved in myriad human diseases. | 4 |
| 37453227 | 2023 | PI4KA and PIKfyve: Essential phosphoinositide signaling enzymes involved in myriad human diseases. | 4 |
| 35023829 | 2022 | Disruption of PIKFYVE causes congenital cataract in human and zebrafish. | 11 |
| 35708031 | 2022 | PIKfyve-Dependent Phosphoinositide Dynamics in Megakaryocyte/Platelet Granule Integrity and Platelet Functions. | 3 |
| 35023829 | 2022 | Disruption of PIKFYVE causes congenital cataract in human and zebrafish. | 11 |
| 35708031 | 2022 | PIKfyve-Dependent Phosphoinositide Dynamics in Megakaryocyte/Platelet Granule Integrity and Platelet Functions. | 3 |
| 33467550 | 2021 | Transcriptional Regulation of PIK3CD and PIKFYVE in T-Cell Acute Lymphoblastic Leukemia by IKAROS and Protein Kinase CK2. | 5 |
Citation
Dessen P
PIKFYVE (phosphoinositide kinase, FYVE-type zinc finger containing)
Atlas Genet Cytogenet Oncol Haematol. 2009-05-01
Online version: http://atlasgeneticsoncology.org/gene/50888/pikfyve
