Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11040
MIM: 300295
HGNC: 8987
Ensembl: ENSG00000102096
Variants:
dbSNP: 11040
ClinVar: 11040
TCGA: ENSG00000102096
COSMIC: PIM2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000102096 | ENST00000376509 | Q9P1W9 |
| ENSG00000102096 | ENST00000376509 | A0A024QYW7 |
| ENSG00000102096 | ENST00000442430 | C9J8V9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Acute myeloid leukemia | KEGG | ko05221 |
| Acute myeloid leukemia | KEGG | hsa05221 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37059967 | 2023 | PIM2 Promotes the Development of Ovarian Endometriosis by Enhancing Glycolysis and Fibrosis. | 1 |
| 37059967 | 2023 | PIM2 Promotes the Development of Ovarian Endometriosis by Enhancing Glycolysis and Fibrosis. | 1 |
| 35108359 | 2022 | PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma. | 4 |
| 36109523 | 2022 | Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis. | 10 |
| 35108359 | 2022 | PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma. | 4 |
| 36109523 | 2022 | Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis. | 10 |
| 33931981 | 2021 | Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer. | 20 |
| 34511042 | 2021 | Long non-coding RNA SOX21-AS1 modulates lung cancer progress upon microRNA miR-24-3p/PIM2 axis. | 16 |
| 33931981 | 2021 | Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer. | 20 |
| 34511042 | 2021 | Long non-coding RNA SOX21-AS1 modulates lung cancer progress upon microRNA miR-24-3p/PIM2 axis. | 16 |
| 31894300 | 2020 | Inhibition of PIM2 in liver cancer decreases tumor cell proliferation in vitro and in vivo primarily through the modulation of cell cycle progression. | 12 |
| 32641749 | 2020 | PIM2 promotes hepatocellular carcinoma tumorigenesis and progression through activating NF-κB signaling pathway. | 12 |
| 32754266 | 2020 | Fructose-1, 6-bisphosphatase 1 interacts with NF-κB p65 to regulate breast tumorigenesis via PIM2 induced phosphorylation. | 10 |
| 31894300 | 2020 | Inhibition of PIM2 in liver cancer decreases tumor cell proliferation in vitro and in vivo primarily through the modulation of cell cycle progression. | 12 |
| 32641749 | 2020 | PIM2 promotes hepatocellular carcinoma tumorigenesis and progression through activating NF-κB signaling pathway. | 12 |
Citation
Dessen P
PIM2 (Pim-2 proto-oncogene, serine/threonine kinase)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41718/pim2
