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PIN4 (peptidylprolyl cis/trans isomerase, NIMA-interacting 4)

Identity

Alias_namesprotein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
peptidylprolyl cis/trans isomerase NIMA-interacting, 4
Alias_symbol (synonym)PAR14
PAR17
EPVH
Other alias
HGNC (Hugo) PIN4
LocusID (NCBI) 5303
Atlas_Id 71922
Location Xq13.1  [Link to chromosome band Xq13]
Location_base_pair Starts at 72181676 and ends at 72263964 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PIN4 (Xq13.1) / ABCF2 (7q36.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PIN4   8992
Cards
Entrez_Gene (NCBI)PIN4  5303  peptidylprolyl cis/trans isomerase, NIMA-interacting 4
AliasesEPVH; PAR14; PAR17
GeneCards (Weizmann)PIN4
Ensembl hg19 (Hinxton)ENSG00000102309 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102309 [Gene_View]  chrX:72181676-72263964 [Contig_View]  PIN4 [Vega]
ICGC DataPortalENSG00000102309
TCGA cBioPortalPIN4
AceView (NCBI)PIN4
Genatlas (Paris)PIN4
WikiGenes5303
SOURCE (Princeton)PIN4
Genetics Home Reference (NIH)PIN4
Genomic and cartography
GoldenPath hg38 (UCSC)PIN4  -     chrX:72181676-72263964 +  Xq13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PIN4  -     Xq13.1   [Description]    (hg19-Feb_2009)
EnsemblPIN4 - Xq13.1 [CytoView hg19]  PIN4 - Xq13.1 [CytoView hg38]
Mapping of homologs : NCBIPIN4 [Mapview hg19]  PIN4 [Mapview hg38]
OMIM300252   
Gene and transcription
Genbank (Entrez)AB009690 AF143096 AK127605 AU098526 AV709926
RefSeq transcript (Entrez)NM_001170747 NM_006223
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PIN4
Cluster EST : UnigeneHs.655623 [ NCBI ]
CGAP (NCI)Hs.655623
Alternative Splicing GalleryENSG00000102309
Gene ExpressionPIN4 [ NCBI-GEO ]   PIN4 [ EBI - ARRAY_EXPRESS ]   PIN4 [ SEEK ]   PIN4 [ MEM ]
Gene Expression Viewer (FireBrowse)PIN4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5303
GTEX Portal (Tissue expression)PIN4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y237   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y237  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y237
Splice isoforms : SwissVarQ9Y237
Catalytic activity : Enzyme5.2.1.8 [ Enzyme-Expasy ]   5.2.1.85.2.1.8 [ IntEnz-EBI ]   5.2.1.8 [ BRENDA ]   5.2.1.8 [ KEGG ]   
PhosPhoSitePlusQ9Y237
Domaine pattern : Prosite (Expaxy)PPIC_PPIASE_2 (PS50198)   
Domains : Interpro (EBI)PPIase_PpiC   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PIN4
DMDM Disease mutations5303
Blocks (Seattle)PIN4
PDB (SRS)1EQ3    1FJD    3UI4    3UI5    3UI6   
PDB (PDBSum)1EQ3    1FJD    3UI4    3UI5    3UI6   
PDB (IMB)1EQ3    1FJD    3UI4    3UI5    3UI6   
PDB (RSDB)1EQ3    1FJD    3UI4    3UI5    3UI6   
Structural Biology KnowledgeBase1EQ3    1FJD    3UI4    3UI5    3UI6   
SCOP (Structural Classification of Proteins)1EQ3    1FJD    3UI4    3UI5    3UI6   
CATH (Classification of proteins structures)1EQ3    1FJD    3UI4    3UI5    3UI6   
SuperfamilyQ9Y237
Human Protein AtlasENSG00000102309
Peptide AtlasQ9Y237
HPRD02219
IPIIPI00941201   IPI00006658   IPI00902638   IPI00553165   IPI00552350   IPI00965103   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y237
IntAct (EBI)Q9Y237
FunCoupENSG00000102309
BioGRIDPIN4
STRING (EMBL)PIN4
ZODIACPIN4
Ontologies - Pathways
QuickGOQ9Y237
Ontology : AmiGOprotein peptidyl-prolyl isomerization  DNA binding  RNA binding  peptidyl-prolyl cis-trans isomerase activity  protein binding  nucleus  nucleolus  mitochondrial matrix  spindle  extracellular exosome  
Ontology : EGO-EBIprotein peptidyl-prolyl isomerization  DNA binding  RNA binding  peptidyl-prolyl cis-trans isomerase activity  protein binding  nucleus  nucleolus  mitochondrial matrix  spindle  extracellular exosome  
NDEx NetworkPIN4
Atlas of Cancer Signalling NetworkPIN4
Wikipedia pathwaysPIN4
Orthology - Evolution
OrthoDB5303
GeneTree (enSembl)ENSG00000102309
Phylogenetic Trees/Animal Genes : TreeFamPIN4
HOVERGENQ9Y237
HOGENOMQ9Y237
Homologs : HomoloGenePIN4
Homology/Alignments : Family Browser (UCSC)PIN4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPIN4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIN4
dbVarPIN4
ClinVarPIN4
1000_GenomesPIN4 
Exome Variant ServerPIN4
ExAC (Exome Aggregation Consortium)PIN4 (select the gene name)
Genetic variants : HAPMAP5303
Genomic Variants (DGV)PIN4 [DGVbeta]
DECIPHERPIN4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPIN4 
Mutations
ICGC Data PortalPIN4 
TCGA Data PortalPIN4 
Broad Tumor PortalPIN4
OASIS PortalPIN4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPIN4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPIN4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch PIN4
DgiDB (Drug Gene Interaction Database)PIN4
DoCM (Curated mutations)PIN4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PIN4 (select a term)
intoGenPIN4
Cancer3DPIN4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300252   
Orphanet
MedgenPIN4
Genetic Testing Registry PIN4
NextProtQ9Y237 [Medical]
TSGene5303
GENETestsPIN4
Target ValidationPIN4
Huge Navigator PIN4 [HugePedia]
snp3D : Map Gene to Disease5303
BioCentury BCIQPIN4
ClinGenPIN4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5303
Chemical/Pharm GKB GenePA33324
Clinical trialPIN4
Miscellaneous
canSAR (ICR)PIN4 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePIN4
EVEXPIN4
GoPubMedPIN4
iHOPPIN4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:34:34 CEST 2017

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