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PIP (prolactin induced protein)

Identity

Alias (NCBI)GCDFP-15
GCDFP15
GPIP4
HGNC (Hugo) PIP
HGNC Alias symbGCDFP-15
GCDFP15
GPIP4
HGNC Alias nameprolactin-inducible protein
HGNC Previous nameprolactin-induced protein
LocusID (NCBI) 5304
Atlas_Id 45702
Location 7q34  [Link to chromosome band 7q34]
Location_base_pair Starts at 143132077 and ends at 143139739 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ALDH7A1 (5q23.2) / PIP (7q34)ALDH7A1 5q23.2 / PIP 7q34

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PIP   8993
Cards
Entrez_Gene (NCBI)PIP    prolactin induced protein
AliasesGCDFP-15; GCDFP15; GPIP4
GeneCards (Weizmann)PIP
Ensembl hg19 (Hinxton)ENSG00000159763 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159763 [Gene_View]  ENSG00000159763 [Sequence]  chr7:143132077-143139739 [Contig_View]  PIP [Vega]
ICGC DataPortalENSG00000159763
TCGA cBioPortalPIP
AceView (NCBI)PIP
Genatlas (Paris)PIP
SOURCE (Princeton)PIP
Genetics Home Reference (NIH)PIP
Genomic and cartography
GoldenPath hg38 (UCSC)PIP  -     chr7:143132077-143139739 +  7q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PIP  -     7q34   [Description]    (hg19-Feb_2009)
GoldenPathPIP - 7q34 [CytoView hg19]  PIP - 7q34 [CytoView hg38]
ImmunoBaseENSG00000159763
Genome Data Viewer NCBIPIP [Mapview hg19]  
OMIM176720   
Gene and transcription
Genbank (Entrez)AK312227 BC010950 BC010951 CD723133 J03460
RefSeq transcript (Entrez)NM_002652
Consensus coding sequences : CCDS (NCBI)PIP
Gene ExpressionPIP [ NCBI-GEO ]   PIP [ EBI - ARRAY_EXPRESS ]   PIP [ SEEK ]   PIP [ MEM ]
Gene Expression Viewer (FireBrowse)PIP [ Firebrowse - Broad ]
GenevisibleExpression of PIP in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5304
GTEX Portal (Tissue expression)PIP
Human Protein AtlasENSG00000159763-PIP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP12273   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP12273  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP12273
PhosPhoSitePlusP12273
Domains : Interpro (EBI)Ig-like_fold    Ig_E-set    PIP   
Domain families : Pfam (Sanger)SVA (PF05326)   
Domain families : Pfam (NCBI)pfam05326   
Conserved Domain (NCBI)PIP
PDB (RSDB)3ES6   
PDB Europe3ES6   
PDB (PDBSum)3ES6   
PDB (IMB)3ES6   
Structural Biology KnowledgeBase3ES6   
SCOP (Structural Classification of Proteins)3ES6   
CATH (Classification of proteins structures)3ES6   
SuperfamilyP12273
AlphaFold pdb e-kbP12273   
Human Protein Atlas [tissue]ENSG00000159763-PIP [tissue]
HPRD07179
Protein Interaction databases
DIP (DOE-UCLA)P12273
IntAct (EBI)P12273
BioGRIDPIP
STRING (EMBL)PIP
ZODIACPIP
Ontologies - Pathways
QuickGOP12273
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of bitter taste  retina homeostasis  regulation of immune system process  actin binding  aspartic-type endopeptidase activity  aspartic-type endopeptidase activity  protein binding  extracellular region  extracellular space  extracellular space  extracellular space  nucleus  nucleus  proteolysis  proteolysis  positive regulation of gene expression  IgG binding  identical protein binding  transmembrane transport  extracellular exosome  negative regulation of T cell apoptotic process  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of bitter taste  retina homeostasis  regulation of immune system process  actin binding  aspartic-type endopeptidase activity  aspartic-type endopeptidase activity  protein binding  extracellular region  extracellular space  extracellular space  extracellular space  nucleus  nucleus  proteolysis  proteolysis  positive regulation of gene expression  IgG binding  identical protein binding  transmembrane transport  extracellular exosome  negative regulation of T cell apoptotic process  
NDEx NetworkPIP
Atlas of Cancer Signalling NetworkPIP
Wikipedia pathwaysPIP
Orthology - Evolution
OrthoDB5304
GeneTree (enSembl)ENSG00000159763
Phylogenetic Trees/Animal Genes : TreeFamPIP
Homologs : HomoloGenePIP
Homology/Alignments : Family Browser (UCSC)PIP
Gene fusions - Rearrangements
Fusion : MitelmanALDH7A1/PIP [5q23.2/7q34]  
Fusion : QuiverPIP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPIP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIP
dbVarPIP
ClinVarPIP
MonarchPIP
1000_GenomesPIP 
Exome Variant ServerPIP
GNOMAD BrowserENSG00000159763
Varsome BrowserPIP
ACMGPIP variants
VarityP12273
Genomic Variants (DGV)PIP [DGVbeta]
DECIPHERPIP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPIP 
Mutations
ICGC Data PortalPIP 
TCGA Data PortalPIP 
Broad Tumor PortalPIP
OASIS PortalPIP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPIP  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPIP
Mutations and Diseases : HGMDPIP
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPIP
DgiDB (Drug Gene Interaction Database)PIP
DoCM (Curated mutations)PIP
CIViC (Clinical Interpretations of Variants in Cancer)PIP
Cancer3DPIP
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176720   
Orphanet
DisGeNETPIP
MedgenPIP
Genetic Testing Registry PIP
NextProtP12273 [Medical]
GENETestsPIP
Target ValidationPIP
Huge Navigator PIP [HugePedia]
ClinGenPIP
Clinical trials, drugs, therapy
MyCancerGenomePIP
Protein Interactions : CTDPIP
Pharm GKB GenePA33326
PharosP12273
Clinical trialPIP
Miscellaneous
canSAR (ICR)PIP
HarmonizomePIP
DataMed IndexPIP
Probes
Litterature
PubMed103 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPIP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:25:23 CEST 2021

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