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PIP (prolactin induced protein)

Identity

Alias_namesprolactin-induced protein
Alias_symbol (synonym)GCDFP-15
GCDFP15
GPIP4
Other alias
HGNC (Hugo) PIP
LocusID (NCBI) 5304
Atlas_Id 45702
Location 7q34  [Link to chromosome band 7q34]
Location_base_pair Starts at 143132081 and ends at 143139741 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ALDH7A1 (5q23.2) / PIP (7q34)ALDH7A1 5q23.2 / PIP 7q34

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PIP   8993
Cards
Entrez_Gene (NCBI)PIP  5304  prolactin induced protein
AliasesGCDFP-15; GCDFP15; GPIP4
GeneCards (Weizmann)PIP
Ensembl hg19 (Hinxton)ENSG00000159763 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159763 [Gene_View]  chr7:143132081-143139741 [Contig_View]  PIP [Vega]
ICGC DataPortalENSG00000159763
TCGA cBioPortalPIP
AceView (NCBI)PIP
Genatlas (Paris)PIP
WikiGenes5304
SOURCE (Princeton)PIP
Genetics Home Reference (NIH)PIP
Genomic and cartography
GoldenPath hg38 (UCSC)PIP  -     chr7:143132081-143139741 +  7q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PIP  -     7q34   [Description]    (hg19-Feb_2009)
EnsemblPIP - 7q34 [CytoView hg19]  PIP - 7q34 [CytoView hg38]
Mapping of homologs : NCBIPIP [Mapview hg19]  PIP [Mapview hg38]
OMIM176720   
Gene and transcription
Genbank (Entrez)AK312227 BC010950 BC010951 CD723133 J03460
RefSeq transcript (Entrez)NM_002652
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PIP
Cluster EST : UnigeneHs.99949 [ NCBI ]
CGAP (NCI)Hs.99949
Alternative Splicing GalleryENSG00000159763
Gene ExpressionPIP [ NCBI-GEO ]   PIP [ EBI - ARRAY_EXPRESS ]   PIP [ SEEK ]   PIP [ MEM ]
Gene Expression Viewer (FireBrowse)PIP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5304
GTEX Portal (Tissue expression)PIP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP12273   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP12273  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP12273
Splice isoforms : SwissVarP12273
PhosPhoSitePlusP12273
Domains : Interpro (EBI)Ig_E-set    PIP   
Domain families : Pfam (Sanger)SVA (PF05326)   
Domain families : Pfam (NCBI)pfam05326   
Domain structure : Prodom (Prabi Lyon)SV_autoAg (PD021604)   
Conserved Domain (NCBI)PIP
DMDM Disease mutations5304
Blocks (Seattle)PIP
PDB (SRS)3ES6   
PDB (PDBSum)3ES6   
PDB (IMB)3ES6   
PDB (RSDB)3ES6   
Structural Biology KnowledgeBase3ES6   
SCOP (Structural Classification of Proteins)3ES6   
CATH (Classification of proteins structures)3ES6   
SuperfamilyP12273
Human Protein AtlasENSG00000159763
Peptide AtlasP12273
HPRD07179
IPIIPI00022974   
Protein Interaction databases
DIP (DOE-UCLA)P12273
IntAct (EBI)P12273
FunCoupENSG00000159763
BioGRIDPIP
STRING (EMBL)PIP
ZODIACPIP
Ontologies - Pathways
QuickGOP12273
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of bitter taste  retina homeostasis  glycoprotein binding  regulation of immune system process  actin binding  aspartic-type endopeptidase activity  protein binding  extracellular region  extracellular space  nucleus  proteolysis  positive regulation of gene expression  apical plasma membrane  IgG binding  protein dimerization activity  transmembrane transport  extracellular exosome  negative regulation of T cell apoptotic process  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of bitter taste  retina homeostasis  glycoprotein binding  regulation of immune system process  actin binding  aspartic-type endopeptidase activity  protein binding  extracellular region  extracellular space  nucleus  proteolysis  positive regulation of gene expression  apical plasma membrane  IgG binding  protein dimerization activity  transmembrane transport  extracellular exosome  negative regulation of T cell apoptotic process  
NDEx NetworkPIP
Atlas of Cancer Signalling NetworkPIP
Wikipedia pathwaysPIP
Orthology - Evolution
OrthoDB5304
GeneTree (enSembl)ENSG00000159763
Phylogenetic Trees/Animal Genes : TreeFamPIP
HOVERGENP12273
HOGENOMP12273
Homologs : HomoloGenePIP
Homology/Alignments : Family Browser (UCSC)PIP
Gene fusions - Rearrangements
Fusion : MitelmanALDH7A1/PIP [5q23.2/7q34]  [t(5;7)(q23;q34)]  
Fusion: TCGAALDH7A1 5q23.2 PIP 7q34 OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPIP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIP
dbVarPIP
ClinVarPIP
1000_GenomesPIP 
Exome Variant ServerPIP
ExAC (Exome Aggregation Consortium)PIP (select the gene name)
Genetic variants : HAPMAP5304
Genomic Variants (DGV)PIP [DGVbeta]
DECIPHERPIP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPIP 
Mutations
ICGC Data PortalPIP 
TCGA Data PortalPIP 
Broad Tumor PortalPIP
OASIS PortalPIP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPIP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPIP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PIP
DgiDB (Drug Gene Interaction Database)PIP
DoCM (Curated mutations)PIP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PIP (select a term)
intoGenPIP
Cancer3DPIP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176720   
Orphanet
MedgenPIP
Genetic Testing Registry PIP
NextProtP12273 [Medical]
TSGene5304
GENETestsPIP
Huge Navigator PIP [HugePedia]
snp3D : Map Gene to Disease5304
BioCentury BCIQPIP
ClinGenPIP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5304
Chemical/Pharm GKB GenePA33326
Clinical trialPIP
Miscellaneous
canSAR (ICR)PIP (select the gene name)
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePIP
EVEXPIP
GoPubMedPIP
iHOPPIP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:31:18 CEST 2017

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