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PIP4P2 (phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2)

Identity

Alias (NCBI)TMEM55A
HGNC (Hugo) PIP4P2
HGNC Alias symbDKFZp762O076
HGNC Alias nametype II phosphatidylinositol-4,5-bisphosphate 4-phosphatase
 type II PtdIns-4,5-P(2) 4-phosphatase
HGNC Previous nameTMEM55A
HGNC Previous nametransmembrane protein 55A
LocusID (NCBI) 55529
Atlas_Id 79315
Location 8q21.3  [Link to chromosome band 8q21]
Location_base_pair Starts at 90993803 and ends at 91040859 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

 

Nomenclature
HGNC (Hugo)PIP4P2   25452
Cards
Entrez_Gene (NCBI)PIP4P2    phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
AliasesTMEM55A
GeneCards (Weizmann)PIP4P2
Ensembl hg19 (Hinxton)ENSG00000155099 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155099 [Gene_View]  ENSG00000155099 [Sequence]  chr8:90993803-91040859 [Contig_View]  PIP4P2 [Vega]
ICGC DataPortalENSG00000155099
TCGA cBioPortalPIP4P2
AceView (NCBI)PIP4P2
Genatlas (Paris)PIP4P2
SOURCE (Princeton)PIP4P2
Genetics Home Reference (NIH)PIP4P2
Genomic and cartography
GoldenPath hg38 (UCSC)PIP4P2  -     chr8:90993803-91040859 -  8q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PIP4P2  -     8q21.3   [Description]    (hg19-Feb_2009)
GoldenPathPIP4P2 - 8q21.3 [CytoView hg19]  PIP4P2 - 8q21.3 [CytoView hg38]
ImmunoBaseENSG00000155099
Genome Data Viewer NCBIPIP4P2 [Mapview hg19]  
OMIM609864   
Gene and transcription
Genbank (Entrez)AK313783 AX775961 BC033892 CR749733 DA171968
RefSeq transcript (Entrez)NM_018710
Consensus coding sequences : CCDS (NCBI)PIP4P2
Gene ExpressionPIP4P2 [ NCBI-GEO ]   PIP4P2 [ EBI - ARRAY_EXPRESS ]   PIP4P2 [ SEEK ]   PIP4P2 [ MEM ]
Gene Expression Viewer (FireBrowse)PIP4P2 [ Firebrowse - Broad ]
GenevisibleExpression of PIP4P2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55529
GTEX Portal (Tissue expression)PIP4P2
Human Protein AtlasENSG00000155099-PIP4P2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N4L2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N4L2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N4L2
PhosPhoSitePlusQ8N4L2
Domains : Interpro (EBI)PtdIns-P2-Ptase   
Domain families : Pfam (Sanger)Tmemb_55A (PF09788)   
Domain families : Pfam (NCBI)pfam09788   
Conserved Domain (NCBI)PIP4P2
SuperfamilyQ8N4L2
AlphaFold pdb e-kbQ8N4L2   
Human Protein Atlas [tissue]ENSG00000155099-PIP4P2 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q8N4L2
IntAct (EBI)Q8N4L2
BioGRIDPIP4P2
STRING (EMBL)PIP4P2
ZODIACPIP4P2
Ontologies - Pathways
QuickGOQ8N4L2
Ontology : AmiGOprotein binding  lysosomal membrane  plasma membrane  integral component of membrane  phagocytic vesicle membrane  late endosome membrane  phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity  phosphatidylinositol dephosphorylation  negative regulation of phagocytosis  
Ontology : EGO-EBIprotein binding  lysosomal membrane  plasma membrane  integral component of membrane  phagocytic vesicle membrane  late endosome membrane  phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity  phosphatidylinositol dephosphorylation  negative regulation of phagocytosis  
NDEx NetworkPIP4P2
Atlas of Cancer Signalling NetworkPIP4P2
Wikipedia pathwaysPIP4P2
Orthology - Evolution
OrthoDB55529
GeneTree (enSembl)ENSG00000155099
Phylogenetic Trees/Animal Genes : TreeFamPIP4P2
Homologs : HomoloGenePIP4P2
Homology/Alignments : Family Browser (UCSC)PIP4P2
Gene fusions - Rearrangements
Fusion : QuiverPIP4P2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPIP4P2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIP4P2
dbVarPIP4P2
ClinVarPIP4P2
MonarchPIP4P2
1000_GenomesPIP4P2 
Exome Variant ServerPIP4P2
GNOMAD BrowserENSG00000155099
Varsome BrowserPIP4P2
ACMGPIP4P2 variants
VarityQ8N4L2
Genomic Variants (DGV)PIP4P2 [DGVbeta]
DECIPHERPIP4P2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPIP4P2 
Mutations
ICGC Data PortalPIP4P2 
TCGA Data PortalPIP4P2 
Broad Tumor PortalPIP4P2
OASIS PortalPIP4P2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPIP4P2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPIP4P2
Mutations and Diseases : HGMDPIP4P2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPIP4P2
DgiDB (Drug Gene Interaction Database)PIP4P2
DoCM (Curated mutations)PIP4P2
CIViC (Clinical Interpretations of Variants in Cancer)PIP4P2
Cancer3DPIP4P2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609864   
Orphanet
DisGeNETPIP4P2
MedgenPIP4P2
Genetic Testing Registry PIP4P2
NextProtQ8N4L2 [Medical]
GENETestsPIP4P2
Target ValidationPIP4P2
Huge Navigator PIP4P2 [HugePedia]
ClinGenPIP4P2
Clinical trials, drugs, therapy
MyCancerGenomePIP4P2
Protein Interactions : CTDPIP4P2
Pharm GKB GenePA142670771
PharosQ8N4L2
Clinical trialPIP4P2
Miscellaneous
canSAR (ICR)PIP4P2
HarmonizomePIP4P2
DataMed IndexPIP4P2
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPIP4P2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:16:14 CEST 2021

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