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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

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PIR (pirin (iron-binding nuclear protein))

Identity

Other names-
HGNC (Hugo) PIR
LocusID (NCBI) 8544
Location Xp22.2
Location_base_pair Starts at 15402924 and ends at 15511711 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PIR   30048
Cards
Entrez_Gene (NCBI)PIR  8544  pirin (iron-binding nuclear protein)
GeneCards (Weizmann)PIR
Ensembl hg19 (Hinxton)ENSG00000087842 [Gene_View]  chrX:15402924-15511711 [Contig_View]  PIR [Vega]
Ensembl hg38 (Hinxton)ENSG00000087842 [Gene_View]  chrX:15402924-15511711 [Contig_View]  PIR [Vega]
ICGC DataPortalENSG00000087842
cBioPortalPIR
AceView (NCBI)PIR
Genatlas (Paris)PIR
WikiGenes8544
SOURCE (Princeton)PIR
Genomic and cartography
GoldenPath hg19 (UCSC)PIR  -     chrX:15402924-15511711 -  Xp22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PIR  -     Xp22.2   [Description]    (hg38-Dec_2013)
EnsemblPIR - Xp22.2 [CytoView hg19]  PIR - Xp22.2 [CytoView hg38]
Mapping of homologs : NCBIPIR [Mapview hg19]  PIR [Mapview hg38]
OMIM603329   
Gene and transcription
Genbank (Entrez)AK309656 BC002517 BT019583 BT019584 CR541822
RefSeq transcript (Entrez)NM_001018109 NM_003662
RefSeq genomic (Entrez)AC_000155 NC_000023 NC_018934 NG_012549 NT_167197 NW_001842360 NW_004929438
Consensus coding sequences : CCDS (NCBI)PIR
Cluster EST : UnigeneHs.732521 [ NCBI ]
CGAP (NCI)Hs.732521
Alternative Splicing : Fast-db (Paris)GSHG0031987
Alternative Splicing GalleryENSG00000087842
Gene ExpressionPIR [ NCBI-GEO ]     PIR [ SEEK ]   PIR [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00625 (Uniprot)
NextProtO00625  [Medical]
With graphics : InterProO00625
Splice isoforms : SwissVarO00625 (Swissvar)
Catalytic activity : Enzyme1.13.11.24 [ Enzyme-Expasy ]   1.13.11.241.13.11.24 [ IntEnz-EBI ]   1.13.11.24 [ BRENDA ]   1.13.11.24 [ KEGG ]   
Domains : Interpro (EBI)Pirin    Pirin_C_dom    Pirin_N_dom    RmlC-like_jellyroll    RmlC_Cupin   
Related proteins : CluSTrO00625
Domain families : Pfam (Sanger)Pirin (PF02678)    Pirin_C (PF05726)   
Domain families : Pfam (NCBI)pfam02678    pfam05726   
DMDM Disease mutations8544
Blocks (Seattle)O00625
PDB (SRS)1J1L    3ACL    4ERO    4EWA    4EWD    4EWE    4GUL    4HLT   
PDB (PDBSum)1J1L    3ACL    4ERO    4EWA    4EWD    4EWE    4GUL    4HLT   
PDB (IMB)1J1L    3ACL    4ERO    4EWA    4EWD    4EWE    4GUL    4HLT   
PDB (RSDB)1J1L    3ACL    4ERO    4EWA    4EWD    4EWE    4GUL    4HLT   
Human Protein AtlasENSG00000087842
Peptide AtlasO00625
HPRD04510
IPIIPI00012575   
Protein Interaction databases
DIP (DOE-UCLA)O00625
IntAct (EBI)O00625
FunCoupENSG00000087842
BioGRIDPIR
IntegromeDBPIR
STRING (EMBL)PIR
Ontologies - Pathways
QuickGOO00625
Ontology : AmiGOtranscription cofactor activity  protein binding  nucleus  cytoplasm  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  quercetin 2,3-dioxygenase activity  monocyte differentiation  metal ion binding  oxidation-reduction process  
Ontology : EGO-EBItranscription cofactor activity  protein binding  nucleus  cytoplasm  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  quercetin 2,3-dioxygenase activity  monocyte differentiation  metal ion binding  oxidation-reduction process  
Pathways : BIOCARTAY branching of actin filaments [Genes]   
Protein Interaction DatabasePIR
DoCM (Curated mutations)PIR
Wikipedia pathwaysPIR
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerPIR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIR
dbVarPIR
ClinVarPIR
1000_GenomesPIR 
Exome Variant ServerPIR
SNP (GeneSNP Utah)PIR
SNP : HGBasePIR
Genetic variants : HAPMAPPIR
Genomic Variants (DGV)PIR [DGVbeta]
Mutations
ICGC Data PortalENSG00000087842 
Somatic Mutations in Cancer : COSMICPIR 
CONAN: Copy Number AnalysisPIR 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)X:15402924-15511711
Mutations and Diseases : HGMDPIR
OMIM603329   
MedgenPIR
NextProtO00625 [Medical]
GENETestsPIR
Disease Genetic AssociationPIR
Huge Navigator PIR [HugePedia]  PIR [HugeCancerGEM]
snp3D : Map Gene to Disease8544
DGIdb (Drug Gene Interaction db)PIR
General knowledge
Homologs : HomoloGenePIR
Homology/Alignments : Family Browser (UCSC)PIR
Phylogenetic Trees/Animal Genes : TreeFamPIR
Chemical/Protein Interactions : CTD8544
Chemical/Pharm GKB GenePA134870022
Clinical trialPIR
Cancer Resource (Charite)ENSG00000087842
Other databases
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
CoreMinePIR
GoPubMedPIR
iHOPPIR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 17:59:59 CET 2015

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jlhuret@AtlasGeneticsOncology.org.