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PIR (pirin)

Identity

Other names-
HGNC (Hugo) PIR
LocusID (NCBI) 8544
Atlas_Id 41722
Location Xp22.2  [Link to chromosome band Xp22]
Location_base_pair Starts at 15402924 and ends at 15511711 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(8;17)(q24;q22) ???BCL3/MYC

External links

Nomenclature
HGNC (Hugo)PIR   30048
Cards
Entrez_Gene (NCBI)PIR  8544  pirin
Aliases
GeneCards (Weizmann)PIR
Ensembl hg19 (Hinxton)ENSG00000087842 [Gene_View]  chrX:15402924-15511711 [Contig_View]  PIR [Vega]
Ensembl hg38 (Hinxton)ENSG00000087842 [Gene_View]  chrX:15402924-15511711 [Contig_View]  PIR [Vega]
ICGC DataPortalENSG00000087842
TCGA cBioPortalPIR
AceView (NCBI)PIR
Genatlas (Paris)PIR
WikiGenes8544
SOURCE (Princeton)PIR
Genomic and cartography
GoldenPath hg19 (UCSC)PIR  -     chrX:15402924-15511711 -  Xp22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PIR  -     Xp22.2   [Description]    (hg38-Dec_2013)
EnsemblPIR - Xp22.2 [CytoView hg19]  PIR - Xp22.2 [CytoView hg38]
Mapping of homologs : NCBIPIR [Mapview hg19]  PIR [Mapview hg38]
OMIM300931   
Gene and transcription
Genbank (Entrez)AK309656 BC002517 BT019583 BT019584 CR541822
RefSeq transcript (Entrez)NM_001018109 NM_003662
RefSeq genomic (Entrez)NC_000023 NC_018934 NG_012549 NT_167197 NW_004929438
Consensus coding sequences : CCDS (NCBI)PIR
Cluster EST : UnigeneHs.732521 [ NCBI ]
CGAP (NCI)Hs.732521
Alternative Splicing GalleryENSG00000087842
Gene ExpressionPIR [ NCBI-GEO ]   PIR [ EBI - ARRAY_EXPRESS ]   PIR [ SEEK ]   PIR [ MEM ]
Gene Expression Viewer (FireBrowse)PIR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8544
GTEX Portal (Tissue expression)PIR
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00625 (Uniprot)
NextProtO00625  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00625
Splice isoforms : SwissVarO00625 (Swissvar)
Catalytic activity : Enzyme1.13.11.24 [ Enzyme-Expasy ]   1.13.11.241.13.11.24 [ IntEnz-EBI ]   1.13.11.24 [ BRENDA ]   1.13.11.24 [ KEGG ]   
PhosPhoSitePlusO00625
Domains : Interpro (EBI)Pirin    Pirin_C_dom    Pirin_N_dom    RmlC-like_jellyroll    RmlC_Cupin   
Domain families : Pfam (Sanger)Pirin (PF02678)    Pirin_C (PF05726)   
Domain families : Pfam (NCBI)pfam02678    pfam05726   
DMDM Disease mutations8544
Blocks (Seattle)PIR
PDB (SRS)1J1L    3ACL    4ERO    4EWA    4EWD    4EWE    4GUL    4HLT   
PDB (PDBSum)1J1L    3ACL    4ERO    4EWA    4EWD    4EWE    4GUL    4HLT   
PDB (IMB)1J1L    3ACL    4ERO    4EWA    4EWD    4EWE    4GUL    4HLT   
PDB (RSDB)1J1L    3ACL    4ERO    4EWA    4EWD    4EWE    4GUL    4HLT   
Structural Biology KnowledgeBase1J1L    3ACL    4ERO    4EWA    4EWD    4EWE    4GUL    4HLT   
SCOP (Structural Classification of Proteins)1J1L    3ACL    4ERO    4EWA    4EWD    4EWE    4GUL    4HLT   
CATH (Classification of proteins structures)1J1L    3ACL    4ERO    4EWA    4EWD    4EWE    4GUL    4HLT   
SuperfamilyO00625
Human Protein AtlasENSG00000087842
Peptide AtlasO00625
HPRD04510
IPIIPI00012575   
Protein Interaction databases
DIP (DOE-UCLA)O00625
IntAct (EBI)O00625
FunCoupENSG00000087842
BioGRIDPIR
STRING (EMBL)PIR
ZODIACPIR
Ontologies - Pathways
QuickGOO00625
Ontology : AmiGOtranscription cofactor activity  protein binding  nucleus  cytoplasm  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  quercetin 2,3-dioxygenase activity  monocyte differentiation  metal ion binding  oxidation-reduction process  
Ontology : EGO-EBItranscription cofactor activity  protein binding  nucleus  cytoplasm  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  quercetin 2,3-dioxygenase activity  monocyte differentiation  metal ion binding  oxidation-reduction process  
Pathways : BIOCARTAY branching of actin filaments [Genes]   
NDEx NetworkPIR
Atlas of Cancer Signalling NetworkPIR
Wikipedia pathwaysPIR
Orthology - Evolution
OrthoDB8544
GeneTree (enSembl)ENSG00000087842
Phylogenetic Trees/Animal Genes : TreeFamPIR
Homologs : HomoloGenePIR
Homology/Alignments : Family Browser (UCSC)PIR
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerPIR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PIR
dbVarPIR
ClinVarPIR
1000_GenomesPIR 
Exome Variant ServerPIR
ExAC (Exome Aggregation Consortium)PIR (select the gene name)
Genetic variants : HAPMAP8544
Genomic Variants (DGV)PIR [DGVbeta]
Mutations
ICGC Data PortalPIR 
TCGA Data PortalPIR 
Broad Tumor PortalPIR
OASIS PortalPIR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPIR 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch PIR
DgiDB (Drug Gene Interaction Database)PIR
DoCM (Curated mutations)PIR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PIR (select a term)
intoGenPIR
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)X:15402924-15511711  ENSG00000087842
CONAN: Copy Number AnalysisPIR 
Mutations and Diseases : HGMDPIR
OMIM300931   
MedgenPIR
Genetic Testing Registry PIR
NextProtO00625 [Medical]
TSGene8544
GENETestsPIR
Huge Navigator PIR [HugePedia]
snp3D : Map Gene to Disease8544
BioCentury BCIQPIR
ClinGenPIR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8544
Chemical/Pharm GKB GenePA134870022
Clinical trialPIR
Miscellaneous
canSAR (ICR)PIR (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePIR
EVEXPIR
GoPubMedPIR
iHOPPIR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 19 19:07:13 CEST 2016

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