Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel)

Identity

Alias (NCBI)TRPP5
HGNC (Hugo) PKD2L2
HGNC Alias symbTRPP5
HGNC Alias nametransient receptor potential cation channel subfamily P member 5
HGNC Previous namepolycystic kidney disease 2-like 2
LocusID (NCBI) 27039
Atlas_Id 71941
Location 5q31.2  [Link to chromosome band 5q31]
Location_base_pair Starts at 137889457 and ends at 137940471 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PKD2L2   9012
Cards
Entrez_Gene (NCBI)PKD2L2    polycystin 2 like 2, transient receptor potential cation channel
AliasesTRPP5
GeneCards (Weizmann)PKD2L2
Ensembl hg19 (Hinxton)ENSG00000078795 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000078795 [Gene_View]  ENSG00000078795 [Sequence]  chr5:137889457-137940471 [Contig_View]  PKD2L2 [Vega]
ICGC DataPortalENSG00000078795
TCGA cBioPortalPKD2L2
AceView (NCBI)PKD2L2
Genatlas (Paris)PKD2L2
SOURCE (Princeton)PKD2L2
Genetics Home Reference (NIH)PKD2L2
Genomic and cartography
GoldenPath hg38 (UCSC)PKD2L2  -     chr5:137889457-137940471 +  5q31.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PKD2L2  -     5q31.2   [Description]    (hg19-Feb_2009)
GoldenPathPKD2L2 - 5q31.2 [CytoView hg19]  PKD2L2 - 5q31.2 [CytoView hg38]
ImmunoBaseENSG00000078795
Genome Data Viewer NCBIPKD2L2 [Mapview hg19]  
OMIM604669   
Gene and transcription
Genbank (Entrez)AF118125 AF182034 AK301924 BC034619 BC038714
RefSeq transcript (Entrez)NM_001258448 NM_001258449 NM_001300921 NM_014386
Consensus coding sequences : CCDS (NCBI)PKD2L2
Gene ExpressionPKD2L2 [ NCBI-GEO ]   PKD2L2 [ EBI - ARRAY_EXPRESS ]   PKD2L2 [ SEEK ]   PKD2L2 [ MEM ]
Gene Expression Viewer (FireBrowse)PKD2L2 [ Firebrowse - Broad ]
GenevisibleExpression of PKD2L2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27039
GTEX Portal (Tissue expression)PKD2L2
Human Protein AtlasENSG00000078795-PKD2L2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZM6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZM6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZM6
PhosPhoSitePlusQ9NZM6
Domains : Interpro (EBI)PKD1_2_channel    PKD_2   
Domain families : Pfam (Sanger)PKD_channel (PF08016)   
Domain families : Pfam (NCBI)pfam08016   
Conserved Domain (NCBI)PKD2L2
SuperfamilyQ9NZM6
AlphaFold pdb e-kbQ9NZM6   
Human Protein Atlas [tissue]ENSG00000078795-PKD2L2 [tissue]
HPRD05238
Protein Interaction databases
DIP (DOE-UCLA)Q9NZM6
IntAct (EBI)Q9NZM6
BioGRIDPKD2L2
STRING (EMBL)PKD2L2
ZODIACPKD2L2
Ontologies - Pathways
QuickGOQ9NZM6
Ontology : AmiGOcalcium channel activity  calcium ion binding  biological_process  membrane  integral component of membrane  detection of mechanical stimulus  calcium ion transmembrane transport  
Ontology : EGO-EBIcalcium channel activity  calcium ion binding  biological_process  membrane  integral component of membrane  detection of mechanical stimulus  calcium ion transmembrane transport  
NDEx NetworkPKD2L2
Atlas of Cancer Signalling NetworkPKD2L2
Wikipedia pathwaysPKD2L2
Orthology - Evolution
OrthoDB27039
GeneTree (enSembl)ENSG00000078795
Phylogenetic Trees/Animal Genes : TreeFamPKD2L2
Homologs : HomoloGenePKD2L2
Homology/Alignments : Family Browser (UCSC)PKD2L2
Gene fusions - Rearrangements
Fusion : QuiverPKD2L2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPKD2L2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PKD2L2
dbVarPKD2L2
ClinVarPKD2L2
MonarchPKD2L2
1000_GenomesPKD2L2 
Exome Variant ServerPKD2L2
GNOMAD BrowserENSG00000078795
Varsome BrowserPKD2L2
ACMGPKD2L2 variants
VarityQ9NZM6
Genomic Variants (DGV)PKD2L2 [DGVbeta]
DECIPHERPKD2L2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPKD2L2 
Mutations
ICGC Data PortalPKD2L2 
TCGA Data PortalPKD2L2 
Broad Tumor PortalPKD2L2
OASIS PortalPKD2L2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPKD2L2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPKD2L2
Mutations and Diseases : HGMDPKD2L2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPKD2L2
DgiDB (Drug Gene Interaction Database)PKD2L2
DoCM (Curated mutations)PKD2L2
CIViC (Clinical Interpretations of Variants in Cancer)PKD2L2
Cancer3DPKD2L2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604669   
Orphanet
DisGeNETPKD2L2
MedgenPKD2L2
Genetic Testing Registry PKD2L2
NextProtQ9NZM6 [Medical]
GENETestsPKD2L2
Target ValidationPKD2L2
Huge Navigator PKD2L2 [HugePedia]
ClinGenPKD2L2
Clinical trials, drugs, therapy
MyCancerGenomePKD2L2
Protein Interactions : CTDPKD2L2
Pharm GKB GenePA33345
PharosQ9NZM6
Clinical trialPKD2L2
Miscellaneous
canSAR (ICR)PKD2L2
HarmonizomePKD2L2
DataMed IndexPKD2L2
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPKD2L2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:16:18 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.