PKIG (cAMP-dependent protein kinase inhibitor gamma)

2014-11-01  

Identity

HGNC
LOCATION
20q13.12
LOCUSID
ALIAS
PKI-gamma
FUSION GENES

Other Information

Locus ID:

NCBI: 11142
MIM: 604932
HGNC: 9019
Ensembl: ENSG00000168734

Variants:

dbSNP: 11142
ClinVar: 11142
TCGA: ENSG00000168734
COSMIC: PKIG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168734ENST00000349959Q9Y2B9
ENSG00000168734ENST00000349959Q549H9
ENSG00000168734ENST00000372886Q9Y2B9
ENSG00000168734ENST00000372886Q549H9
ENSG00000168734ENST00000372887Q5H937
ENSG00000168734ENST00000372889Q9Y2B9
ENSG00000168734ENST00000372889Q549H9
ENSG00000168734ENST00000372891Q9Y2B9
ENSG00000168734ENST00000372891Q549H9
ENSG00000168734ENST00000372892Q9Y2B9
ENSG00000168734ENST00000372892Q549H9
ENSG00000168734ENST00000372894Q9Y2B9
ENSG00000168734ENST00000372894Q549H9

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
92184521997Characterization of PKIgamma, a novel isoform of the protein kinase inhibitor of cAMP-dependent protein kinase.16
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
117427982002Vascular endothelial cells express isoforms of protein kinase A inhibitor.8
168704892006Downregulation of cAMP-dependent protein kinase inhibitor gamma is required for BMP-2-induced osteoblastic differentiation.7
239636832013Protein kinase inhibitor γ reciprocally regulates osteoblast and adipocyte differentiation by downregulating leukemia inhibitory factor.2

Citation

Dessen P

PKIG (cAMP-dependent protein kinase inhibitor gamma)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71945/pkig