Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PKNOX2 (PBX/knotted 1 homeobox 2)

Identity

Other aliasPREP2
HGNC (Hugo) PKNOX2
LocusID (NCBI) 63876
Atlas_Id 71947
Location 11q24.2  [Link to chromosome band 11q24]
Location_base_pair Starts at 125034559 and ends at 125303285 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PKNOX2 (11q24.2) / LDAH (2p24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PKNOX2   16714
Cards
Entrez_Gene (NCBI)PKNOX2  63876  PBX/knotted 1 homeobox 2
AliasesPREP2
GeneCards (Weizmann)PKNOX2
Ensembl hg19 (Hinxton)ENSG00000165495 [Gene_View]  chr11:125034559-125303285 [Contig_View]  PKNOX2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000165495 [Gene_View]  chr11:125034559-125303285 [Contig_View]  PKNOX2 [Vega]
ICGC DataPortalENSG00000165495
TCGA cBioPortalPKNOX2
AceView (NCBI)PKNOX2
Genatlas (Paris)PKNOX2
WikiGenes63876
SOURCE (Princeton)PKNOX2
Genetics Home Reference (NIH)PKNOX2
Genomic and cartography
GoldenPath hg19 (UCSC)PKNOX2  -     chr11:125034559-125303285 +  11q24.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PKNOX2  -     11q24.2   [Description]    (hg38-Dec_2013)
EnsemblPKNOX2 - 11q24.2 [CytoView hg19]  PKNOX2 - 11q24.2 [CytoView hg38]
Mapping of homologs : NCBIPKNOX2 [Mapview hg19]  PKNOX2 [Mapview hg38]
OMIM613066   
Gene and transcription
Genbank (Entrez)AB065001 AJ417081 AK023136 AK023792 AK056506
RefSeq transcript (Entrez)NM_022062
RefSeq genomic (Entrez)NC_000011 NC_018922 NT_033899 NW_004929381
Consensus coding sequences : CCDS (NCBI)PKNOX2
Cluster EST : UnigeneHs.278564 [ NCBI ]
CGAP (NCI)Hs.278564
Alternative Splicing GalleryENSG00000165495
Gene ExpressionPKNOX2 [ NCBI-GEO ]   PKNOX2 [ EBI - ARRAY_EXPRESS ]   PKNOX2 [ SEEK ]   PKNOX2 [ MEM ]
Gene Expression Viewer (FireBrowse)PKNOX2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)63876
GTEX Portal (Tissue expression)PKNOX2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96KN3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96KN3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96KN3
Splice isoforms : SwissVarQ96KN3
PhosPhoSitePlusQ96KN3
Domaine pattern : Prosite (Expaxy)HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox_dom    Homeobox_KN_domain    Homeodomain-like   
Domain families : Pfam (Sanger)Homeobox_KN (PF05920)   
Domain families : Pfam (NCBI)pfam05920   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)PKNOX2
DMDM Disease mutations63876
Blocks (Seattle)PKNOX2
SuperfamilyQ96KN3
Human Protein AtlasENSG00000165495
Peptide AtlasQ96KN3
HPRD17857
IPIIPI00414972   IPI00984028   IPI01014147   IPI01010952   IPI00984837   IPI00982831   IPI00983435   
Protein Interaction databases
DIP (DOE-UCLA)Q96KN3
IntAct (EBI)Q96KN3
FunCoupENSG00000165495
BioGRIDPKNOX2
STRING (EMBL)PKNOX2
ZODIACPKNOX2
Ontologies - Pathways
QuickGOQ96KN3
Ontology : AmiGOactin monomer binding  nucleus  cytoplasm  regulation of transcription from RNA polymerase II promoter  actin cytoskeleton  microtubule cytoskeleton  sequence-specific DNA binding  actin filament binding  
Ontology : EGO-EBIactin monomer binding  nucleus  cytoplasm  regulation of transcription from RNA polymerase II promoter  actin cytoskeleton  microtubule cytoskeleton  sequence-specific DNA binding  actin filament binding  
NDEx NetworkPKNOX2
Atlas of Cancer Signalling NetworkPKNOX2
Wikipedia pathwaysPKNOX2
Orthology - Evolution
OrthoDB63876
GeneTree (enSembl)ENSG00000165495
Phylogenetic Trees/Animal Genes : TreeFamPKNOX2
HOVERGENQ96KN3
HOGENOMQ96KN3
Homologs : HomoloGenePKNOX2
Homology/Alignments : Family Browser (UCSC)PKNOX2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPKNOX2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PKNOX2
dbVarPKNOX2
ClinVarPKNOX2
1000_GenomesPKNOX2 
Exome Variant ServerPKNOX2
ExAC (Exome Aggregation Consortium)PKNOX2 (select the gene name)
Genetic variants : HAPMAP63876
Genomic Variants (DGV)PKNOX2 [DGVbeta]
DECIPHER (Syndromes)11:125034559-125303285  ENSG00000165495
CONAN: Copy Number AnalysisPKNOX2 
Mutations
ICGC Data PortalPKNOX2 
TCGA Data PortalPKNOX2 
Broad Tumor PortalPKNOX2
OASIS PortalPKNOX2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPKNOX2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPKNOX2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PKNOX2
DgiDB (Drug Gene Interaction Database)PKNOX2
DoCM (Curated mutations)PKNOX2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PKNOX2 (select a term)
intoGenPKNOX2
Cancer3DPKNOX2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613066   
Orphanet
MedgenPKNOX2
Genetic Testing Registry PKNOX2
NextProtQ96KN3 [Medical]
TSGene63876
GENETestsPKNOX2
Huge Navigator PKNOX2 [HugePedia]
snp3D : Map Gene to Disease63876
BioCentury BCIQPKNOX2
ClinGenPKNOX2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD63876
Chemical/Pharm GKB GenePA33355
Clinical trialPKNOX2
Miscellaneous
canSAR (ICR)PKNOX2 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePKNOX2
EVEXPKNOX2
GoPubMedPKNOX2
iHOPPKNOX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:38:46 CET 2017

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