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PLA1A (phospholipase A1 member A)

Identity

Alias_symbol (synonym)ps-PLA1
Other aliasPS-PLA1
PSPLA1
HGNC (Hugo) PLA1A
LocusID (NCBI) 51365
Atlas_Id 55217
Location 3q13.33  [Link to chromosome band 3q13]
Location_base_pair Starts at 119316695 and ends at 119348658 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLA1A   17661
Cards
Entrez_Gene (NCBI)PLA1A  51365  phospholipase A1 member A
AliasesPS-PLA1; PSPLA1
GeneCards (Weizmann)PLA1A
Ensembl hg19 (Hinxton)ENSG00000144837 [Gene_View]  chr3:119316695-119348658 [Contig_View]  PLA1A [Vega]
Ensembl hg38 (Hinxton)ENSG00000144837 [Gene_View]  chr3:119316695-119348658 [Contig_View]  PLA1A [Vega]
ICGC DataPortalENSG00000144837
TCGA cBioPortalPLA1A
AceView (NCBI)PLA1A
Genatlas (Paris)PLA1A
WikiGenes51365
SOURCE (Princeton)PLA1A
Genetics Home Reference (NIH)PLA1A
Genomic and cartography
GoldenPath hg19 (UCSC)PLA1A  -     chr3:119316695-119348658 +  3q13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PLA1A  -     3q13.33   [Description]    (hg38-Dec_2013)
EnsemblPLA1A - 3q13.33 [CytoView hg19]  PLA1A - 3q13.33 [CytoView hg38]
Mapping of homologs : NCBIPLA1A [Mapview hg19]  PLA1A [Mapview hg38]
OMIM607460   
Gene and transcription
Genbank (Entrez)AF035268 AF035269 AK222705 AK301880 AK313519
RefSeq transcript (Entrez)NM_001206960 NM_001206961 NM_001293225 NM_015900
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_029696 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)PLA1A
Cluster EST : UnigeneHs.437451 [ NCBI ]
CGAP (NCI)Hs.437451
Alternative Splicing GalleryENSG00000144837
Gene ExpressionPLA1A [ NCBI-GEO ]   PLA1A [ EBI - ARRAY_EXPRESS ]   PLA1A [ SEEK ]   PLA1A [ MEM ]
Gene Expression Viewer (FireBrowse)PLA1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51365
GTEX Portal (Tissue expression)PLA1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ53H76   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ53H76  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ53H76
Splice isoforms : SwissVarQ53H76
Catalytic activity : Enzyme3.1.1.- [ Enzyme-Expasy ]   3.1.1.-3.1.1.- [ IntEnz-EBI ]   3.1.1.- [ BRENDA ]   3.1.1.- [ KEGG ]   
PhosPhoSitePlusQ53H76
Domaine pattern : Prosite (Expaxy)LIPASE_SER (PS00120)   
Domains : Interpro (EBI)AB_hydrolase    Lipase_LIPH    Lipase_N    TAG_lipase   
Domain families : Pfam (Sanger)Lipase (PF00151)   
Domain families : Pfam (NCBI)pfam00151   
Conserved Domain (NCBI)PLA1A
DMDM Disease mutations51365
Blocks (Seattle)PLA1A
SuperfamilyQ53H76
Human Protein AtlasENSG00000144837
Peptide AtlasQ53H76
HPRD07078
IPIIPI00642790   IPI00827534   IPI00794633   IPI00945583   IPI00977738   IPI00796037   
Protein Interaction databases
DIP (DOE-UCLA)Q53H76
IntAct (EBI)Q53H76
FunCoupENSG00000144837
BioGRIDPLA1A
STRING (EMBL)PLA1A
ZODIACPLA1A
Ontologies - Pathways
QuickGOQ53H76
Ontology : AmiGOacrosomal membrane  lipid metabolic process  phosphatidylserine metabolic process  phosphatidylcholine 1-acylhydrolase activity  lipid catabolic process  extracellular exosome  
Ontology : EGO-EBIacrosomal membrane  lipid metabolic process  phosphatidylserine metabolic process  phosphatidylcholine 1-acylhydrolase activity  lipid catabolic process  extracellular exosome  
Pathways : KEGGRas signaling pathway   
NDEx NetworkPLA1A
Atlas of Cancer Signalling NetworkPLA1A
Wikipedia pathwaysPLA1A
Orthology - Evolution
OrthoDB51365
GeneTree (enSembl)ENSG00000144837
Phylogenetic Trees/Animal Genes : TreeFamPLA1A
HOVERGENQ53H76
HOGENOMQ53H76
Homologs : HomoloGenePLA1A
Homology/Alignments : Family Browser (UCSC)PLA1A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLA1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLA1A
dbVarPLA1A
ClinVarPLA1A
1000_GenomesPLA1A 
Exome Variant ServerPLA1A
ExAC (Exome Aggregation Consortium)PLA1A (select the gene name)
Genetic variants : HAPMAP51365
Genomic Variants (DGV)PLA1A [DGVbeta]
DECIPHER (Syndromes)3:119316695-119348658  ENSG00000144837
CONAN: Copy Number AnalysisPLA1A 
Mutations
ICGC Data PortalPLA1A 
TCGA Data PortalPLA1A 
Broad Tumor PortalPLA1A
OASIS PortalPLA1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLA1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPLA1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PLA1A
DgiDB (Drug Gene Interaction Database)PLA1A
DoCM (Curated mutations)PLA1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLA1A (select a term)
intoGenPLA1A
Cancer3DPLA1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607460   
Orphanet
MedgenPLA1A
Genetic Testing Registry PLA1A
NextProtQ53H76 [Medical]
TSGene51365
GENETestsPLA1A
Huge Navigator PLA1A [HugePedia]
snp3D : Map Gene to Disease51365
BioCentury BCIQPLA1A
ClinGenPLA1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51365
Chemical/Pharm GKB GenePA134955851
Clinical trialPLA1A
Miscellaneous
canSAR (ICR)PLA1A (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLA1A
EVEXPLA1A
GoPubMedPLA1A
iHOPPLA1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:21:37 CET 2017

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