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PLA2G12B (phospholipase A2 group XIIB)

Identity

Alias_namesPLA2G13
phospholipase A2, group XIII
phospholipase A2, group XIIB
Other aliasFKSG71
GXIIB
GXIIIsPLA2
sPLA2-GXIIB
HGNC (Hugo) PLA2G12B
LocusID (NCBI) 84647
Atlas_Id 71951
Location 10q22.1  [Link to chromosome band 10q22]
Location_base_pair Starts at 72934762 and ends at 72954819 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AMMECR1 (Xq23) / PLA2G12B (10q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLA2G12B   18555
Cards
Entrez_Gene (NCBI)PLA2G12B  84647  phospholipase A2 group XIIB
AliasesFKSG71; GXIIB; GXIIIsPLA2; PLA2G13; 
sPLA2-GXIIB
GeneCards (Weizmann)PLA2G12B
Ensembl hg19 (Hinxton)ENSG00000138308 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138308 [Gene_View]  chr10:72934762-72954819 [Contig_View]  PLA2G12B [Vega]
ICGC DataPortalENSG00000138308
TCGA cBioPortalPLA2G12B
AceView (NCBI)PLA2G12B
Genatlas (Paris)PLA2G12B
WikiGenes84647
SOURCE (Princeton)PLA2G12B
Genetics Home Reference (NIH)PLA2G12B
Genomic and cartography
GoldenPath hg38 (UCSC)PLA2G12B  -     chr10:72934762-72954819 -  10q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLA2G12B  -     10q22.1   [Description]    (hg19-Feb_2009)
EnsemblPLA2G12B - 10q22.1 [CytoView hg19]  PLA2G12B - 10q22.1 [CytoView hg38]
Mapping of homologs : NCBIPLA2G12B [Mapview hg19]  PLA2G12B [Mapview hg38]
OMIM611653   
Gene and transcription
Genbank (Entrez)AF339053 AF349540 AK311349 AK313712 AY358032
RefSeq transcript (Entrez)NM_001318124 NM_001318125 NM_032562
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLA2G12B
Cluster EST : UnigeneHs.333175 [ NCBI ]
CGAP (NCI)Hs.333175
Alternative Splicing GalleryENSG00000138308
Gene ExpressionPLA2G12B [ NCBI-GEO ]   PLA2G12B [ EBI - ARRAY_EXPRESS ]   PLA2G12B [ SEEK ]   PLA2G12B [ MEM ]
Gene Expression Viewer (FireBrowse)PLA2G12B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84647
GTEX Portal (Tissue expression)PLA2G12B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BX93   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BX93  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BX93
Splice isoforms : SwissVarQ9BX93
PhosPhoSitePlusQ9BX93
Domaine pattern : Prosite (Expaxy)ER_TARGET (PS00014)   
Domains : Interpro (EBI)PLA2G12    PLipase_A2_dom   
Domain families : Pfam (Sanger)PLA2G12 (PF06951)   
Domain families : Pfam (NCBI)pfam06951   
Conserved Domain (NCBI)PLA2G12B
DMDM Disease mutations84647
Blocks (Seattle)PLA2G12B
SuperfamilyQ9BX93
Human Protein AtlasENSG00000138308
Peptide AtlasQ9BX93
HPRD10155
IPIIPI00000240   
Protein Interaction databases
DIP (DOE-UCLA)Q9BX93
IntAct (EBI)Q9BX93
FunCoupENSG00000138308
BioGRIDPLA2G12B
STRING (EMBL)PLA2G12B
ZODIACPLA2G12B
Ontologies - Pathways
QuickGOQ9BX93
Ontology : AmiGOphospholipase A2 activity  calcium ion binding  extracellular region  phospholipid metabolic process  lipid catabolic process  arachidonic acid secretion  
Ontology : EGO-EBIphospholipase A2 activity  calcium ion binding  extracellular region  phospholipid metabolic process  lipid catabolic process  arachidonic acid secretion  
Pathways : KEGGGlycerophospholipid metabolism    Ether lipid metabolism    Arachidonic acid metabolism    Linoleic acid metabolism    alpha-Linolenic acid metabolism    Ras signaling pathway    Vascular smooth muscle contraction    Pancreatic secretion    Fat digestion and absorption   
NDEx NetworkPLA2G12B
Atlas of Cancer Signalling NetworkPLA2G12B
Wikipedia pathwaysPLA2G12B
Orthology - Evolution
OrthoDB84647
GeneTree (enSembl)ENSG00000138308
Phylogenetic Trees/Animal Genes : TreeFamPLA2G12B
HOVERGENQ9BX93
HOGENOMQ9BX93
Homologs : HomoloGenePLA2G12B
Homology/Alignments : Family Browser (UCSC)PLA2G12B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLA2G12B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLA2G12B
dbVarPLA2G12B
ClinVarPLA2G12B
1000_GenomesPLA2G12B 
Exome Variant ServerPLA2G12B
ExAC (Exome Aggregation Consortium)PLA2G12B (select the gene name)
Genetic variants : HAPMAP84647
Genomic Variants (DGV)PLA2G12B [DGVbeta]
DECIPHERPLA2G12B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLA2G12B 
Mutations
ICGC Data PortalPLA2G12B 
TCGA Data PortalPLA2G12B 
Broad Tumor PortalPLA2G12B
OASIS PortalPLA2G12B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLA2G12B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPLA2G12B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PLA2G12B
DgiDB (Drug Gene Interaction Database)PLA2G12B
DoCM (Curated mutations)PLA2G12B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLA2G12B (select a term)
intoGenPLA2G12B
Cancer3DPLA2G12B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611653   
Orphanet
MedgenPLA2G12B
Genetic Testing Registry PLA2G12B
NextProtQ9BX93 [Medical]
TSGene84647
GENETestsPLA2G12B
Target ValidationPLA2G12B
Huge Navigator PLA2G12B [HugePedia]
snp3D : Map Gene to Disease84647
BioCentury BCIQPLA2G12B
ClinGenPLA2G12B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84647
Chemical/Pharm GKB GenePA38573
Clinical trialPLA2G12B
Miscellaneous
canSAR (ICR)PLA2G12B (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLA2G12B
EVEXPLA2G12B
GoPubMedPLA2G12B
iHOPPLA2G12B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:34:39 CEST 2017

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