Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PLA2G16 (phospholipase A2 group XVI)

Identity

Alias_namesHRASLS3
HRAS-like suppressor 3
phospholipase A2, group XVI
Alias_symbol (synonym)HREV107
H-REV107-1
HREV107-3
MGC118754.
AdPLA
Other aliasH-REV107
HREV107-1
HRSL3
HGNC (Hugo) PLA2G16
LocusID (NCBI) 11145
Atlas_Id 40864
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 63574471 and ends at 63614469 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PLA2G16 (11q12.3) / PLA2G16 (11q12.3)SLC3A2 (11q12.3) / PLA2G16 (11q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLA2G16   17825
Cards
Entrez_Gene (NCBI)PLA2G16  11145  phospholipase A2 group XVI
AliasesAdPLA; H-REV107; H-REV107-1; HRASLS3; 
HREV107; HREV107-1; HREV107-3; HRSL3
GeneCards (Weizmann)PLA2G16
Ensembl hg19 (Hinxton)ENSG00000176485 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176485 [Gene_View]  chr11:63574471-63614469 [Contig_View]  PLA2G16 [Vega]
ICGC DataPortalENSG00000176485
TCGA cBioPortalPLA2G16
AceView (NCBI)PLA2G16
Genatlas (Paris)PLA2G16
WikiGenes11145
SOURCE (Princeton)PLA2G16
Genetics Home Reference (NIH)PLA2G16
Genomic and cartography
GoldenPath hg38 (UCSC)PLA2G16  -     chr11:63574471-63614469 -  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLA2G16  -     11q12.3   [Description]    (hg19-Feb_2009)
EnsemblPLA2G16 - 11q12.3 [CytoView hg19]  PLA2G16 - 11q12.3 [CytoView hg38]
Mapping of homologs : NCBIPLA2G16 [Mapview hg19]  PLA2G16 [Mapview hg38]
OMIM613867   
Gene and transcription
Genbank (Entrez)AB030814 AB439591 AF317086 AI374456 AI590735
RefSeq transcript (Entrez)NM_001128203 NM_007069
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLA2G16
Cluster EST : UnigeneHs.502775 [ NCBI ]
CGAP (NCI)Hs.502775
Alternative Splicing GalleryENSG00000176485
Gene ExpressionPLA2G16 [ NCBI-GEO ]   PLA2G16 [ EBI - ARRAY_EXPRESS ]   PLA2G16 [ SEEK ]   PLA2G16 [ MEM ]
Gene Expression Viewer (FireBrowse)PLA2G16 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11145
GTEX Portal (Tissue expression)PLA2G16
Protein : pattern, domain, 3D structure
UniProt/SwissProtP53816   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP53816  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP53816
Splice isoforms : SwissVarP53816
PhosPhoSitePlusP53816
Domains : Interpro (EBI)LRAT-like_dom   
Domain families : Pfam (Sanger)LRAT (PF04970)   
Domain families : Pfam (NCBI)pfam04970   
Conserved Domain (NCBI)PLA2G16
DMDM Disease mutations11145
Blocks (Seattle)PLA2G16
PDB (SRS)2KYT    4DOT    4FA0    4Q95   
PDB (PDBSum)2KYT    4DOT    4FA0    4Q95   
PDB (IMB)2KYT    4DOT    4FA0    4Q95   
PDB (RSDB)2KYT    4DOT    4FA0    4Q95   
Structural Biology KnowledgeBase2KYT    4DOT    4FA0    4Q95   
SCOP (Structural Classification of Proteins)2KYT    4DOT    4FA0    4Q95   
CATH (Classification of proteins structures)2KYT    4DOT    4FA0    4Q95   
SuperfamilyP53816
Human Protein AtlasENSG00000176485
Peptide AtlasP53816
HPRD13671
IPIIPI00296480   IPI01018155   IPI00654727   
Protein Interaction databases
DIP (DOE-UCLA)P53816
IntAct (EBI)P53816
FunCoupENSG00000176485
BioGRIDPLA2G16
STRING (EMBL)PLA2G16
ZODIACPLA2G16
Ontologies - Pathways
QuickGOP53816
Ontology : AmiGOphospholipase A2 activity  phospholipase A2 activity  protein binding  cellular_component  peroxisome  peroxisomal membrane  endoplasmic reticulum  cytosol  triglyceride metabolic process  phospholipid metabolic process  peroxisome organization  phospholipid biosynthetic process  phosphatidylcholine 1-acylhydrolase activity  integral component of membrane  lipid catabolic process  transferase activity, transferring acyl groups  phosphatidylinositol acyl-chain remodeling  phosphatidylserine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  negative regulation of cell cycle  ether lipid metabolic process  perinuclear region of cytoplasm  phosphatidylserine 1-acylhydrolase activity  1-acyl-2-lysophosphatidylserine acylhydrolase activity  regulation of adipose tissue development  
Ontology : EGO-EBIphospholipase A2 activity  phospholipase A2 activity  protein binding  cellular_component  peroxisome  peroxisomal membrane  endoplasmic reticulum  cytosol  triglyceride metabolic process  phospholipid metabolic process  peroxisome organization  phospholipid biosynthetic process  phosphatidylcholine 1-acylhydrolase activity  integral component of membrane  lipid catabolic process  transferase activity, transferring acyl groups  phosphatidylinositol acyl-chain remodeling  phosphatidylserine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  negative regulation of cell cycle  ether lipid metabolic process  perinuclear region of cytoplasm  phosphatidylserine 1-acylhydrolase activity  1-acyl-2-lysophosphatidylserine acylhydrolase activity  regulation of adipose tissue development  
Pathways : KEGGGlycerophospholipid metabolism    Ether lipid metabolism    Arachidonic acid metabolism    Linoleic acid metabolism    alpha-Linolenic acid metabolism    Ras signaling pathway   
NDEx NetworkPLA2G16
Atlas of Cancer Signalling NetworkPLA2G16
Wikipedia pathwaysPLA2G16
Orthology - Evolution
OrthoDB11145
GeneTree (enSembl)ENSG00000176485
Phylogenetic Trees/Animal Genes : TreeFamPLA2G16
HOVERGENP53816
HOGENOMP53816
Homologs : HomoloGenePLA2G16
Homology/Alignments : Family Browser (UCSC)PLA2G16
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLA2G16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLA2G16
dbVarPLA2G16
ClinVarPLA2G16
1000_GenomesPLA2G16 
Exome Variant ServerPLA2G16
ExAC (Exome Aggregation Consortium)PLA2G16 (select the gene name)
Genetic variants : HAPMAP11145
Genomic Variants (DGV)PLA2G16 [DGVbeta]
DECIPHERPLA2G16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLA2G16 
Mutations
ICGC Data PortalPLA2G16 
TCGA Data PortalPLA2G16 
Broad Tumor PortalPLA2G16
OASIS PortalPLA2G16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLA2G16  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPLA2G16
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PLA2G16
DgiDB (Drug Gene Interaction Database)PLA2G16
DoCM (Curated mutations)PLA2G16 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLA2G16 (select a term)
intoGenPLA2G16
Cancer3DPLA2G16(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613867   
Orphanet
MedgenPLA2G16
Genetic Testing Registry PLA2G16
NextProtP53816 [Medical]
TSGene11145
GENETestsPLA2G16
Huge Navigator PLA2G16 [HugePedia]
snp3D : Map Gene to Disease11145
BioCentury BCIQPLA2G16
ClinGenPLA2G16
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11145
Chemical/Pharm GKB GenePA164724584
Clinical trialPLA2G16
Miscellaneous
canSAR (ICR)PLA2G16 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLA2G16
EVEXPLA2G16
GoPubMedPLA2G16
iHOPPLA2G16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:31:27 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.