| Nomenclature |
HGNC (Hugo) | PLA2G2D 9033 |
| Cards |
Entrez_Gene (NCBI) | PLA2G2D 26279 phospholipase A2 group IID |
Aliases | PLA2IID; SPLASH; sPLA2-IID; sPLA2S |
GeneCards (Weizmann) | PLA2G2D |
Ensembl hg19 (Hinxton) | ENSG00000117215 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000117215 [Gene_View] chr1:20112650-20119566 [Contig_View] PLA2G2D [Vega] |
ICGC DataPortal | ENSG00000117215 |
TCGA cBioPortal | PLA2G2D |
AceView (NCBI) | PLA2G2D |
Genatlas (Paris) | PLA2G2D |
WikiGenes | 26279 |
SOURCE (Princeton) | PLA2G2D |
Genetics Home Reference (NIH) | PLA2G2D |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | PLA2G2D - chr1:20112650-20119566 - 1p36.12 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | PLA2G2D - 1p36.12 [Description] (hg19-Feb_2009) |
Ensembl | PLA2G2D - 1p36.12 [CytoView hg19] PLA2G2D - 1p36.12 [CytoView hg38] |
Mapping of homologs : NCBI | PLA2G2D [Mapview hg19] PLA2G2D [Mapview hg38] |
OMIM | 605630 |
| Gene and transcription |
Genbank (Entrez) | AF112982 AF188625 AK026347 AK290406 AK301396 |
RefSeq transcript (Entrez) | NM_001271814 NM_012400 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | PLA2G2D |
Cluster EST : Unigene | Hs.189507 [ NCBI ] |
CGAP (NCI) | Hs.189507 |
Alternative Splicing Gallery | ENSG00000117215 |
Gene Expression | PLA2G2D [ NCBI-GEO ] PLA2G2D [ EBI - ARRAY_EXPRESS ]
PLA2G2D [ SEEK ] PLA2G2D [ MEM ] |
Gene Expression Viewer (FireBrowse) | PLA2G2D [ Firebrowse - Broad ] |
SOURCE (Princeton) | Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60] |
Genevestigator | Expression in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 26279 |
GTEX Portal (Tissue expression) | PLA2G2D |
Human Protein Atlas | ENSG00000117215-PLA2G2D [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q9UNK4 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q9UNK4 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q9UNK4 |
Splice isoforms : SwissVar | Q9UNK4 |
Catalytic activity : Enzyme | 3.1.1.4 [ Enzyme-Expasy ] 3.1.1.43.1.1.4 [ IntEnz-EBI ] 3.1.1.4 [ BRENDA ] 3.1.1.4 [ KEGG ] |
PhosPhoSitePlus | Q9UNK4 |
Domaine pattern : Prosite (Expaxy) | PA2_ASP (PS00119) PA2_HIS (PS00118) |
Domains : Interpro (EBI) | PLipase_A2 PLipase_A2_Asp_AS PLipase_A2_dom PLipase_A2_His_AS |
Domain families : Pfam (Sanger) | Phospholip_A2_1 (PF00068) |
Domain families : Pfam (NCBI) | pfam00068 |
Domain families : Smart (EMBL) | PA2c (SM00085) |
Conserved Domain (NCBI) | PLA2G2D |
DMDM Disease mutations | 26279 |
Blocks (Seattle) | PLA2G2D |
Superfamily | Q9UNK4 |
Human Protein Atlas [tissue] | ENSG00000117215-PLA2G2D [tissue] |
Peptide Atlas | Q9UNK4 |
HPRD | 07546 |
IPI | IPI00018259 IPI00432402 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q9UNK4 |
IntAct (EBI) | Q9UNK4 |
FunCoup | ENSG00000117215 |
BioGRID | PLA2G2D |
STRING (EMBL) | PLA2G2D |
ZODIAC | PLA2G2D |
| Ontologies - Pathways |
QuickGO | Q9UNK4 |
Ontology : AmiGO | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation phospholipase A2 activity calcium ion binding extracellular region phospholipid metabolic process phosphatidic acid biosynthetic process inflammatory response heparin binding lipid catabolic process phosphatidylglycerol acyl-chain remodeling phosphatidylinositol acyl-chain remodeling phosphatidylserine acyl-chain remodeling phosphatidylcholine acyl-chain remodeling phosphatidylethanolamine acyl-chain remodeling negative regulation of T cell proliferation heparan sulfate proteoglycan binding arachidonic acid secretion phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) |
Ontology : EGO-EBI | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation phospholipase A2 activity calcium ion binding extracellular region phospholipid metabolic process phosphatidic acid biosynthetic process inflammatory response heparin binding lipid catabolic process phosphatidylglycerol acyl-chain remodeling phosphatidylinositol acyl-chain remodeling phosphatidylserine acyl-chain remodeling phosphatidylcholine acyl-chain remodeling phosphatidylethanolamine acyl-chain remodeling negative regulation of T cell proliferation heparan sulfate proteoglycan binding arachidonic acid secretion phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) |
Pathways : KEGG | Long-term depression VEGF signaling pathway Glycerophospholipid metabolism MAPK signaling pathway GnRH signaling pathway Linoleic acid metabolism Arachidonic acid metabolism Fc epsilon RI signaling pathway |
NDEx Network | PLA2G2D |
Atlas of Cancer Signalling Network | PLA2G2D |
Wikipedia pathways | PLA2G2D |
| Orthology - Evolution |
OrthoDB | 26279 |
GeneTree (enSembl) | ENSG00000117215 |
Phylogenetic Trees/Animal Genes : TreeFam | PLA2G2D |
HOVERGEN | Q9UNK4 |
HOGENOM | Q9UNK4 |
Homologs : HomoloGene | PLA2G2D |
Homology/Alignments : Family Browser (UCSC) | PLA2G2D |
| Gene fusions - Rearrangements |
Fusion : Quiver | PLA2G2D |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | PLA2G2D [hg38] |
dbSNP Single Nucleotide Polymorphism (NCBI) | PLA2G2D |
dbVar | PLA2G2D |
ClinVar | PLA2G2D |
1000_Genomes | PLA2G2D |
Exome Variant Server | PLA2G2D |
ExAC (Exome Aggregation Consortium) | ENSG00000117215 |
GNOMAD Browser | ENSG00000117215 |
Genetic variants : HAPMAP | 26279 |
Genomic Variants (DGV) | PLA2G2D [DGVbeta] |
DECIPHER | PLA2G2D [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | PLA2G2D |
| Mutations |
ICGC Data Portal | PLA2G2D |
TCGA Data Portal | PLA2G2D |
Broad Tumor Portal | PLA2G2D |
OASIS Portal | PLA2G2D [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | PLA2G2D [overview] [genome browser] [tissue] [distribution] |
Mutations and Diseases : HGMD | PLA2G2D |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search PLA2G2D |
DgiDB (Drug Gene Interaction Database) | PLA2G2D |
DoCM (Curated mutations) | PLA2G2D (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | PLA2G2D (select a term) |
intoGen | PLA2G2D |
Cancer3D | PLA2G2D(select the gene name) |
Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 605630 |
Orphanet | |
DisGeNET | PLA2G2D |
Medgen | PLA2G2D |
Genetic Testing Registry | PLA2G2D
|
NextProt | Q9UNK4 [Medical] |
TSGene | 26279 |
GENETests | PLA2G2D |
Target Validation | PLA2G2D |
Huge Navigator |
PLA2G2D [HugePedia] |
snp3D : Map Gene to Disease | 26279 |
BioCentury BCIQ | PLA2G2D |
ClinGen | PLA2G2D |
| Clinical trials, drugs, therapy |
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Chemical/Protein Interactions : CTD | 26279 |
Chemical/Pharm GKB Gene | PA33363 |
Clinical trial | PLA2G2D |
| Miscellaneous |
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canSAR (ICR) | PLA2G2D (select the gene name) |
| Probes |
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| Litterature |
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PubMed | 28 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | PLA2G2D |
EVEX | PLA2G2D |
GoPubMed | PLA2G2D |
iHOP | PLA2G2D |