PLA2G3 (phospholipase A2, group III)

Identity

Other names	GIII-SPLA2
	SPLA2III
HGNC	PLA2G3
Location	22q12.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PLA2G3   17934
Entrez_Gene	PLA2G3  50487  phospholipase A2, group III
	Cards
GeneCards	PLA2G3
Ensembl	PLA2G3 [Search_View]   ENSG00000100078 [Gene_View]
Genatlas	PLA2G3
GeneLynx	PLA2G3
eGenome	PLA2G3
euGene	50487
	Genomic and cartography
GoldenPath	PLA2G3  -  22q12.2   chr22:29860793-29866469 -  22q12.2   [Description]    (hg18-March_2006)
Ensembl	PLA2G3 - 22q12.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PLA2G3
	Gene and transcription
Genbank	AF220490 [ ENTREZ ]
Genbank	BC025316 [ ENTREZ ]
Genbank	DQ892832 [ ENTREZ ]
Genbank	DQ896078 [ ENTREZ ]
RefSeq	NM_015715 [ SRS ]    NM_015715 [ ENTREZ ]
RefSeq	AC_000065 [ SRS ]    AC_000065 [ ENTREZ ]
RefSeq	AC_000154 [ SRS ]    AC_000154 [ ENTREZ ]
RefSeq	NC_000022 [ SRS ]    NC_000022 [ ENTREZ ]
RefSeq	NT_011520 [ SRS ]    NT_011520 [ ENTREZ ]
RefSeq	NW_001838745 [ SRS ]    NW_001838745 [ ENTREZ ]
RefSeq	NW_927628 [ SRS ]    NW_927628 [ ENTREZ ]
AceView	PLA2G3 AceView - NCBI
Unigene	Hs.149623 [ SRS ]    Hs.149623 [ NCBI ]     HS149623 [ spliceNest ]
Fast-db	4520 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9NZ20 [ SRS]    Q9NZ20 [ EXPASY ]     Q9NZ20 [ INTERPRO ]     Q9NZ20 [ UNIPROT ]
Prosite	PS00119 PA2_ASP [ SRS ]    PS00119 PA2_ASP [ Expasy ]
Prosite	PS00118 PA2_HIS [ SRS ]    PS00118 PA2_HIS [ Expasy ]
Interpro	IPR016090 Phospholipase_A2 [ SRS ]    IPR016090 Phospholipase_A2 [ EBI ]
Interpro	IPR013090 Phospholipase_A2_AS [ SRS ]    IPR013090 Phospholipase_A2_AS [ EBI ]
Interpro	IPR001211 Phospholipase_A2_euk [ SRS ]    IPR001211 Phospholipase_A2_euk [ EBI ]
Interpro	IPR008774 Phospholipase_A2_met [ SRS ]    IPR008774 Phospholipase_A2_met [ EBI ]
CluSTr	Q9NZ20
Pfam	PF05826 Phospholip_A2_2 [ SRS ]    PF05826 Phospholip_A2_2 [ Sanger ]    pfam05826 [ NCBI-CDD ]
Smart	SM00085 PA2c [EMBL]
Blocks	Q9NZ20
HPRD	07144
	Protein Interaction databases
DIP	Q9NZ20
IntAct	Q9NZ20
	Polymorphism : SNP, mutations, diseases
OMIM	611651    [ map ]
GENECLINICS	611651
SNP	PLA2G3 [dbSNP-NCBI]
SNP	NM_015715 [SNP-NCI]
SNP	PLA2G3 [GeneSNPs - Utah]  PLA2G3] [HGBASE - SRS]
HAPMAP	PLA2G3 [HAPMAP]
COSMIC	PLA2G3 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PLA2G3
	General knowledge
Family Browser	PLA2G3 [UCSC Family Browser]
SOURCE	NM_015715
SMD	Hs.149623
SAGE	Hs.149623
Enzyme	3.1.1.4 [ Enzyme-Expasy ]   3.1.1.4 [ Enzyme-SRS ]   3.1.1.4 [ IntEnz-EBI ]   3.1.1.4 [ BRENDA ]   3.1.1.4 [ KEGG ]   3.1.1.4 [ WIT ]
GO	calcium ion binding [Amigo]  calcium ion binding
GO	extracellular region [Amigo]  extracellular region
GO	extracellular space [Amigo]  extracellular space
GO	plasma membrane [Amigo]  plasma membrane
GO	phospholipid metabolic process [Amigo]  phospholipid metabolic process
GO	lipid catabolic process [Amigo]  lipid catabolic process
GO	hydrolase activity [Amigo]  hydrolase activity
GO	calcium-dependent phospholipase A2 activity [Amigo]  calcium-dependent phospholipase A2 activity
KEGG	Glycerophospholipid metabolism
KEGG	Arachidonic acid metabolism
KEGG	Linoleic acid metabolism
KEGG	MAPK signaling pathway
KEGG	VEGF signaling pathway
KEGG	Fc epsilon RI signaling pathway
KEGG	Long-term depression
KEGG	GnRH signaling pathway
PubGene	PLA2G3
TreeFam	PLA2G3
CTD	50487 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PLA2G3 Related clones (RZPD - Berlin)
	PubMed
PubMed	11 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:25:09 2008