Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PLA2G4C (phospholipase A2, group IVC (cytosolic, calcium-independent))

Identity

Other namesCPLA2-gamma
HGNC (Hugo) PLA2G4C
LocusID (NCBI) 8605
Location 19q13.33
Location_base_pair Starts at 48551100 and ends at 48614109 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PLA2G4C   9037
Entrez_Gene (NCBI)PLA2G4C  8605  phospholipase A2, group IVC (cytosolic, calcium-independent)
Cards
GeneCards (Weizmann)PLA2G4C
Ensembl (Hinxton)ENSG00000105499 [Gene_View]  chr19:48551100-48614109 [Contig_View]  PLA2G4C [Vega]
AceView (NCBI)PLA2G4C
Genatlas (Paris)PLA2G4C
SOURCE (Stanford)NM_001159322 NM_001159323 NM_003706
Genomic and cartography
GoldenPath (UCSC)PLA2G4C  -  19q13.33   chr19:48551100-48614109 -  19q13.33   [Description]    (hg19-Feb_2009)
EnsemblPLA2G4C - 19q13.33 [CytoView]
Mapping of homologs : NCBIPLA2G4C [Mapview]
OMIM603602   
Gene and transcription
Genbank (Entrez)AF058921 AF065214 AK022440 AK124241 AK126152
RefSeq transcript (SRS)NM_001159322 NM_001159323 NM_003706
RefSeq transcript (Entrez)NM_001159322 NM_001159323 NM_003706
RefSeq genomic (SRS)AC_000151 NC_000019 NC_018930 NG_016021 NT_011109 NW_001838497 NW_004078099
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NG_016021 NT_011109 NW_001838497 NW_004078099
Consensus coding sequences : CCDS (NCBI)PLA2G4C
Cluster EST : UnigeneHs.631562 [ SRS ] Hs.631562 [ NCBI ]
CGAP (NCI)Hs.631562
Alternative Splicing : Fast-db (Paris)GSHG0015961
Alternative Splicing GalleryENSG00000105499
Gene ExpressionPLA2G4C [ NCBI-GEO ]   PLA2G4C [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UP65 (SRS) Q9UP65 (Uniprot)
NextProtQ9UP65
With graphics : InterProQ9UP65
Splice isoforms : SwissVarQ9UP65(Swissvar)
Domaine pattern : Prosite (SRS)PLA2C (PS51210)   
Domaine pattern : Prosite (Expaxy)PLA2C (PS51210)   
Domains : Interpro (SRS)Acyl_Trfase/lysoPLipase    LysoPLipase_cat_dom   
Domains : Interpro (EBI)Acyl_Trfase/lysoPLipase    LysoPLipase_cat_dom   
Related proteins : CluSTrQ9UP65
Domain families : Pfam (SRS)PLA2_B (PF01735)   
Domain families : Pfam (Sanger)PLA2_B (PF01735)   
Domain families : Pfam (NCBI)pfam01735   
Domain families : Smart (EMBL)PLAc (SM00022)  
DMDM8605
Blocks (Seattle)Q9UP65
Human Protein AtlasENSG00000105499
HPRD04673
IPIIPI00910091   IPI00929100   IPI00929453   
Protein Interaction databases
DIP (DOE-UCLA)Q9UP65
IntAct (EBI)Q9UP65
FunCoupENSG00000105499
REACTOMEPLA2G4C
Protein Interaction Database8605
BioGRIDPLA2G4C
InParanoidQ9UP65
Interologous Interaction database Q9UP65
IntegromeDBPLA2G4C
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PLA2G4C
SNP (GeneSNP Utah)PLA2G4C
SNP : HGBasePLA2G4C
Genetic variants : HAPMAPPLA2G4C
Somatic Mutations in Cancer : COSMICPLA2G4C 
CONAN: Copy Number AnalysisPLA2G4C 
Mutations and Diseases : HGMDPLA2G4C
OMIM603602   
GENETests603602   
Disease Genetic AssociationPLA2G4C
Huge Navigator PLA2G4C [HugePedia]  PLA2G4C [HugeCancerGEM]
Genomic VariantsPLA2G4C  PLA2G4C [DGVbeta]
ClinVarPLA2G4C
snp3D : Map Gene to Disease8605
General knowledge
Homologs : HomoloGenePLA2G4C
Homology/Alignments : Family Browser (UCSC)PLA2G4C
Phylogenetic Trees/Animal Genes : TreeFamPLA2G4C
Catalytic activity : Enzyme3.1.1.4 [ Enzyme-Expasy ]   3.1.1.4 [ Enzyme-SRS ]   3.1.1.4 [ IntEnz-EBI ]   3.1.1.4 [ BRENDA ]   3.1.1.4 [ KEGG ]   
Chemical/Protein Interactions : CTD8605
Chemical/Pharm GKB GenePA33365
Clinical trialPLA2G4C
Cancer Resource (Charite)ENSG00000105499
Ontology : AmiGOphospholipid binding  endoplasmic reticulum membrane  cytosol  phospholipid metabolic process  inflammatory response  parturition  membrane  arachidonic acid metabolic process  intracellular signal transduction  phosphatidylinositol acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  small molecule metabolic process  glycerophospholipid biosynthetic process  glycerophospholipid catabolic process  calcium-independent phospholipase A2 activity  
Ontology : EGO-EBIphospholipid binding  endoplasmic reticulum membrane  cytosol  phospholipid metabolic process  inflammatory response  parturition  membrane  arachidonic acid metabolic process  intracellular signal transduction  phosphatidylinositol acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  small molecule metabolic process  glycerophospholipid biosynthetic process  glycerophospholipid catabolic process  calcium-independent phospholipase A2 activity  
Other databases
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
PubGenePLA2G4C
iHOPPLA2G4C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:34:27 CEST 2013
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.