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PLA2G4D (phospholipase A2, group IVD (cytosolic))

Identity

Alias_namesphospholipase A2, group IVD (cytosolic)
Alias_symbol (synonym)cPLA2delta
Other alias
HGNC (Hugo) PLA2G4D
LocusID (NCBI) 283748
Atlas_Id 71955
Location 15q15.1  [Link to chromosome band 15q15]
Location_base_pair Starts at 42359881 and ends at 42386752 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLA2G4D   30038
Cards
Entrez_Gene (NCBI)PLA2G4D  283748  phospholipase A2, group IVD (cytosolic)
AliasescPLA2delta
GeneCards (Weizmann)PLA2G4D
Ensembl hg19 (Hinxton)ENSG00000159337 [Gene_View]  chr15:42359881-42386752 [Contig_View]  PLA2G4D [Vega]
Ensembl hg38 (Hinxton)ENSG00000159337 [Gene_View]  chr15:42359881-42386752 [Contig_View]  PLA2G4D [Vega]
ICGC DataPortalENSG00000159337
TCGA cBioPortalPLA2G4D
AceView (NCBI)PLA2G4D
Genatlas (Paris)PLA2G4D
WikiGenes283748
SOURCE (Princeton)PLA2G4D
Genetics Home Reference (NIH)PLA2G4D
Genomic and cartography
GoldenPath hg19 (UCSC)PLA2G4D  -     chr15:42359881-42386752 -  15q15.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PLA2G4D  -     15q15.1   [Description]    (hg38-Dec_2013)
EnsemblPLA2G4D - 15q15.1 [CytoView hg19]  PLA2G4D - 15q15.1 [CytoView hg38]
Mapping of homologs : NCBIPLA2G4D [Mapview hg19]  PLA2G4D [Mapview hg38]
OMIM612864   
Gene and transcription
Genbank (Entrez)AB090876 BC034571 BC140416 BC146533 DQ891792
RefSeq transcript (Entrez)NM_178034
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)PLA2G4D
Cluster EST : UnigeneHs.380225 [ NCBI ]
CGAP (NCI)Hs.380225
Alternative Splicing GalleryENSG00000159337
Gene ExpressionPLA2G4D [ NCBI-GEO ]   PLA2G4D [ EBI - ARRAY_EXPRESS ]   PLA2G4D [ SEEK ]   PLA2G4D [ MEM ]
Gene Expression Viewer (FireBrowse)PLA2G4D [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)283748
GTEX Portal (Tissue expression)PLA2G4D
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86XP0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86XP0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86XP0
Splice isoforms : SwissVarQ86XP0
Catalytic activity : Enzyme3.1.1.4 [ Enzyme-Expasy ]   3.1.1.43.1.1.4 [ IntEnz-EBI ]   3.1.1.4 [ BRENDA ]   3.1.1.4 [ KEGG ]   
PhosPhoSitePlusQ86XP0
Domaine pattern : Prosite (Expaxy)C2 (PS50004)    PLA2C (PS51210)   
Domains : Interpro (EBI)Acyl_Trfase/lysoPLipase    C2_dom    LysoPLipase_cat_dom   
Domain families : Pfam (Sanger)C2 (PF00168)    PLA2_B (PF01735)   
Domain families : Pfam (NCBI)pfam00168    pfam01735   
Domain families : Smart (EMBL)C2 (SM00239)  PLAc (SM00022)  
Conserved Domain (NCBI)PLA2G4D
DMDM Disease mutations283748
Blocks (Seattle)PLA2G4D
SuperfamilyQ86XP0
Human Protein AtlasENSG00000159337
Peptide AtlasQ86XP0
HPRD07145
IPIIPI00384577   IPI00784249   
Protein Interaction databases
DIP (DOE-UCLA)Q86XP0
IntAct (EBI)Q86XP0
FunCoupENSG00000159337
BioGRIDPLA2G4D
STRING (EMBL)PLA2G4D
ZODIACPLA2G4D
Ontologies - Pathways
QuickGOQ86XP0
Ontology : AmiGOphospholipase A2 activity  cytosol  phospholipid metabolic process  phosphatidic acid biosynthetic process  phospholipid catabolic process  cytoplasmic vesicle membrane  phosphatidylglycerol acyl-chain remodeling  phosphatidylinositol acyl-chain remodeling  phosphatidylserine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  small molecule metabolic process  glycerophospholipid biosynthetic process  metal ion binding  
Ontology : EGO-EBIphospholipase A2 activity  cytosol  phospholipid metabolic process  phosphatidic acid biosynthetic process  phospholipid catabolic process  cytoplasmic vesicle membrane  phosphatidylglycerol acyl-chain remodeling  phosphatidylinositol acyl-chain remodeling  phosphatidylserine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  small molecule metabolic process  glycerophospholipid biosynthetic process  metal ion binding  
Pathways : KEGGGlycerophospholipid metabolism    Ether lipid metabolism    Arachidonic acid metabolism    Linoleic acid metabolism    alpha-Linolenic acid metabolism    MAPK signaling pathway    Ras signaling pathway    Vascular smooth muscle contraction    VEGF signaling pathway    Fc epsilon RI signaling pathway    Fc gamma R-mediated phagocytosis    Glutamatergic synapse    Serotonergic synapse    Long-term depression    GnRH signaling pathway    Ovarian steroidogenesis   
NDEx NetworkPLA2G4D
Atlas of Cancer Signalling NetworkPLA2G4D
Wikipedia pathwaysPLA2G4D
Orthology - Evolution
OrthoDB283748
GeneTree (enSembl)ENSG00000159337
Phylogenetic Trees/Animal Genes : TreeFamPLA2G4D
HOVERGENQ86XP0
HOGENOMQ86XP0
Homologs : HomoloGenePLA2G4D
Homology/Alignments : Family Browser (UCSC)PLA2G4D
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLA2G4D [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLA2G4D
dbVarPLA2G4D
ClinVarPLA2G4D
1000_GenomesPLA2G4D 
Exome Variant ServerPLA2G4D
ExAC (Exome Aggregation Consortium)PLA2G4D (select the gene name)
Genetic variants : HAPMAP283748
Genomic Variants (DGV)PLA2G4D [DGVbeta]
DECIPHER (Syndromes)15:42359881-42386752  ENSG00000159337
CONAN: Copy Number AnalysisPLA2G4D 
Mutations
ICGC Data PortalPLA2G4D 
TCGA Data PortalPLA2G4D 
Broad Tumor PortalPLA2G4D
OASIS PortalPLA2G4D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLA2G4D  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPLA2G4D
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PLA2G4D
DgiDB (Drug Gene Interaction Database)PLA2G4D
DoCM (Curated mutations)PLA2G4D (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLA2G4D (select a term)
intoGenPLA2G4D
Cancer3DPLA2G4D(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612864   
Orphanet
MedgenPLA2G4D
Genetic Testing Registry PLA2G4D
NextProtQ86XP0 [Medical]
TSGene283748
GENETestsPLA2G4D
Huge Navigator PLA2G4D [HugePedia]
snp3D : Map Gene to Disease283748
BioCentury BCIQPLA2G4D
ClinGenPLA2G4D
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD283748
Chemical/Pharm GKB GenePA134974074
Clinical trialPLA2G4D
Miscellaneous
canSAR (ICR)PLA2G4D (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLA2G4D
EVEXPLA2G4D
GoPubMedPLA2G4D
iHOPPLA2G4D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:38:48 CET 2017

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