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PLA2G4F (phospholipase A2 group IVF)

Identity

Alias_namesphospholipase A2, group IVF
Alias_symbol (synonym)PLA2G4F/Z
Other aliasPLA2G4FZ
HGNC (Hugo) PLA2G4F
LocusID (NCBI) 255189
Atlas_Id 71957
Location 15q15.1  [Link to chromosome band 15q15]
Location_base_pair Starts at 42141134 and ends at 42156641 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLA2G4F   27396
Cards
Entrez_Gene (NCBI)PLA2G4F  255189  phospholipase A2 group IVF
AliasesPLA2G4FZ
GeneCards (Weizmann)PLA2G4F
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr15:42141134-42156641 [Contig_View]  PLA2G4F [Vega]
TCGA cBioPortalPLA2G4F
AceView (NCBI)PLA2G4F
Genatlas (Paris)PLA2G4F
WikiGenes255189
SOURCE (Princeton)PLA2G4F
Genetics Home Reference (NIH)PLA2G4F
Genomic and cartography
GoldenPath hg38 (UCSC)PLA2G4F  -     chr15:42141134-42156641 -  15q15.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLA2G4F  -     15q15.1   [Description]    (hg19-Feb_2009)
EnsemblPLA2G4F - 15q15.1 [CytoView hg19]  PLA2G4F - 15q15.1 [CytoView hg38]
Mapping of homologs : NCBIPLA2G4F [Mapview hg19]  PLA2G4F [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK122623 AK172836 AK304368 AL832972 BC035335
RefSeq transcript (Entrez)NM_213600
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLA2G4F
Cluster EST : UnigeneHs.231873 [ NCBI ]
CGAP (NCI)Hs.231873
Gene ExpressionPLA2G4F [ NCBI-GEO ]   PLA2G4F [ EBI - ARRAY_EXPRESS ]   PLA2G4F [ SEEK ]   PLA2G4F [ MEM ]
Gene Expression Viewer (FireBrowse)PLA2G4F [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)255189
GTEX Portal (Tissue expression)PLA2G4F
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ68DD2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ68DD2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ68DD2
Splice isoforms : SwissVarQ68DD2
Catalytic activity : Enzyme3.1.1.4 [ Enzyme-Expasy ]   3.1.1.43.1.1.4 [ IntEnz-EBI ]   3.1.1.4 [ BRENDA ]   3.1.1.4 [ KEGG ]   
PhosPhoSitePlusQ68DD2
Domaine pattern : Prosite (Expaxy)C2 (PS50004)    PLA2C (PS51210)   
Domains : Interpro (EBI)Acyl_Trfase/lysoPLipase    C2_dom    LysoPLipase_cat_dom   
Domain families : Pfam (Sanger)C2 (PF00168)    PLA2_B (PF01735)   
Domain families : Pfam (NCBI)pfam00168    pfam01735   
Domain families : Smart (EMBL)C2 (SM00239)  PLAc (SM00022)  
Conserved Domain (NCBI)PLA2G4F
DMDM Disease mutations255189
Blocks (Seattle)PLA2G4F
SuperfamilyQ68DD2
Peptide AtlasQ68DD2
HPRD17326
IPIIPI00940945   IPI00783797   IPI00216800   IPI00743154   IPI00952966   IPI00477968   
Protein Interaction databases
DIP (DOE-UCLA)Q68DD2
IntAct (EBI)Q68DD2
BioGRIDPLA2G4F
STRING (EMBL)PLA2G4F
ZODIACPLA2G4F
Ontologies - Pathways
QuickGOQ68DD2
Ontology : AmiGOprostaglandin biosynthetic process  lysophospholipase activity  phospholipase A2 activity  lysosome  lysosomal membrane  cytosol  phospholipid metabolic process  phosphatidylcholine 1-acylhydrolase activity  phospholipid catabolic process  vesicle  ruffle membrane  phosphatidylglycerol acyl-chain remodeling  phosphatidylinositol acyl-chain remodeling  phosphatidylserine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  metal ion binding  calcium-dependent phospholipase A2 activity  arachidonic acid secretion  cellular response to antibiotic  cellular response to organic cyclic compound  
Ontology : EGO-EBIprostaglandin biosynthetic process  lysophospholipase activity  phospholipase A2 activity  lysosome  lysosomal membrane  cytosol  phospholipid metabolic process  phosphatidylcholine 1-acylhydrolase activity  phospholipid catabolic process  vesicle  ruffle membrane  phosphatidylglycerol acyl-chain remodeling  phosphatidylinositol acyl-chain remodeling  phosphatidylserine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  metal ion binding  calcium-dependent phospholipase A2 activity  arachidonic acid secretion  cellular response to antibiotic  cellular response to organic cyclic compound  
Pathways : KEGGGlycerophospholipid metabolism    Ether lipid metabolism    Arachidonic acid metabolism    Linoleic acid metabolism    alpha-Linolenic acid metabolism    MAPK signaling pathway    Ras signaling pathway    Vascular smooth muscle contraction    VEGF signaling pathway    Fc epsilon RI signaling pathway    Fc gamma R-mediated phagocytosis    Glutamatergic synapse    Serotonergic synapse    Long-term depression    GnRH signaling pathway    Ovarian steroidogenesis   
NDEx NetworkPLA2G4F
Atlas of Cancer Signalling NetworkPLA2G4F
Wikipedia pathwaysPLA2G4F
Orthology - Evolution
OrthoDB255189
Phylogenetic Trees/Animal Genes : TreeFamPLA2G4F
HOVERGENQ68DD2
HOGENOMQ68DD2
Homologs : HomoloGenePLA2G4F
Homology/Alignments : Family Browser (UCSC)PLA2G4F
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLA2G4F [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLA2G4F
dbVarPLA2G4F
ClinVarPLA2G4F
1000_GenomesPLA2G4F 
Exome Variant ServerPLA2G4F
ExAC (Exome Aggregation Consortium)PLA2G4F (select the gene name)
Genetic variants : HAPMAP255189
Genomic Variants (DGV)PLA2G4F [DGVbeta]
DECIPHERPLA2G4F [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLA2G4F 
Mutations
ICGC Data PortalPLA2G4F 
TCGA Data PortalPLA2G4F 
Broad Tumor PortalPLA2G4F
OASIS PortalPLA2G4F [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLA2G4F  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPLA2G4F
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PLA2G4F
DgiDB (Drug Gene Interaction Database)PLA2G4F
DoCM (Curated mutations)PLA2G4F (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLA2G4F (select a term)
intoGenPLA2G4F
Cancer3DPLA2G4F(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPLA2G4F
Genetic Testing Registry PLA2G4F
NextProtQ68DD2 [Medical]
TSGene255189
GENETestsPLA2G4F
Target ValidationPLA2G4F
Huge Navigator PLA2G4F [HugePedia]
snp3D : Map Gene to Disease255189
BioCentury BCIQPLA2G4F
ClinGenPLA2G4F
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD255189
Chemical/Pharm GKB GenePA142671170
Clinical trialPLA2G4F
Miscellaneous
canSAR (ICR)PLA2G4F (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLA2G4F
EVEXPLA2G4F
GoPubMedPLA2G4F
iHOPPLA2G4F
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:36:31 CEST 2017

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