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PLAAT2 (phospholipase A and acyltransferase 2)

Identity

Alias_namesHRASLS2
HRAS like suppressor 2
Alias_symbol (synonym)FLJ20556
PLAAT-2
Other aliasPLA1/2-2
HGNC (Hugo) PLAAT2
LocusID (NCBI) 54979
Atlas_Id 50352
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 63552770 and ends at 63563383 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)PLAAT2   17824
Cards
Entrez_Gene (NCBI)PLAAT2  54979  phospholipase A and acyltransferase 2
AliasesHRASLS2; PLA1/2-2; PLAAT-2
GeneCards (Weizmann)PLAAT2
Ensembl hg19 (Hinxton)ENSG00000133328 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000133328 [Gene_View]  ENSG00000133328 [Sequence]  chr11:63552770-63563383 [Contig_View]  PLAAT2 [Vega]
ICGC DataPortalENSG00000133328
TCGA cBioPortalPLAAT2
AceView (NCBI)PLAAT2
Genatlas (Paris)PLAAT2
WikiGenes54979
SOURCE (Princeton)PLAAT2
Genetics Home Reference (NIH)PLAAT2
Genomic and cartography
GoldenPath hg38 (UCSC)PLAAT2  -     chr11:63552770-63563383 -  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLAAT2  -     -   [Description]    (hg19-Feb_2009)
GoldenPathPLAAT2 - - [CytoView hg19]  PLAAT2 - - [CytoView hg38]
ImmunoBaseENSG00000133328
Mapping of homologs : NCBIPLAAT2 [Mapview hg19]  PLAAT2 [Mapview hg38]
OMIM613866   
Gene and transcription
Genbank (Entrez)AB453251 AK000563
RefSeq transcript (Entrez)NM_017878
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLAAT2
Cluster EST : UnigeneHs.272805 [ NCBI ]
CGAP (NCI)Hs.272805
Alternative Splicing GalleryENSG00000133328
Gene ExpressionPLAAT2 [ NCBI-GEO ]   PLAAT2 [ EBI - ARRAY_EXPRESS ]   PLAAT2 [ SEEK ]   PLAAT2 [ MEM ]
Gene Expression Viewer (FireBrowse)PLAAT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54979
GTEX Portal (Tissue expression)PLAAT2
Human Protein AtlasENSG00000133328-PLAAT2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NWW9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NWW9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NWW9
Splice isoforms : SwissVarQ9NWW9
PhosPhoSitePlusQ9NWW9
Domains : Interpro (EBI)LRAT-like_dom   
Domain families : Pfam (Sanger)LRAT (PF04970)   
Domain families : Pfam (NCBI)pfam04970   
Conserved Domain (NCBI)PLAAT2
DMDM Disease mutations54979
Blocks (Seattle)PLAAT2
PDB (RSDB)4DPZ   
PDB Europe4DPZ   
PDB (PDBSum)4DPZ   
PDB (IMB)4DPZ   
Structural Biology KnowledgeBase4DPZ   
SCOP (Structural Classification of Proteins)4DPZ   
CATH (Classification of proteins structures)4DPZ   
SuperfamilyQ9NWW9
Human Protein Atlas [tissue]ENSG00000133328-PLAAT2 [tissue]
Peptide AtlasQ9NWW9
HPRD13670
IPIIPI00016569   
Protein Interaction databases
DIP (DOE-UCLA)Q9NWW9
IntAct (EBI)Q9NWW9
FunCoupENSG00000133328
BioGRIDPLAAT2
STRING (EMBL)PLAAT2
ZODIACPLAAT2
Ontologies - Pathways
QuickGOQ9NWW9
Ontology : AmiGOphospholipase A2 activity  cytosol  phospholipase A1 activity  integral component of membrane  lipid catabolic process  N-acyltransferase activity  phosphatidylethanolamine acyl-chain remodeling  phosphatidylserine 1-acylhydrolase activity  1-acyl-2-lysophosphatidylserine acylhydrolase activity  N-acylphosphatidylethanolamine metabolic process  phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)  phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)  
Ontology : EGO-EBIphospholipase A2 activity  cytosol  phospholipase A1 activity  integral component of membrane  lipid catabolic process  N-acyltransferase activity  phosphatidylethanolamine acyl-chain remodeling  phosphatidylserine 1-acylhydrolase activity  1-acyl-2-lysophosphatidylserine acylhydrolase activity  N-acylphosphatidylethanolamine metabolic process  phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)  phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)  
NDEx NetworkPLAAT2
Atlas of Cancer Signalling NetworkPLAAT2
Wikipedia pathwaysPLAAT2
Orthology - Evolution
OrthoDB54979
GeneTree (enSembl)ENSG00000133328
Phylogenetic Trees/Animal Genes : TreeFamPLAAT2
HOGENOMQ9NWW9
Homologs : HomoloGenePLAAT2
Homology/Alignments : Family Browser (UCSC)PLAAT2
Gene fusions - Rearrangements
Fusion : QuiverPLAAT2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLAAT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLAAT2
dbVarPLAAT2
ClinVarPLAAT2
1000_GenomesPLAAT2 
Exome Variant ServerPLAAT2
ExAC (Exome Aggregation Consortium)ENSG00000133328
GNOMAD BrowserENSG00000133328
Varsome BrowserPLAAT2
Genetic variants : HAPMAP54979
Genomic Variants (DGV)PLAAT2 [DGVbeta]
DECIPHERPLAAT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLAAT2 
Mutations
ICGC Data PortalPLAAT2 
TCGA Data PortalPLAAT2 
Broad Tumor PortalPLAAT2
OASIS PortalPLAAT2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPLAAT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PLAAT2
DgiDB (Drug Gene Interaction Database)PLAAT2
DoCM (Curated mutations)PLAAT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLAAT2 (select a term)
intoGenPLAAT2
Cancer3DPLAAT2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613866   
Orphanet
DisGeNETPLAAT2
MedgenPLAAT2
Genetic Testing Registry PLAAT2
NextProtQ9NWW9 [Medical]
TSGene54979
GENETestsPLAAT2
Target ValidationPLAAT2
Huge Navigator PLAAT2 [HugePedia]
snp3D : Map Gene to Disease54979
BioCentury BCIQPLAAT2
ClinGenPLAAT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54979
Chemical/Pharm GKB GenePA29446
Clinical trialPLAAT2
Miscellaneous
canSAR (ICR)PLAAT2 (select the gene name)
DataMed IndexPLAAT2
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLAAT2
EVEXPLAAT2
GoPubMedPLAAT2
iHOPPLAAT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 26 18:23:27 CEST 2019

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