PLAAT3 (phospholipase A and acyltransferase 3)

2003-02-01  

Identity

HGNC
PLAAT3
LOCATION
11q12.3
LOCUSID
11145
ALIAS
AdPLA,H-REV107,H-REV107-1,HRASLS3,HREV107,HREV107-1,HREV107-3,HRSL3,PLA2G16,PLAAT-3

Other Information

Locus ID:

NCBI: 11145
MIM: 613867
HGNC: 17825
Ensembl: ENSG00000176485

Variants:

dbSNP: 11145
ClinVar: 11145
TCGA: ENSG00000176485
COSMIC: PLAAT3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176485ENST00000323646P53816
ENSG00000176485ENST00000323646A0A024R561
ENSG00000176485ENST00000415826P53816
ENSG00000176485ENST00000415826A0A024R561
ENSG00000176485ENST00000540943F5H7E5
ENSG00000176485ENST00000639271A0A1W2PRW4

Pathways

PathwaySourceExternal ID
Glycerophospholipid metabolismKEGGko00564
Ether lipid metabolismKEGGko00565
Arachidonic acid metabolismKEGGko00590
Linoleic acid metabolismKEGGko00591
alpha-Linolenic acid metabolismKEGGko00592
Glycerophospholipid metabolismKEGGhsa00564
Ether lipid metabolismKEGGhsa00565
Arachidonic acid metabolismKEGGhsa00590
Linoleic acid metabolismKEGGhsa00591
alpha-Linolenic acid metabolismKEGGhsa00592
Metabolic pathwaysKEGGhsa01100
Ras signaling pathwayKEGGhsa04014
Regulation of lipolysis in adipocytesKEGGhsa04923
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Acyl chain remodelling of PEREACTOMER-HSA-1482839
Acyl chain remodelling of PCREACTOMER-HSA-1482788
Acyl chain remodelling of PSREACTOMER-HSA-1482801
Acyl chain remodelling of PIREACTOMER-HSA-1482922

References

Pubmed IDYearTitleCitations
191369642009AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency.94
186145312008Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA).49
280778782017PLA2G16 represents a switch between entry and clearance of Picornaviridae.44
250242032014Pla2g16 phospholipase mediates gain-of-function activities of mutant p53.36
226053812012Structural basis for the acyltransferase activity of lecithin:retinol acyltransferase-like proteins.24
229236162012Structure/function relationships of adipose phospholipase A2 containing a cys-his-his catalytic triad.16
253837592015LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3.14
205016452010Atypical protein kinase C zeta exhibits a proapoptotic function in ovarian cancer.13
170034972006H-REV107-1 stimulates growth in non-small cell lung carcinomas via the activation of mitogenic signaling.12
120547412002Induction of murine H-rev107 gene expression by growth arrest and histone acetylation: involvement of an Sp1/Sp3-binding GC-box.11

Citation

Dessen P

PLAAT3 (phospholipase A and acyltransferase 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40864/plaat3