PLCD1 (phospholipase C, delta 1)

Identity

Other names	-
HGNC	PLCD1
Location	3p22-p21.3
Location_base_pair	Starts at 38023991 and ends at 38046137 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PLCD1   9060
Entrez_Gene	PLCD1  5333  phospholipase C, delta 1
	Cards
GeneCards	PLCD1
Ensembl	ENSG00000187091 [Gene_View]  PLCD1 [Vega]
Genatlas	PLCD1
	Genomic and cartography
GoldenPath	PLCD1  -     chr3:38023991-38046137 -  3p22.2   [Description]    (hg18-March_2006)
Ensembl	PLCD1 - 3p22.2 [CytoView]
NCBI	Mapview
OMIM	602142 Disease map [OMIM]
HomoloGene	PLCD1
	Gene and transcription
Genbank	AB209862 [ ENTREZ ]
Genbank	AK090774 [ ENTREZ ]
Genbank	AK098690 [ ENTREZ ]
Genbank	AK127813 [ ENTREZ ]
Genbank	AK292324 [ ENTREZ ]
RefSeq	NM_006225 [ SRS ]    NM_006225 [ ENTREZ ]
RefSeq	AC_000046 [ SRS ]    AC_000046 [ ENTREZ ]
RefSeq	AC_000135 [ SRS ]    AC_000135 [ ENTREZ ]
RefSeq	NC_000003 [ SRS ]    NC_000003 [ ENTREZ ]
RefSeq	NT_022517 [ SRS ]    NT_022517 [ ENTREZ ]
RefSeq	NW_001838877 [ SRS ]    NW_001838877 [ ENTREZ ]
RefSeq	NW_921651 [ SRS ]    NW_921651 [ ENTREZ ]
CCDS	PLCD1 CCDS - NCBI
AceView	PLCD1 AceView - NCBI
Unigene	Hs.80776 [ SRS ]    Hs.80776 [ NCBI ]
Fast-db	3982 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P51178 [ SRS]    P51178 [ EXPASY ]     P51178 [ INTERPRO ]     P51178 [ UNIPROT ] P51178 [ VarSplice FASTA ]
Prosite	PS50004 C2 [ SRS ]    PS50004 C2 [ Expasy ]
Prosite	PS00018 EF_HAND_1 [ SRS ]    PS00018 EF_HAND_1 [ Expasy ]
Prosite	PS50222 EF_HAND_2 [ SRS ]    PS50222 EF_HAND_2 [ Expasy ]
Prosite	PS50003 PH_DOMAIN [ SRS ]    PS50003 PH_DOMAIN [ Expasy ]
Prosite	PS50007 PIPLC_X_DOMAIN [ SRS ]    PS50007 PIPLC_X_DOMAIN [ Expasy ]
Prosite	PS50008 PIPLC_Y_DOMAIN [ SRS ]    PS50008 PIPLC_Y_DOMAIN [ Expasy ]
Interpro	IPR000008 C2_Ca-dep [ SRS ]    IPR000008 C2_Ca-dep [ EBI ]
Interpro	IPR011992 EF-Hand_type [ SRS ]    IPR011992 EF-Hand_type [ EBI ]
Interpro	IPR002048 EF_hand_Ca_bd [ SRS ]    IPR002048 EF_hand_Ca_bd [ EBI ]
Interpro	IPR001849 PH [ SRS ]    IPR001849 PH [ EBI ]
Interpro	IPR011993 PH_type [ SRS ]    IPR011993 PH_type [ EBI ]
Interpro	IPR015359 Phospholipase_C_EF-hand-like [ SRS ]    IPR015359 Phospholipase_C_EF-hand-like [ EBI ]
Interpro	IPR001192 Phospholipase_C_Pinositol-sp_C [ SRS ]    IPR001192 Phospholipase_C_Pinositol-sp_C [ EBI ]
Interpro	IPR000909 Phospholipase_C_Pinositol-sp_X [ SRS ]    IPR000909 Phospholipase_C_Pinositol-sp_X [ EBI ]
Interpro	IPR001711 Phospholipase_C_Pinositol-sp_Y [ SRS ]    IPR001711 Phospholipase_C_Pinositol-sp_Y [ EBI ]
CluSTr	P51178
Pfam	PF00168 C2 [ SRS ]    PF00168 C2 [ Sanger ]    pfam00168 [ NCBI-CDD ]
Pfam	PF00036 efhand [ SRS ]    PF00036 efhand [ Sanger ]    pfam00036 [ NCBI-CDD ]
Pfam	PF09279 efhand_like [ SRS ]    PF09279 efhand_like [ Sanger ]    pfam09279 [ NCBI-CDD ]
Pfam	PF00169 PH [ SRS ]    PF00169 PH [ Sanger ]    pfam00169 [ NCBI-CDD ]
Pfam	PF00388 PI-PLC-X [ SRS ]    PF00388 PI-PLC-X [ Sanger ]    pfam00388 [ NCBI-CDD ]
Pfam	PF00387 PI-PLC-Y [ SRS ]    PF00387 PI-PLC-Y [ Sanger ]    pfam00387 [ NCBI-CDD ]
Smart	SM00239 C2 [EMBL]
Smart	SM00054 EFh [EMBL]
Smart	SM00233 PH [EMBL]
Smart	SM00148 PLCXc [EMBL]
Smart	SM00149 PLCYc [EMBL]
Prodom	PD001202 PI_PLC_Y[INRA-Toulouse]
Prodom	P51178 PLCD1_HUMAN [ Domain structure ]   P51178 PLCD1_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P51178
HPRD	09073
	Protein Interaction databases
DIP	P51178
IntAct	P51178
	Polymorphism : SNP, mutations, diseases
OMIM	602142    [ map ]
GENETests	602142
SNP	PLCD1 [dbSNP-NCBI]
SNP	NM_006225 [SNP-NCI]
SNP	PLCD1 [GeneSNPs - Utah]  PLCD1] [HGBASE - SRS]
HAPMAP	PLCD1 [HAPMAP]
COSMIC	PLCD1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PLCD1
Genetic Association	PLCD1
CDC HuGE	PLCD1
	General knowledge
Family Browser	PLCD1 [UCSC Family Browser]
SOURCE	NM_006225
SMD	Hs.80776
SAGE	Hs.80776
Enzyme	3.1.4.11 [ Enzyme-Expasy ]   3.1.4.11 [ Enzyme-SRS ]   3.1.4.11 [ IntEnz-EBI ]   3.1.4.11 [ BRENDA ]   3.1.4.11 [ KEGG ]
GO	phosphoinositide phospholipase C activity [Amigo]  phosphoinositide phospholipase C activity
GO	phosphoinositide phospholipase C activity [Amigo]  phosphoinositide phospholipase C activity
GO	signal transducer activity [Amigo]  signal transducer activity
GO	calcium ion binding [Amigo]  calcium ion binding
GO	cytoplasm [Amigo]  cytoplasm
GO	lipid metabolic process [Amigo]  lipid metabolic process
GO	phospholipid metabolic process [Amigo]  phospholipid metabolic process
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	lipid catabolic process [Amigo]  lipid catabolic process
GO	hydrolase activity [Amigo]  hydrolase activity
BIOCARTA	Phospholipase C d1 in phospholipid associated cell signaling    [Genes]
KEGG	Inositol phosphate metabolism
KEGG	Calcium signaling pathway
KEGG	Phosphatidylinositol signaling system
PubGene	PLCD1
TreeFam	PLCD1
CTD	5333 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PLCD1 Related clones (RZPD - Berlin)
	PubMed
PubMed	30 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:04:03 2008