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PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3)

Identity

Alias_namesphosphatidylinositol-specific phospholipase C
Other alias-
HGNC (Hugo) PLCXD3
LocusID (NCBI) 345557
Atlas_Id 47476
Location 5p13.1  [Link to chromosome band 5p13]
Location_base_pair Starts at 41307048 and ends at 41510730 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PRLR (5p13.2) / PLCXD3 (5p13.1)WDR70 (5p13.2) / PLCXD3 (5p13.1)PRLR 5p13.2 / PLCXD3 5p13.1
WDR70 5p13.2 / PLCXD3 5p13.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLCXD3   31822
Cards
Entrez_Gene (NCBI)PLCXD3  345557  phosphatidylinositol specific phospholipase C X domain containing 3
Aliases
GeneCards (Weizmann)PLCXD3
Ensembl hg19 (Hinxton)ENSG00000182836 [Gene_View]  chr5:41307048-41510730 [Contig_View]  PLCXD3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000182836 [Gene_View]  chr5:41307048-41510730 [Contig_View]  PLCXD3 [Vega]
ICGC DataPortalENSG00000182836
TCGA cBioPortalPLCXD3
AceView (NCBI)PLCXD3
Genatlas (Paris)PLCXD3
WikiGenes345557
SOURCE (Princeton)PLCXD3
Genetics Home Reference (NIH)PLCXD3
Genomic and cartography
GoldenPath hg19 (UCSC)PLCXD3  -     chr5:41307048-41510730 -  5p13.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PLCXD3  -     5p13.1   [Description]    (hg38-Dec_2013)
EnsemblPLCXD3 - 5p13.1 [CytoView hg19]  PLCXD3 - 5p13.1 [CytoView hg38]
Mapping of homologs : NCBIPLCXD3 [Mapview hg19]  PLCXD3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK124638 AK127142 BC148398 BC156734 BX501895
RefSeq transcript (Entrez)NM_001005473
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_006576 NW_004929321
Consensus coding sequences : CCDS (NCBI)PLCXD3
Cluster EST : UnigeneHs.145404 [ NCBI ]
CGAP (NCI)Hs.145404
Alternative Splicing GalleryENSG00000182836
Gene ExpressionPLCXD3 [ NCBI-GEO ]   PLCXD3 [ EBI - ARRAY_EXPRESS ]   PLCXD3 [ SEEK ]   PLCXD3 [ MEM ]
Gene Expression Viewer (FireBrowse)PLCXD3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)345557
GTEX Portal (Tissue expression)PLCXD3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ63HM9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ63HM9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ63HM9
Splice isoforms : SwissVarQ63HM9
PhosPhoSitePlusQ63HM9
Domaine pattern : Prosite (Expaxy)PIPLC_X_DOMAIN (PS50007)   
Domains : Interpro (EBI)PLC-like_Pdiesterase_TIM-brl    PLipase_C_PInositol-sp_X_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PLCXD3
DMDM Disease mutations345557
Blocks (Seattle)PLCXD3
SuperfamilyQ63HM9
Human Protein AtlasENSG00000182836
Peptide AtlasQ63HM9
HPRD17860
IPIIPI00470475   
Protein Interaction databases
DIP (DOE-UCLA)Q63HM9
IntAct (EBI)Q63HM9
FunCoupENSG00000182836
BioGRIDPLCXD3
STRING (EMBL)PLCXD3
ZODIACPLCXD3
Ontologies - Pathways
QuickGOQ63HM9
Ontology : AmiGOsignal transducer activity  signal transduction  phosphoric diester hydrolase activity  lipid catabolic process  
Ontology : EGO-EBIsignal transducer activity  signal transduction  phosphoric diester hydrolase activity  lipid catabolic process  
NDEx NetworkPLCXD3
Atlas of Cancer Signalling NetworkPLCXD3
Wikipedia pathwaysPLCXD3
Orthology - Evolution
OrthoDB345557
GeneTree (enSembl)ENSG00000182836
Phylogenetic Trees/Animal Genes : TreeFamPLCXD3
HOVERGENQ63HM9
HOGENOMQ63HM9
Homologs : HomoloGenePLCXD3
Homology/Alignments : Family Browser (UCSC)PLCXD3
Gene fusions - Rearrangements
Fusion : MitelmanPRLR/PLCXD3 [5p13.2/5p13.1]  [t(5;5)(p13;p13)]  
Fusion : MitelmanWDR70/PLCXD3 [5p13.2/5p13.1]  [t(5;5)(p13;p13)]  
Fusion: TCGAPRLR 5p13.2 PLCXD3 5p13.1 BRCA
Fusion: TCGAWDR70 5p13.2 PLCXD3 5p13.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLCXD3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLCXD3
dbVarPLCXD3
ClinVarPLCXD3
1000_GenomesPLCXD3 
Exome Variant ServerPLCXD3
ExAC (Exome Aggregation Consortium)PLCXD3 (select the gene name)
Genetic variants : HAPMAP345557
Genomic Variants (DGV)PLCXD3 [DGVbeta]
DECIPHER (Syndromes)5:41307048-41510730  ENSG00000182836
CONAN: Copy Number AnalysisPLCXD3 
Mutations
ICGC Data PortalPLCXD3 
TCGA Data PortalPLCXD3 
Broad Tumor PortalPLCXD3
OASIS PortalPLCXD3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLCXD3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPLCXD3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PLCXD3
DgiDB (Drug Gene Interaction Database)PLCXD3
DoCM (Curated mutations)PLCXD3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLCXD3 (select a term)
intoGenPLCXD3
Cancer3DPLCXD3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPLCXD3
Genetic Testing Registry PLCXD3
NextProtQ63HM9 [Medical]
TSGene345557
GENETestsPLCXD3
Huge Navigator PLCXD3 [HugePedia]
snp3D : Map Gene to Disease345557
BioCentury BCIQPLCXD3
ClinGenPLCXD3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD345557
Chemical/Pharm GKB GenePA134886053
Clinical trialPLCXD3
Miscellaneous
canSAR (ICR)PLCXD3 (select the gene name)
Probes
Litterature
PubMed1 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLCXD3
EVEXPLCXD3
GoPubMedPLCXD3
iHOPPLCXD3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:21:43 CET 2017

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