PLD2 (phospholipase D2)

Identity

Other names	-
HGNC	PLD2
Location	17p13.3
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PLD2   9068
Entrez_Gene	PLD2  5338  phospholipase D2
	Cards
GeneCards	PLD2
Ensembl	PLD2 [Search_View]   ENSG00000129219 [Gene_View]
Genatlas	PLD2
GeneLynx	PLD2
eGenome	PLD2
euGene	5338
	Genomic and cartography
GoldenPath	PLD2  -  17p13.3   chr17:4657378-4673694 +  17p13.2   [Description]    (hg18-March_2006)
Ensembl	PLD2 - 17p13.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PLD2
	Gene and transcription
Genbank	AB209374 [ ENTREZ ]
Genbank	AF033850 [ ENTREZ ]
Genbank	AF035483 [ ENTREZ ]
Genbank	AF038440 [ ENTREZ ]
Genbank	AF038441 [ ENTREZ ]
RefSeq	NM_002663 [ SRS ]    NM_002663 [ ENTREZ ]
RefSeq	AC_000060 [ SRS ]    AC_000060 [ ENTREZ ]
RefSeq	AC_000149 [ SRS ]    AC_000149 [ ENTREZ ]
RefSeq	NC_000017 [ SRS ]    NC_000017 [ ENTREZ ]
RefSeq	NT_010718 [ SRS ]    NT_010718 [ ENTREZ ]
RefSeq	NW_001838403 [ SRS ]    NW_001838403 [ ENTREZ ]
RefSeq	NW_926584 [ SRS ]    NW_926584 [ ENTREZ ]
AceView	PLD2 AceView - NCBI
Unigene	Hs.104519 [ SRS ]    Hs.104519 [ NCBI ]     HS104519 [ spliceNest ]
Fast-db	1694 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O14939 [ SRS]    O14939 [ EXPASY ]     O14939 [ INTERPRO ]     O14939 [ UNIPROT ]
Prosite	PS50003 PH_DOMAIN [ SRS ]    PS50003 PH_DOMAIN [ Expasy ]
Prosite	PS50035 PLD [ SRS ]    PS50035 PLD [ Expasy ]
Prosite	PS50195 PX [ SRS ]    PS50195 PX [ Expasy ]
Interpro	IPR001849 PH [ SRS ]    IPR001849 PH [ EBI ]
Interpro	IPR015679 Phospholipase_D [ SRS ]    IPR015679 Phospholipase_D [ EBI ]
Interpro	IPR001736 PLD [ SRS ]    IPR001736 PLD [ EBI ]
Interpro	IPR016555 PLipase_D_euk [ SRS ]    IPR016555 PLipase_D_euk [ EBI ]
Interpro	IPR001683 PX [ SRS ]    IPR001683 PX [ EBI ]
CluSTr	O14939
Pfam	PF00169 PH [ SRS ]    PF00169 PH [ Sanger ]    pfam00169 [ NCBI-CDD ]
Pfam	PF00614 PLDc [ SRS ]    PF00614 PLDc [ Sanger ]    pfam00614 [ NCBI-CDD ]
Pfam	PF00787 PX [ SRS ]    PF00787 PX [ Sanger ]    pfam00787 [ NCBI-CDD ]
Smart	SM00233 PH [EMBL]
Smart	SM00155 PLDc [EMBL]
Smart	SM00312 PX [EMBL]
Blocks	O14939
HPRD	03857
	Protein Interaction databases
DIP	O14939
IntAct	O14939
	Polymorphism : SNP, mutations, diseases
OMIM	602384    [ map ]
GENECLINICS	602384
SNP	PLD2 [dbSNP-NCBI]
SNP	NM_002663 [SNP-NCI]
SNP	PLD2 [GeneSNPs - Utah]  PLD2] [HGBASE - SRS]
HAPMAP	PLD2 [HAPMAP]
COSMIC	PLD2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PLD2
	General knowledge
Family Browser	PLD2 [UCSC Family Browser]
SOURCE	NM_002663
SMD	Hs.104519
SAGE	Hs.104519
Enzyme	3.1.4.4 [ Enzyme-Expasy ]   3.1.4.4 [ Enzyme-SRS ]   3.1.4.4 [ IntEnz-EBI ]   3.1.4.4 [ BRENDA ]   3.1.4.4 [ KEGG ]   3.1.4.4 [ WIT ]
GO	G-protein coupled receptor internalization [Amigo]  G-protein coupled receptor internalization
GO	catalytic activity [Amigo]  catalytic activity
GO	phospholipase D activity [Amigo]  phospholipase D activity
GO	protein binding [Amigo]  protein binding
GO	plasma membrane [Amigo]  plasma membrane
GO	receptor-mediated endocytosis [Amigo]  receptor-mediated endocytosis
GO	cytoskeleton organization and biogenesis [Amigo]  cytoskeleton organization and biogenesis
GO	cell communication [Amigo]  cell communication
GO	small GTPase mediated signal transduction [Amigo]  small GTPase mediated signal transduction
GO	metabolic process [Amigo]  metabolic process
GO	lipid catabolic process [Amigo]  lipid catabolic process
GO	hydrolase activity [Amigo]  hydrolase activity
GO	brush border membrane [Amigo]  brush border membrane
GO	phosphoinositide binding [Amigo]  phosphoinositide binding
BIOCARTA	Metabolism of Anandamide, an Endogenous Cannabinoid    [Genes]
KEGG	Glycerophospholipid metabolism
KEGG	GnRH signaling pathway
PubGene	PLD2
TreeFam	PLD2
CTD	5338 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PLD2 Related clones (RZPD - Berlin)
	PubMed
PubMed	67 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:25:17 2008