PLEKHA5 (pleckstrin homology domain containing A5)

2007-04-01  

Identity

HGNC
LOCATION
12p12.3
LOCUSID
ALIAS
PEPP-2,PEPP2
FUSION GENES

Other Information

Locus ID:

NCBI: 54477
MIM: 607770
HGNC: 30036
Ensembl: ENSG00000052126

Variants:

dbSNP: 54477
ClinVar: 54477
TCGA: ENSG00000052126
COSMIC: PLEKHA5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000052126ENST00000299275Q9HAU0
ENSG00000052126ENST00000424268Q9HAU0
ENSG00000052126ENST00000429027Q9HAU0
ENSG00000052126ENST00000536974B4DJX4
ENSG00000052126ENST00000538305F5H1X3
ENSG00000052126ENST00000538677H0YG48
ENSG00000052126ENST00000538714Q9HAU0
ENSG00000052126ENST00000538714A0A024RAY7
ENSG00000052126ENST00000538972H0YGJ6
ENSG00000052126ENST00000539256A0JP02
ENSG00000052126ENST00000540972Q9HAU0

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
PI MetabolismREACTOMER-HSA-1483255
Synthesis of PIPs at the plasma membraneREACTOMER-HSA-1660499

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
253168112015PLEKHA5 as a Biomarker and Potential Mediator of Melanoma Brain Metastasis.24
304548822019High genetic risk scores of SLIT3, PLEKHA5 and PPP2R2C variants increased insulin resistance and interacted with coffee and caffeine consumption in middle-aged adults.3

Citation

Dessen P

PLEKHA5 (pleckstrin homology domain containing A5)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46847/plekha5