Identity
HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
ARHGEF42,CLG,CTB-60E11.4,LDAMD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64857
MIM: 611893
HGNC: 29515
Ensembl: ENSG00000090924
Variants:
dbSNP: 64857
ClinVar: 64857
TCGA: ENSG00000090924
COSMIC: PLEKHG2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 28489964 | 2019 | Specific activation of PLEKHG2-induced serum response element-dependent gene transcription by four-and-a-half LIM domains (FHL) 1, but not FHL2 or FHL3. | 4 |
| 28489964 | 2019 | Specific activation of PLEKHG2-induced serum response element-dependent gene transcription by four-and-a-half LIM domains (FHL) 1, but not FHL2 or FHL3. | 4 |
| 28108261 | 2017 | Heterotrimeric G protein Gαs subunit attenuates PLEKHG2, a Rho family-specific guanine nucleotide exchange factor, by direct interaction. | 2 |
| 28108261 | 2017 | Heterotrimeric G protein Gαs subunit attenuates PLEKHG2, a Rho family-specific guanine nucleotide exchange factor, by direct interaction. | 2 |
| 26573021 | 2016 | Microcephaly-dystonia due to mutated PLEKHG2 with impaired actin polymerization. | 6 |
| 27765816 | 2016 | Four-and-a-half LIM Domains 1 (FHL1) Protein Interacts with the Rho Guanine Nucleotide Exchange Factor PLEKHG2/FLJ00018 and Regulates Cell Morphogenesis. | 5 |
| 26573021 | 2016 | Microcephaly-dystonia due to mutated PLEKHG2 with impaired actin polymerization. | 6 |
| 27765816 | 2016 | Four-and-a-half LIM Domains 1 (FHL1) Protein Interacts with the Rho Guanine Nucleotide Exchange Factor PLEKHG2/FLJ00018 and Regulates Cell Morphogenesis. | 5 |
| 25213431 | 2015 | Autoantibodies binding to ubiquitin-fold modifier-conjugating enzyme 1 (Ufc1) and pleckstrin homology domain containing, family G (with RhoGef domain) member 2 (Plekhg2) are associated with mycobacterial infections. | 0 |
| 25213431 | 2015 | Autoantibodies binding to ubiquitin-fold modifier-conjugating enzyme 1 (Ufc1) and pleckstrin homology domain containing, family G (with RhoGef domain) member 2 (Plekhg2) are associated with mycobacterial infections. | 0 |
| 24378532 | 2014 | PLEKHG2/FLJ00018, a Rho family-specific guanine nucleotide exchange factor, is tyrosine phosphorylated via the EphB2/cSrc signaling pathway. | 5 |
| 24554703 | 2014 | Threonine 680 phosphorylation of FLJ00018/PLEKHG2, a Rho family-specific guanine nucleotide exchange factor, by epidermal growth factor receptor signaling regulates cell morphology of Neuro-2a cells. | 7 |
| 24378532 | 2014 | PLEKHG2/FLJ00018, a Rho family-specific guanine nucleotide exchange factor, is tyrosine phosphorylated via the EphB2/cSrc signaling pathway. | 5 |
| 24554703 | 2014 | Threonine 680 phosphorylation of FLJ00018/PLEKHG2, a Rho family-specific guanine nucleotide exchange factor, by epidermal growth factor receptor signaling regulates cell morphology of Neuro-2a cells. | 7 |
| 23000341 | 2013 | Identification of a Rho family specific guanine nucleotide exchange factor, FLJ00018, as a novel actin-binding protein. | 5 |
Citation
Dessen P
PLEKHG2 (pleckstrin homology and RhoGEF domain containing G2)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/40101/plekhg2
