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PLEKHO2 (pleckstrin homology domain containing O2)

Identity

Alias_namesPLEKHQ1
pleckstrin homology domain containing, family Q member 1
pleckstrin homology domain containing, family O member 2
Alias_symbol (synonym)DKFZp761K2312
PP1628
pp9099
Other alias
HGNC (Hugo) PLEKHO2
LocusID (NCBI) 80301
Atlas_Id 71990
Location 15q22.31  [Link to chromosome band 15q22]
Location_base_pair Starts at 64841883 and ends at 64868002 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PLEKHO2 (15q22.31) / ANKDD1A (15q22.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLEKHO2   30026
Cards
Entrez_Gene (NCBI)PLEKHO2  80301  pleckstrin homology domain containing O2
AliasesPLEKHQ1; PP1628; pp9099
GeneCards (Weizmann)PLEKHO2
Ensembl hg19 (Hinxton)ENSG00000241839 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000241839 [Gene_View]  chr15:64841883-64868002 [Contig_View]  PLEKHO2 [Vega]
ICGC DataPortalENSG00000241839
TCGA cBioPortalPLEKHO2
AceView (NCBI)PLEKHO2
Genatlas (Paris)PLEKHO2
WikiGenes80301
SOURCE (Princeton)PLEKHO2
Genetics Home Reference (NIH)PLEKHO2
Genomic and cartography
GoldenPath hg38 (UCSC)PLEKHO2  -     chr15:64841883-64868002 +  15q22.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLEKHO2  -     15q22.31   [Description]    (hg19-Feb_2009)
EnsemblPLEKHO2 - 15q22.31 [CytoView hg19]  PLEKHO2 - 15q22.31 [CytoView hg38]
Mapping of homologs : NCBIPLEKHO2 [Mapview hg19]  PLEKHO2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF217986 AF318373 AF494534 AK096203 AL157457
RefSeq transcript (Entrez)NM_001195059 NM_025201
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLEKHO2
Cluster EST : UnigeneHs.709337 [ NCBI ]
CGAP (NCI)Hs.709337
Alternative Splicing GalleryENSG00000241839
Gene ExpressionPLEKHO2 [ NCBI-GEO ]   PLEKHO2 [ EBI - ARRAY_EXPRESS ]   PLEKHO2 [ SEEK ]   PLEKHO2 [ MEM ]
Gene Expression Viewer (FireBrowse)PLEKHO2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80301
GTEX Portal (Tissue expression)PLEKHO2
Human Protein AtlasENSG00000241839-PLEKHO2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TD55   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TD55  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TD55
Splice isoforms : SwissVarQ8TD55
PhosPhoSitePlusQ8TD55
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)PH (PF00169)   
Domain families : Pfam (NCBI)pfam00169   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)PLEKHO2
DMDM Disease mutations80301
Blocks (Seattle)PLEKHO2
SuperfamilyQ8TD55
Human Protein Atlas [tissue]ENSG00000241839-PLEKHO2 [tissue]
Peptide AtlasQ8TD55
HPRD15910
IPIIPI00332493   IPI00791133   IPI01015109   IPI00018785   IPI00790205   
Protein Interaction databases
DIP (DOE-UCLA)Q8TD55
IntAct (EBI)Q8TD55
FunCoupENSG00000241839
BioGRIDPLEKHO2
STRING (EMBL)PLEKHO2
ZODIACPLEKHO2
Ontologies - Pathways
QuickGOQ8TD55
Ontology : AmiGOextracellular region  neutrophil degranulation  ficolin-1-rich granule lumen  
Ontology : EGO-EBIextracellular region  neutrophil degranulation  ficolin-1-rich granule lumen  
Pathways : KEGGCytokine-cytokine receptor interaction   
NDEx NetworkPLEKHO2
Atlas of Cancer Signalling NetworkPLEKHO2
Wikipedia pathwaysPLEKHO2
Orthology - Evolution
OrthoDB80301
GeneTree (enSembl)ENSG00000241839
Phylogenetic Trees/Animal Genes : TreeFamPLEKHO2
HOVERGENQ8TD55
HOGENOMQ8TD55
Homologs : HomoloGenePLEKHO2
Homology/Alignments : Family Browser (UCSC)PLEKHO2
Gene fusions - Rearrangements
Tumor Fusion PortalPLEKHO2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLEKHO2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLEKHO2
dbVarPLEKHO2
ClinVarPLEKHO2
1000_GenomesPLEKHO2 
Exome Variant ServerPLEKHO2
ExAC (Exome Aggregation Consortium)ENSG00000241839
GNOMAD BrowserENSG00000241839
Genetic variants : HAPMAP80301
Genomic Variants (DGV)PLEKHO2 [DGVbeta]
DECIPHERPLEKHO2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLEKHO2 
Mutations
ICGC Data PortalPLEKHO2 
TCGA Data PortalPLEKHO2 
Broad Tumor PortalPLEKHO2
OASIS PortalPLEKHO2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLEKHO2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPLEKHO2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PLEKHO2
DgiDB (Drug Gene Interaction Database)PLEKHO2
DoCM (Curated mutations)PLEKHO2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLEKHO2 (select a term)
intoGenPLEKHO2
Cancer3DPLEKHO2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPLEKHO2
MedgenPLEKHO2
Genetic Testing Registry PLEKHO2
NextProtQ8TD55 [Medical]
TSGene80301
GENETestsPLEKHO2
Target ValidationPLEKHO2
Huge Navigator PLEKHO2 [HugePedia]
snp3D : Map Gene to Disease80301
BioCentury BCIQPLEKHO2
ClinGenPLEKHO2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80301
Chemical/Pharm GKB GenePA162399756
Clinical trialPLEKHO2
Miscellaneous
canSAR (ICR)PLEKHO2 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLEKHO2
EVEXPLEKHO2
GoPubMedPLEKHO2
iHOPPLEKHO2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:07:29 CET 2017

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