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PLEKHS1 (pleckstrin homology domain containing S1)

Identity

Alias_namesC10orf81
chromosome 10 open reading frame 81
pleckstrin homology domain containing, family S member 1
Alias_symbol (synonym)FLJ23537
bA211N11.2
Other aliasHEL185
HGNC (Hugo) PLEKHS1
LocusID (NCBI) 79949
Atlas_Id 71991
Location 10q25.3  [Link to chromosome band 10q25]
Location_base_pair Starts at 113751454 and ends at 113782433 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLEKHS1   26285
Cards
Entrez_Gene (NCBI)PLEKHS1  79949  pleckstrin homology domain containing S1
AliasesC10orf81; HEL185; bA211N11.2
GeneCards (Weizmann)PLEKHS1
Ensembl hg19 (Hinxton)ENSG00000148735 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148735 [Gene_View]  chr10:113751454-113782433 [Contig_View]  PLEKHS1 [Vega]
ICGC DataPortalENSG00000148735
TCGA cBioPortalPLEKHS1
AceView (NCBI)PLEKHS1
Genatlas (Paris)PLEKHS1
WikiGenes79949
SOURCE (Princeton)PLEKHS1
Genetics Home Reference (NIH)PLEKHS1
Genomic and cartography
GoldenPath hg38 (UCSC)PLEKHS1  -     chr10:113751454-113782433 +  10q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLEKHS1  -     10q25.3   [Description]    (hg19-Feb_2009)
EnsemblPLEKHS1 - 10q25.3 [CytoView hg19]  PLEKHS1 - 10q25.3 [CytoView hg38]
Mapping of homologs : NCBIPLEKHS1 [Mapview hg19]  PLEKHS1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK027190 AK126354 AK128811 AK292867 AK296132
RefSeq transcript (Entrez)NM_001193434 NM_001193435 NM_024889 NM_182601
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLEKHS1
Cluster EST : UnigeneHs.228320 [ NCBI ]
CGAP (NCI)Hs.228320
Alternative Splicing GalleryENSG00000148735
Gene ExpressionPLEKHS1 [ NCBI-GEO ]   PLEKHS1 [ EBI - ARRAY_EXPRESS ]   PLEKHS1 [ SEEK ]   PLEKHS1 [ MEM ]
Gene Expression Viewer (FireBrowse)PLEKHS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79949
GTEX Portal (Tissue expression)PLEKHS1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5SXH7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5SXH7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5SXH7
Splice isoforms : SwissVarQ5SXH7
PhosPhoSitePlusQ5SXH7
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)PH (PF00169)   
Domain families : Pfam (NCBI)pfam00169   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)PLEKHS1
DMDM Disease mutations79949
Blocks (Seattle)PLEKHS1
SuperfamilyQ5SXH7
Human Protein AtlasENSG00000148735
Peptide AtlasQ5SXH7
HPRD12591
IPIIPI00477120   IPI00885001   IPI00876978   IPI00418714   IPI00743673   IPI00940472   IPI00513938   
Protein Interaction databases
DIP (DOE-UCLA)Q5SXH7
IntAct (EBI)Q5SXH7
FunCoupENSG00000148735
BioGRIDPLEKHS1
STRING (EMBL)PLEKHS1
ZODIACPLEKHS1
Ontologies - Pathways
QuickGOQ5SXH7
Ontology : AmiGOprotein binding  
Ontology : EGO-EBIprotein binding  
NDEx NetworkPLEKHS1
Atlas of Cancer Signalling NetworkPLEKHS1
Wikipedia pathwaysPLEKHS1
Orthology - Evolution
OrthoDB79949
GeneTree (enSembl)ENSG00000148735
Phylogenetic Trees/Animal Genes : TreeFamPLEKHS1
HOVERGENQ5SXH7
HOGENOMQ5SXH7
Homologs : HomoloGenePLEKHS1
Homology/Alignments : Family Browser (UCSC)PLEKHS1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLEKHS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLEKHS1
dbVarPLEKHS1
ClinVarPLEKHS1
1000_GenomesPLEKHS1 
Exome Variant ServerPLEKHS1
ExAC (Exome Aggregation Consortium)PLEKHS1 (select the gene name)
Genetic variants : HAPMAP79949
Genomic Variants (DGV)PLEKHS1 [DGVbeta]
DECIPHERPLEKHS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLEKHS1 
Mutations
ICGC Data PortalPLEKHS1 
TCGA Data PortalPLEKHS1 
Broad Tumor PortalPLEKHS1
OASIS PortalPLEKHS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLEKHS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPLEKHS1
BioMutasearch PLEKHS1
DgiDB (Drug Gene Interaction Database)PLEKHS1
DoCM (Curated mutations)PLEKHS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLEKHS1 (select a term)
intoGenPLEKHS1
Cancer3DPLEKHS1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPLEKHS1
Genetic Testing Registry PLEKHS1
NextProtQ5SXH7 [Medical]
TSGene79949
GENETestsPLEKHS1
Target ValidationPLEKHS1
Huge Navigator PLEKHS1 [HugePedia]
snp3D : Map Gene to Disease79949
BioCentury BCIQPLEKHS1
ClinGenPLEKHS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79949
Chemical/Pharm GKB GenePA134886856
Clinical trialPLEKHS1
Miscellaneous
canSAR (ICR)PLEKHS1 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLEKHS1
EVEXPLEKHS1
GoPubMedPLEKHS1
iHOPPLEKHS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:34:45 CEST 2017

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