Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PLEKHS1 (pleckstrin homology domain containing S1)

Identity

Alias (NCBI)C10orf81
HEL185
HGNC (Hugo) PLEKHS1
HGNC Alias symbFLJ23537
bA211N11.2
HGNC Previous nameC10orf81
HGNC Previous namechromosome 10 open reading frame 81
 pleckstrin homology domain containing, family S member 1
LocusID (NCBI) 79949
Atlas_Id 71991
Location 10q25.3  [Link to chromosome band 10q25]
Location_base_pair Starts at 113764819 and ends at 113777730 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PLEKHS1   26285
Cards
Entrez_Gene (NCBI)PLEKHS1    pleckstrin homology domain containing S1
AliasesC10orf81; HEL185
GeneCards (Weizmann)PLEKHS1
Ensembl hg19 (Hinxton)ENSG00000148735 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148735 [Gene_View]  ENSG00000148735 [Sequence]  chr10:113764819-113777730 [Contig_View]  PLEKHS1 [Vega]
ICGC DataPortalENSG00000148735
TCGA cBioPortalPLEKHS1
AceView (NCBI)PLEKHS1
Genatlas (Paris)PLEKHS1
SOURCE (Princeton)PLEKHS1
Genetics Home Reference (NIH)PLEKHS1
Genomic and cartography
GoldenPath hg38 (UCSC)PLEKHS1  -     chr10:113764819-113777730 +  10q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLEKHS1  -     10q25.3   [Description]    (hg19-Feb_2009)
GoldenPathPLEKHS1 - 10q25.3 [CytoView hg19]  PLEKHS1 - 10q25.3 [CytoView hg38]
ImmunoBaseENSG00000148735
Genome Data Viewer NCBIPLEKHS1 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK027190 AK126354 AK128811 AK292867 AK296132
RefSeq transcript (Entrez)NM_001193434 NM_001193435 NM_024889 NM_182601
Consensus coding sequences : CCDS (NCBI)PLEKHS1
Gene ExpressionPLEKHS1 [ NCBI-GEO ]   PLEKHS1 [ EBI - ARRAY_EXPRESS ]   PLEKHS1 [ SEEK ]   PLEKHS1 [ MEM ]
Gene Expression Viewer (FireBrowse)PLEKHS1 [ Firebrowse - Broad ]
GenevisibleExpression of PLEKHS1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79949
GTEX Portal (Tissue expression)PLEKHS1
Human Protein AtlasENSG00000148735-PLEKHS1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5SXH7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5SXH7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5SXH7
PhosPhoSitePlusQ5SXH7
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)PH-like_dom_sf    PH_domain    PLEKHS1   
Domain families : Pfam (Sanger)PH (PF00169)   
Domain families : Pfam (NCBI)pfam00169   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)PLEKHS1
SuperfamilyQ5SXH7
AlphaFold pdb e-kbQ5SXH7   
Human Protein Atlas [tissue]ENSG00000148735-PLEKHS1 [tissue]
HPRD12591
Protein Interaction databases
DIP (DOE-UCLA)Q5SXH7
IntAct (EBI)Q5SXH7
BioGRIDPLEKHS1
STRING (EMBL)PLEKHS1
ZODIACPLEKHS1
Ontologies - Pathways
QuickGOQ5SXH7
Ontology : AmiGO
Ontology : EGO-EBI
NDEx NetworkPLEKHS1
Atlas of Cancer Signalling NetworkPLEKHS1
Wikipedia pathwaysPLEKHS1
Orthology - Evolution
OrthoDB79949
GeneTree (enSembl)ENSG00000148735
Phylogenetic Trees/Animal Genes : TreeFamPLEKHS1
Homologs : HomoloGenePLEKHS1
Homology/Alignments : Family Browser (UCSC)PLEKHS1
Gene fusions - Rearrangements
Fusion : QuiverPLEKHS1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLEKHS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLEKHS1
dbVarPLEKHS1
ClinVarPLEKHS1
MonarchPLEKHS1
1000_GenomesPLEKHS1 
Exome Variant ServerPLEKHS1
GNOMAD BrowserENSG00000148735
Varsome BrowserPLEKHS1
ACMGPLEKHS1 variants
VarityQ5SXH7
Genomic Variants (DGV)PLEKHS1 [DGVbeta]
DECIPHERPLEKHS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLEKHS1 
Mutations
ICGC Data PortalPLEKHS1 
TCGA Data PortalPLEKHS1 
Broad Tumor PortalPLEKHS1
OASIS PortalPLEKHS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLEKHS1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPLEKHS1
Mutations and Diseases : HGMDPLEKHS1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPLEKHS1
DgiDB (Drug Gene Interaction Database)PLEKHS1
DoCM (Curated mutations)PLEKHS1
CIViC (Clinical Interpretations of Variants in Cancer)PLEKHS1
Cancer3DPLEKHS1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPLEKHS1
MedgenPLEKHS1
Genetic Testing Registry PLEKHS1
NextProtQ5SXH7 [Medical]
GENETestsPLEKHS1
Target ValidationPLEKHS1
Huge Navigator PLEKHS1 [HugePedia]
ClinGenPLEKHS1
Clinical trials, drugs, therapy
MyCancerGenomePLEKHS1
Protein Interactions : CTDPLEKHS1
Pharm GKB GenePA134886856
PharosQ5SXH7
Clinical trialPLEKHS1
Miscellaneous
canSAR (ICR)PLEKHS1
HarmonizomePLEKHS1
DataMed IndexPLEKHS1
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPLEKHS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 16:16:28 CEST 2021

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