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PLK5 (polo like kinase 5)

Identity

Alias_namesPLK5P
polo-like kinase 5 pseudogene
polo-like kinase 5, pseudogene
polo-like kinase 5
Alias_symbol (synonym)SgK384ps
Other aliasPLK-5
HGNC (Hugo) PLK5
LocusID (NCBI) 126520
Atlas_Id 52363
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 1524074 and ends at 1535456 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLK5   27001
Cards
Entrez_Gene (NCBI)PLK5  126520  polo like kinase 5
AliasesPLK-5; PLK5P; SgK384ps
GeneCards (Weizmann)PLK5
Ensembl hg19 (Hinxton)ENSG00000185988 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185988 [Gene_View]  chr19:1524074-1535456 [Contig_View]  PLK5 [Vega]
ICGC DataPortalENSG00000185988
TCGA cBioPortalPLK5
AceView (NCBI)PLK5
Genatlas (Paris)PLK5
WikiGenes126520
SOURCE (Princeton)PLK5
Genetics Home Reference (NIH)PLK5
Genomic and cartography
GoldenPath hg38 (UCSC)PLK5  -     chr19:1524074-1535456 +  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLK5  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblPLK5 - 19p13.3 [CytoView hg19]  PLK5 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIPLK5 [Mapview hg19]  PLK5 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI651075 AK054808 AK122648 BC100791 BC100792
RefSeq transcript (Entrez)NM_001011716 NM_001243079
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLK5
Cluster EST : UnigeneHs.195352 [ NCBI ]
CGAP (NCI)Hs.195352
Alternative Splicing GalleryENSG00000185988
Gene ExpressionPLK5 [ NCBI-GEO ]   PLK5 [ EBI - ARRAY_EXPRESS ]   PLK5 [ SEEK ]   PLK5 [ MEM ]
Gene Expression Viewer (FireBrowse)PLK5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)126520
GTEX Portal (Tissue expression)PLK5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ496M5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ496M5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ496M5
Splice isoforms : SwissVarQ496M5
PhosPhoSitePlusQ496M5
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)Kinase-like_dom    POLO_box_1    POLO_box_dom    Prot_kinase_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PLK5
DMDM Disease mutations126520
Blocks (Seattle)PLK5
SuperfamilyQ496M5
Human Protein AtlasENSG00000185988
Peptide AtlasQ496M5
IPIIPI00783437   IPI00829623   
Protein Interaction databases
DIP (DOE-UCLA)Q496M5
IntAct (EBI)Q496M5
FunCoupENSG00000185988
BioGRIDPLK5
STRING (EMBL)PLK5
ZODIACPLK5
Ontologies - Pathways
QuickGOQ496M5
Ontology : AmiGOdefense response to tumor cell  protein kinase activity  ATP binding  nucleolus  cytoplasm  protein phosphorylation  cell cycle  positive regulation of neuron projection development  G2 DNA damage checkpoint  cell division  cellular response to growth factor stimulus  regulation of G1/S transition of mitotic cell cycle  
Ontology : EGO-EBIdefense response to tumor cell  protein kinase activity  ATP binding  nucleolus  cytoplasm  protein phosphorylation  cell cycle  positive regulation of neuron projection development  G2 DNA damage checkpoint  cell division  cellular response to growth factor stimulus  regulation of G1/S transition of mitotic cell cycle  
NDEx NetworkPLK5
Atlas of Cancer Signalling NetworkPLK5
Wikipedia pathwaysPLK5
Orthology - Evolution
OrthoDB126520
GeneTree (enSembl)ENSG00000185988
Phylogenetic Trees/Animal Genes : TreeFamPLK5
HOVERGENQ496M5
HOGENOMQ496M5
Homologs : HomoloGenePLK5
Homology/Alignments : Family Browser (UCSC)PLK5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLK5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLK5
dbVarPLK5
ClinVarPLK5
1000_GenomesPLK5 
Exome Variant ServerPLK5
ExAC (Exome Aggregation Consortium)PLK5 (select the gene name)
Genetic variants : HAPMAP126520
Genomic Variants (DGV)PLK5 [DGVbeta]
DECIPHERPLK5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLK5 
Mutations
ICGC Data PortalPLK5 
TCGA Data PortalPLK5 
Broad Tumor PortalPLK5
OASIS PortalPLK5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLK5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPLK5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PLK5
DgiDB (Drug Gene Interaction Database)PLK5
DoCM (Curated mutations)PLK5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLK5 (select a term)
intoGenPLK5
Cancer3DPLK5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPLK5
Genetic Testing Registry PLK5
NextProtQ496M5 [Medical]
TSGene126520
GENETestsPLK5
Target ValidationPLK5
Huge Navigator PLK5 [HugePedia]
snp3D : Map Gene to Disease126520
BioCentury BCIQPLK5
ClinGenPLK5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD126520
Chemical/Pharm GKB GenePA166048975
Clinical trialPLK5
Miscellaneous
canSAR (ICR)PLK5 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLK5
EVEXPLK5
GoPubMedPLK5
iHOPPLK5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:10:56 CEST 2017

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