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PLOD1 (procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1)

Identity

Other namesEDS6
LH
LH1
LLH
PLOD
HGNC (Hugo) PLOD1
LocusID (NCBI) 5351
Location 1p36.22
Location_base_pair Starts at 11994724 and ends at 12035599 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PLOD1   9081
Entrez_Gene (NCBI)PLOD1  5351  procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
Cards
GeneCards (Weizmann)PLOD1
Ensembl (Hinxton)ENSG00000083444 [Gene_View]  chr1:11994724-12035599 [Contig_View]  PLOD1 [Vega]
AceView (NCBI)PLOD1
Genatlas (Paris)PLOD1
SOURCE (Stanford)NM_000302
Genomic and cartography
GoldenPath (UCSC)PLOD1  -  1p36.22   chr1:11994724-12035599 +  1p36.22   [Description]    (hg19-Feb_2009)
EnsemblPLOD1 - 1p36.22 [CytoView]
Mapping of homologs : NCBIPLOD1 [Mapview]
OMIM153454   225400   601451   
Gene and transcription
Genbank (Entrez)AK124035 AK294688 AK295254 AK299150 AK312243
RefSeq transcript (SRS)NM_000302
RefSeq transcript (Entrez)NM_000302
RefSeq genomic (SRS)AC_000133 NC_000001 NC_018912 NG_008159 NT_021937 NW_001838534 NW_004077989
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_008159 NT_021937 NW_001838534 NW_004077989
Consensus coding sequences : CCDS (NCBI)PLOD1
Cluster EST : UnigeneHs.75093 [ SRS ] Hs.75093 [ NCBI ]
CGAP (NCI)Hs.75093
Alternative Splicing : Fast-db (Paris)GSHG0000129
Alternative Splicing GalleryENSG00000083444
Gene ExpressionPLOD1 [ NCBI-GEO ]   PLOD1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ02809 (SRS) Q02809 (Uniprot)
NextProtQ02809
With graphics : InterProQ02809
Splice isoforms : SwissVarQ02809(Swissvar)
Domaine pattern : Prosite (SRS)FE2OG_OXY (PS51471)    LYS_HYDROXYLASE (PS01325)   
Domaine pattern : Prosite (Expaxy)FE2OG_OXY (PS51471)    LYS_HYDROXYLASE (PS01325)   
Domains : Interpro (SRS)Oxoglu/Fe-dep_dioxygenase    Pro_4_hyd_alph    Procol_lys_dOase   
Domains : Interpro (EBI)Oxoglu/Fe-dep_dioxygenase    Pro_4_hyd_alph    Procol_lys_dOase   
Related proteins : CluSTrQ02809
Domain families : Pfam (SRS)2OG-FeII_Oxy (PF03171)   
Domain families : Pfam (Sanger)2OG-FeII_Oxy (PF03171)   
Domain families : Pfam (NCBI)pfam03171   
Domain families : Smart (EMBL)P4Hc (SM00702)  
DMDM5351
Blocks (Seattle)Q02809
Human Protein AtlasENSG00000083444
HPRD01086
IPIIPI00943008   IPI01012138   IPI00027192   IPI00641236   IPI00643385   
Protein Interaction databases
DIP (DOE-UCLA)Q02809
IntAct (EBI)Q02809
FunCoupENSG00000083444
REACTOMEPLOD1
Protein Interaction Database5351
BioGRIDPLOD1
InParanoidQ02809
Interologous Interaction database Q02809
IntegromeDBPLOD1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PLOD1
SNP (GeneSNP Utah)PLOD1
SNP : HGBasePLOD1
Genetic variants : HAPMAPPLOD1
Somatic Mutations in Cancer : COSMICPLOD1 
CONAN: Copy Number AnalysisPLOD1 
Mutations and Diseases : HGMDPLOD1
OMIM153454    225400    601451   
GENETests153454    225400    601451   
Disease Genetic AssociationPLOD1
Huge Navigator PLOD1 [HugePedia]  PLOD1 [HugeCancerGEM]
Genomic VariantsPLOD1  PLOD1 [DGVbeta]
snp3D : Map Gene to Disease5351
General knowledge
Homologs : HomoloGenePLOD1
Homology/Alignments : Family Browser (UCSC)PLOD1
Phylogenetic Trees/Animal Genes : TreeFamPLOD1
Catalytic activity : Enzyme1.14.11.4 [ Enzyme-Expasy ]   1.14.11.4 [ Enzyme-SRS ]   1.14.11.4 [ IntEnz-EBI ]   1.14.11.4 [ BRENDA ]   1.14.11.4 [ KEGG ]   
Chemical/Protein Interactions : CTD5351
Chemical/Pharm GKB GenePA33411
Clinical trialPLOD1
Cancer Resource (Charite)ENSG00000083444
Ontology : AmiGOresponse to hypoxia  iron ion binding  endoplasmic reticulum membrane  cellular protein modification process  procollagen-lysine 5-dioxygenase activity  epidermis development  epidermis development  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen  extracellular matrix organization  rough endoplasmic reticulum membrane  L-ascorbic acid binding  protein homodimerization activity  hydroxylysine biosynthetic process  oxidation-reduction process  
Ontology : EGO-EBIresponse to hypoxia  iron ion binding  endoplasmic reticulum membrane  cellular protein modification process  procollagen-lysine 5-dioxygenase activity  epidermis development  epidermis development  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen  extracellular matrix organization  rough endoplasmic reticulum membrane  L-ascorbic acid binding  protein homodimerization activity  hydroxylysine biosynthetic process  oxidation-reduction process  
Pathways : KEGGLysine degradation
Other databases
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
PubGenePLOD1
iHOPPLOD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:48:30 CEST 2013
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