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PLP2 (proteolipid protein 2 (colonic epithelium-enriched))

Identity

Alias_namesproteolipid protein 2 (colonic epithelium-enriched)
Alias_symbol (synonym)A4
A4-LSB
MGC126187
Other aliasA4LSB
HGNC (Hugo) PLP2
LocusID (NCBI) 5355
Atlas_Id 55524
Location Xp11.23  [Link to chromosome band Xp11]
Location_base_pair Starts at 49028184 and ends at 49031468 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MAGIX (Xp11.23) / PLP2 (Xp11.23)PEX5 (12p13.31) / PLP2 (Xp11.23)PLP2 (Xp11.23) / PLP2 (Xp11.23)
PLP2 (Xp11.23) / STC2 (5q35.1)PLP2 (Xp11.23) / TIMM17B (Xp11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLP2   9087
Cards
Entrez_Gene (NCBI)PLP2  5355  proteolipid protein 2 (colonic epithelium-enriched)
AliasesA4; A4LSB
GeneCards (Weizmann)PLP2
Ensembl hg19 (Hinxton)ENSG00000102007 [Gene_View]  chrX:49028184-49031468 [Contig_View]  PLP2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000102007 [Gene_View]  chrX:49028184-49031468 [Contig_View]  PLP2 [Vega]
ICGC DataPortalENSG00000102007
TCGA cBioPortalPLP2
AceView (NCBI)PLP2
Genatlas (Paris)PLP2
WikiGenes5355
SOURCE (Princeton)PLP2
Genetics Home Reference (NIH)PLP2
Genomic and cartography
GoldenPath hg19 (UCSC)PLP2  -     chrX:49028184-49031468 +  Xp11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PLP2  -     Xp11.23   [Description]    (hg38-Dec_2013)
EnsemblPLP2 - Xp11.23 [CytoView hg19]  PLP2 - Xp11.23 [CytoView hg38]
Mapping of homologs : NCBIPLP2 [Mapview hg19]  PLP2 [Mapview hg38]
OMIM300112   
Gene and transcription
Genbank (Entrez)BC109066 DB220888 L09604
RefSeq transcript (Entrez)NM_002668
RefSeq genomic (Entrez)NC_000023 NC_018934 NG_016420 NT_079573 NW_004929439
Consensus coding sequences : CCDS (NCBI)PLP2
Cluster EST : UnigeneHs.77422 [ NCBI ]
CGAP (NCI)Hs.77422
Alternative Splicing GalleryENSG00000102007
Gene ExpressionPLP2 [ NCBI-GEO ]   PLP2 [ EBI - ARRAY_EXPRESS ]   PLP2 [ SEEK ]   PLP2 [ MEM ]
Gene Expression Viewer (FireBrowse)PLP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5355
GTEX Portal (Tissue expression)PLP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ04941   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ04941  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ04941
Splice isoforms : SwissVarQ04941
PhosPhoSitePlusQ04941
Domaine pattern : Prosite (Expaxy)MARVEL (PS51225)   
Domains : Interpro (EBI)Marvel   
Domain families : Pfam (Sanger)MARVEL (PF01284)   
Domain families : Pfam (NCBI)pfam01284   
Conserved Domain (NCBI)PLP2
DMDM Disease mutations5355
Blocks (Seattle)PLP2
SuperfamilyQ04941
Human Protein AtlasENSG00000102007
Peptide AtlasQ04941
HPRD02121
IPIIPI00030362   IPI00645979   
Protein Interaction databases
DIP (DOE-UCLA)Q04941
IntAct (EBI)Q04941
FunCoupENSG00000102007
BioGRIDPLP2
STRING (EMBL)PLP2
ZODIACPLP2
Ontologies - Pathways
QuickGOQ04941
Ontology : AmiGOprotein binding  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  ion transport  chemotaxis  ion transmembrane transporter activity  membrane  integral component of membrane  cytokine-mediated signaling pathway  chemokine binding  ion transmembrane transport  extracellular exosome  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  ion transport  chemotaxis  ion transmembrane transporter activity  membrane  integral component of membrane  cytokine-mediated signaling pathway  chemokine binding  ion transmembrane transport  extracellular exosome  
NDEx NetworkPLP2
Atlas of Cancer Signalling NetworkPLP2
Wikipedia pathwaysPLP2
Orthology - Evolution
OrthoDB5355
GeneTree (enSembl)ENSG00000102007
Phylogenetic Trees/Animal Genes : TreeFamPLP2
HOVERGENQ04941
HOGENOMQ04941
Homologs : HomoloGenePLP2
Homology/Alignments : Family Browser (UCSC)PLP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLP2
dbVarPLP2
ClinVarPLP2
1000_GenomesPLP2 
Exome Variant ServerPLP2
ExAC (Exome Aggregation Consortium)PLP2 (select the gene name)
Genetic variants : HAPMAP5355
Genomic Variants (DGV)PLP2 [DGVbeta]
DECIPHER (Syndromes)X:49028184-49031468  ENSG00000102007
CONAN: Copy Number AnalysisPLP2 
Mutations
ICGC Data PortalPLP2 
TCGA Data PortalPLP2 
Broad Tumor PortalPLP2
OASIS PortalPLP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPLP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPLP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch PLP2
DgiDB (Drug Gene Interaction Database)PLP2
DoCM (Curated mutations)PLP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLP2 (select a term)
intoGenPLP2
Cancer3DPLP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300112   
Orphanet
MedgenPLP2
Genetic Testing Registry PLP2
NextProtQ04941 [Medical]
TSGene5355
GENETestsPLP2
Huge Navigator PLP2 [HugePedia]
snp3D : Map Gene to Disease5355
BioCentury BCIQPLP2
ClinGenPLP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5355
Chemical/Pharm GKB GenePA33415
Clinical trialPLP2
Miscellaneous
canSAR (ICR)PLP2 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLP2
EVEXPLP2
GoPubMedPLP2
iHOPPLP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:21:51 CET 2017

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