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PLPBP (pyridoxal phosphate binding protein)

Identity

Alias_namesPROSC
proline synthetase co-transcribed (bacterial homolog)
proline synthetase cotranscribed homolog (bacterial)
Other aliasEPVB6D
HGNC (Hugo) PLPBP
LocusID (NCBI) 11212
Atlas_Id 79174
Location 8p11.23  [Link to chromosome band 8p11]
Location_base_pair Starts at 37762583 and ends at 37779768 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PLPBP   9457
Cards
Entrez_Gene (NCBI)PLPBP  11212  pyridoxal phosphate binding protein
AliasesEPVB6D; PROSC
GeneCards (Weizmann)PLPBP
Ensembl hg19 (Hinxton)ENSG00000147471 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147471 [Gene_View]  chr8:37762583-37779768 [Contig_View]  PLPBP [Vega]
ICGC DataPortalENSG00000147471
TCGA cBioPortalPLPBP
AceView (NCBI)PLPBP
Genatlas (Paris)PLPBP
WikiGenes11212
SOURCE (Princeton)PLPBP
Genetics Home Reference (NIH)PLPBP
Genomic and cartography
GoldenPath hg38 (UCSC)PLPBP  -     chr8:37762583-37779768 +  8p11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PLPBP  -     8p11.23   [Description]    (hg19-Feb_2009)
EnsemblPLPBP - 8p11.23 [CytoView hg19]  PLPBP - 8p11.23 [CytoView hg38]
Mapping of homologs : NCBIPLPBP [Mapview hg19]  PLPBP [Mapview hg38]
OMIM604436   617290   
Gene and transcription
Genbank (Entrez)AA463397 AI355650 AK021923 AK291135 AL136616
RefSeq transcript (Entrez)NM_001349346 NM_001349347 NM_001349348 NM_001349349 NM_007198
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PLPBP
Cluster EST : UnigeneHs.608177 [ NCBI ]
CGAP (NCI)Hs.608177
Alternative Splicing GalleryENSG00000147471
Gene ExpressionPLPBP [ NCBI-GEO ]   PLPBP [ EBI - ARRAY_EXPRESS ]   PLPBP [ SEEK ]   PLPBP [ MEM ]
Gene Expression Viewer (FireBrowse)PLPBP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11212
GTEX Portal (Tissue expression)PLPBP
Human Protein AtlasENSG00000147471-PLPBP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94903   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94903  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94903
Splice isoforms : SwissVarO94903
PhosPhoSitePlusO94903
Domaine pattern : Prosite (Expaxy)UPF0001 (PS01211)   
Domains : Interpro (EBI)Ala_racemase_N    COG0325_fam    PLP-binding_barrel   
Domain families : Pfam (Sanger)Ala_racemase_N (PF01168)   
Domain families : Pfam (NCBI)pfam01168   
Conserved Domain (NCBI)PLPBP
DMDM Disease mutations11212
Blocks (Seattle)PLPBP
SuperfamilyO94903
Human Protein Atlas [tissue]ENSG00000147471-PLPBP [tissue]
Peptide AtlasO94903
IPIIPI00902466   IPI00016346   IPI00983735   IPI00983028   IPI00985466   IPI00984829   IPI00981682   
Protein Interaction databases
DIP (DOE-UCLA)O94903
IntAct (EBI)O94903
FunCoupENSG00000147471
BioGRIDPLPBP
STRING (EMBL)PLPBP
ZODIACPLPBP
Ontologies - Pathways
QuickGOO94903
Ontology : AmiGOintracellular  intracellular  cytoplasm  mitochondrion  biological_process  pyridoxal phosphate binding  extracellular exosome  
Ontology : EGO-EBIintracellular  intracellular  cytoplasm  mitochondrion  biological_process  pyridoxal phosphate binding  extracellular exosome  
NDEx NetworkPLPBP
Atlas of Cancer Signalling NetworkPLPBP
Wikipedia pathwaysPLPBP
Orthology - Evolution
OrthoDB11212
GeneTree (enSembl)ENSG00000147471
Phylogenetic Trees/Animal Genes : TreeFamPLPBP
HOVERGENO94903
HOGENOMO94903
Homologs : HomoloGenePLPBP
Homology/Alignments : Family Browser (UCSC)PLPBP
Gene fusions - Rearrangements
Tumor Fusion PortalPLPBP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPLPBP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PLPBP
dbVarPLPBP
ClinVarPLPBP
1000_GenomesPLPBP 
Exome Variant ServerPLPBP
ExAC (Exome Aggregation Consortium)ENSG00000147471
GNOMAD BrowserENSG00000147471
Genetic variants : HAPMAP11212
Genomic Variants (DGV)PLPBP [DGVbeta]
DECIPHERPLPBP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPLPBP 
Mutations
ICGC Data PortalPLPBP 
TCGA Data PortalPLPBP 
Broad Tumor PortalPLPBP
OASIS PortalPLPBP [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPLPBP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PLPBP
DgiDB (Drug Gene Interaction Database)PLPBP
DoCM (Curated mutations)PLPBP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PLPBP (select a term)
intoGenPLPBP
Cancer3DPLPBP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604436    617290   
Orphanet
DisGeNETPLPBP
MedgenPLPBP
Genetic Testing Registry PLPBP
NextProtO94903 [Medical]
TSGene11212
GENETestsPLPBP
Target ValidationPLPBP
Huge Navigator PLPBP [HugePedia]
snp3D : Map Gene to Disease11212
BioCentury BCIQPLPBP
ClinGenPLPBP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11212
Chemical/Pharm GKB GenePA33810
Clinical trialPLPBP
Miscellaneous
canSAR (ICR)PLPBP (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePLPBP
EVEXPLPBP
GoPubMedPLPBP
iHOPPLPBP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:18:50 CET 2017

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